Alzheimer's Disease Genetics Consortium (ADGC) Collection

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The Alzheimer's Disease Genetics Consortium is funded by a grant from the National Institute on Aging (PI, Gerard D. Schellenberg; UO1AG032984), an $18.3 million five-year research grant to conduct genome-wide association studies (GWAS) to identify genes associated with an increased risk of developing late-onset Alzheimer’s disease (LOAD).

More information about ADGC can be found at ADGenetics.org.

ADGC GWAS Datasets From Naj et al. (2011)

Cohort Platform 1000Genomes
(Mar 2012)
Cases / Controls Total Link
Discovery (Stage 1)
ACT Illumina
Human660
Y 365 / 94 2171 NG00034
ADC1 Illumina
Human660
Y 1985 / 523 2731 NG00022
ADC2 Illumina
Human660
Y 688 / 116 926 NG00023
ADNI Illumina
Human660
NA 268 / 173 441 Access Data
GenADA Affymetrix 500 NA 669 / 713 1382 Contact PI
Genetic Differences Illumina
Human660
Y 213 / 0 213 NG00034
UMVUMSSM Illumina
Human660/
1M Duo/
Affymetrix 6.0
Y 1177 / 1123 2462 NG00042
MIRAGE Illumina
Human610/330
Y 491 / 738 1502 NG00031
NIA-LOAD Illumina 610 Y 1798 / 1568 4410 NG00032
OSHU Illumina
Human
CNV370v1_C
NA 647 647 NG00017
TGEN2 Affymetrix 6.0 Y 668 / 365 1511 NG00028
Replication (Stage 2)
ADC3 Illumina
OmniExpress
Y 843 / 430 1526 NG00024
MAYO Illumina
HumanHap300
NA 728 / 1173 2099 NG00043
ROSMAP Affymetrix 6.0 Y 294 / 763 1668 NG00029
UPitt Illumina
Human
Omni1-Quad
Y 1255 / 829 2219 NG00026
WashU Illumina
Human610
Y 259 / 186 576 NG00030

ADGC GWAS Summary Statistics:

Dataset Link
ADGC Summary Statistics- Naj et al. (2011) NG00027
ADGC African American Summary Statistics- Reitz et al. (2013) NG00039
ADGC Neuropath Summary Stats and Phenotypes- Beecham et al. (2014) NG00041
ADGC Age at Onset Summary Statistics- Naj et al. (2014) NG00048
IGAP Summary Statistics ADGC Subset- Lambert et al. (2013) NG00053