This work was supported by grants from the NIH [R01AG044546 (to C.C.), P01AG003991 (to C. Cruchaga), RF1AG053303 (to C. Cruchaga), RF1AG058501 (to C. Cruchaga), U01AG058922 (to C. Cruchaga), K01AG046374 (to C.M.K.), and R01HL119813 (to T.J.B.)]. C. Cruchaga was also supported by the Alzheimer’s Association (NIRG-11-200110, BAND-14-338165, AARG-16-441560, and BFG-15-362540). Y.D. was supported by an NIMH institutional training grant (T32MH014877). L.P. was supported by a grant from the Fondazione Italiana Sclerosi Multipla (FISM 2017/R/20). F.F. was supported by a Fondazione Veronesi fellowship. C. Cantoni was supported during the course of this study by a fellowship from the National Multiple Sclerosis Society (FG 2010-A1/2). B.A.B. is supported by 2018 pilot funding from the Hope Center for Neurological Disorders and the Danforth Foundation Challenge at Washington University. The recruitment and clinical characterization of research participants at Washington University was supported by NIH P50 AG05681, P01 AG03991, and P01 AG026276
