Alzheimer's Disease Genetics Consortium (ADGC) Collection

The Alzheimer's Disease Genetics Consortium is funded by a grant from the National Institute on Aging (PI, Gerard D. Schellenberg; UO1AG032984), an $18.3 million five-year research grant to conduct genome-wide association studies (GWAS) to identify genes associated with an increased risk of developing late-onset Alzheimer’s disease (LOAD).

More information about ADGC can be found at ADGenetics.org.

ADGC GWAS Datasets From Naj et al. (2011)

CohortPlatformHapMap21000Genomes (Dec 2010)Cases / ControlsLink
Discovery (Stage 1)
ACTIllumina
Human660
YY354 / 1981NG00034
ADC1Illumina
Human660
YY1566 / 515NG00022
ADC2Illumina
Human660
YY738 / 160NG00023
ADNIIllumina
Human660
NANA268 / 173Access Data
GenADAAffymetrix 500NANA669 / 713Contact PI
Genetic DifferencesIllumina
Human660
YY213 / 0NG00034
UMVUMSSMIllumina
Human660/
1M Duo/
Affymetrix 6.0
YY1177 / 1126NG00042
MIRAGEIllumina
Human610/330
NAY509 / 753NG00031
NIA-LOADIllumina 610YY1852 / 1991NG00032
OSHUIllumina
Human
CNV370v1_C
YY647NG00017
TGEN2Affymetrix 6.0YY864 / 493NG00028
Replication (Stage 2)
ADC3Illumina
OmniExpress
YY897 / 588NG00024
MAYOIllumina
HumanHap300
YY728 / 1173NG00043
ROSMAPAffymetrix 6.0YY296 / 776NG00029
UPittIllumina
Human
Omni1-Quad
YY1440 / 1000NG00026
WashUIllumina
Human610
YY403 / 225NG00030

ADGC GWAS Summary Statistics:

DatasetLink
ADGC Summary Statistics- Naj et al. (2011)NG00027
ADGC African American Summary Statistics- Reitz et al. (2013)NG00039
ADGC Neuropath Summary Stats and Phenotypes- Beecham et al. (2014)NG00041
ADGC Age at Onset Summary Statistics- Naj et al. (2014)NG00048
IGAP Summary Statistics ADGC Subset- Lambert et al. (2013)NG00053