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Dataset

NG00035 - GWAS of CSF tau levels identifies risk variants for AD

Overview

Cerebrospinal fluid (CSF) tau, tau phosphorylated at threonine 181 (ptau), and Aβ₄₂ are established biomarkers for Alzheimer's disease (AD) and have been used as quantitative traits for genetic analyses.  This is the largest genome-wide association study for cerebrospinal fluid (CSF) tau/ptau levels published to date (n = 1,269).  Imputed data consists of 5,815,690 SNPS using HapMap release 22 CEU (build 36) as a reference panel.

Contact ADNI to apply for access to their GWAS data at adni.loni.usc.edu.

This dataset is part of the Knight ADRC Collection. Other datasets in this collection can be found at: https://www.niagads.org/knight-adrc-collection

Molecular Data Type

Disease

AD
Submission date: 
3/17/2014
Samples

Total Samples- 1164
WU- 507
UW- 208
UPenn- 55
ADNI- 395- apply for access through ADNI

Phenotypes
Markers

5815690

Platform
PI Information