News

The Alzheimer's Disease Genetics Consortium (ADGC) and the International Genomics of Alzheimer’s Project (IGAP) performed the largest genetic wide association study (GWAS) to date to discover risk loci for LOAD. Their meta-analysis implicates Abeta, Tau, immunity and lipid processing. The paper on Alzheimer's disease genetic association has been published on bioRxiv and can be found here . Meta-analysis of genetic association with diagnosed Alzheimer's disease identifies novel risk loci and implicates Abeta, Tau, immunity and lipid processing Brian W. Kunkle, Benjamin Grenier-Boley, Rebecca...
NIAGADS is pleased to announce the release of the Genomics Database v. 3.1, which features a major face lift intended to improve user experience. NIAGADS GenomicsDB is a public resource that researchers can access without having to formally request data. This release greatly improves the visualization of summary statistics on the genome browser section of the site and adopts positional variant identifiers to allow more precise linkage of annotations to variants. It also introduces new variant annotations such as 1000 Genomes population frequencies, a shift from NCBI to Ensembl for the gene...
ISTAART, the Alzheimer’s Association’s society for physicians and scientists interested in ADRD research, featured members Li-San Wang and Andrew Saykin recently in their e-newsletter. The feature highlighted a CBS article that both Wang and Saykin were quoted in in October about advances in machine learning and artificial intelligence. The full CBS article can be found here .
“Can the machine invasion help save your brain?” CBS explores this question in an October 27 article about the development of technology as it relates to advances in Alzheimer’s disease. While the amount of genetic data available has increased in recent years, the speed at which it gets sifted through also needs to increase in order to effectively pinpoint detection and risk factors for the disease. Cloud storage systems have been particularly helpful in this regard, the article notes. Li-San Wang, Principal Investigator for NIAGADS at UPenn, says, "We're talking about moving hundreds of...
Effective May 1, 2017, NIH will begin permitting access to data with an “Alzheimer’s disease only” data use limitation if the data access request includes research on Alzheimer’s disease or the ADRDs delineated above. Updating the definition of Alzheimer's disease used to establish data-sharing criteria will allow advancement of research on dementia-causing disease processes that are commonly embedded in and/or are difficult to distinguish from AD during life. This clarification will allow approved users of Alzheimer's disease genomic data to pursue research that is fully congruent with the...
ADRD / NIA
The National Institute on Aging is requesting comments and suggestions from the public regarding the proposed FY2019 Bypass Budget for Alzheimer's Disease and Related Dementias. Comments are limited to 300 words or less, and are due by March 27, 2017. Read more at Inside NIA .
NIA / ADRD