Explore Alzheimer's Disease genetics and genomic annotations using the NIAGADS Genomics Database.
Coming soon: GenomicsDB v.40
includes: linkage disequilibrium and interactive LocusZoom plots; INFERNO reports of GWAS summary statistics datasets, and more...
Check it out (Beta)Dataset Highlights
IGAP
NG00036: Summary statistics from the International Genomics of Alzheimer's Project (IGAP) 2013 meta-analysis of genome-wide association (GWAS) data in Alzheimer's disease
Explore this datasetADSP
NG00061: Variants and annotations from the Discovery Phase of the Alzheimer's Disease Sequencing Project (ADSP)
NG00065: Gene-level genetic evidence for AD based on analysis of exonic ADSP variants *CADD-filtered ADSP Case/Control gene-risk data are currently unavailable while an update to these data is being made.*
Explore these datasets
Explore
The GenomicsDB provides a genome browser that allows comparison of AD GWAS summary statistics tracks to sequence variation and transcriptional regulation.
Not sure where to start? Search for your favorite gene or variant to explore its genomic context and then switch to a full browser view to add additional tracks.

Analyze
Search strategies make it easy to ask sophisticated questions about your data. Find variants associated with AD in NIAGADS GWAS datasets or explore all available searches.
Upload a gene list and take advantage of our functional and pathway enrichment tool to gain new insight into an existing dataset.
Browse our example search strategies for some ideas.

Share
Found something interesting? Download your result for further analysis.
Registered users can share strategy and analysis results with the community or generate a static link for a publication.
Bookmark your favorite genes and variants and save and annotate strategies to create a personalized workspace.
Dataset Highlights
NG00036: IGAP 2013

Dataset Highlights
NG00061: ADSP Variant Annotation

Dataset Highlights
NG00065: ADSP Discovery Phase Case/Control Whole-Exome Sequencing

- Search gene results
*CADD-filtered ADSP Case/Control gene-risk data are currently unavailable while an update to these data is being made.*
- View detailed gene-level results (e.g., TREM2)
- Request access to the full dataset