Dataset

NG00050 - GWAS of CLU, A potential endophenotype for Alzheimer's disease

Overview

Genome wide association study to understand the role of Clusterin (CLU - Endophenotype for AD) in Alzheimer's Disease. Imputed data consists of 6,015,512 SNPS using 1000 Genomes data (June 2011 release) CEU (build 37) as a reference. This study involves 673 individuals (400 ADRC, 273 ADNI). We provide access to 400 ADRC subjects, remaining data for 273 ADNI subjects can be obtained at adni.loni.usc.edu.
The data provided in this dataset has genotype information for 50 individuals, data for the remaining 350 subjects are available through NIAGADS dataset NG00035.

NIAGADS staff is collecting Genomic Data Sharing (GDS) documentation for this dataset. Until we know how the study's cohort's Institutional Review Board wants the data to be shared, the data cannot be distributed. Information about GDS is available at https://osp.od.nih.gov/scientific-sharing/genomic-data-sharing/. If you have questions about GDS, you may contact Dr. Marilyn Miller, millerm@nia.nih.gov. In the meantime, you may still submit a request for this dataset, but it will not be distributed until GDS documentation is complete.

Molecular Data Type

Type

Disease

AD
Samples

Total subjects- 673
Knight ADRC- 400
ADNI- 273 (apply for access through ADNI)

Phenotypes
Markers

6015512

Platform