Alzheimer Disease
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“Elevated amyloid beta protein (Abeta42) and late onset Alzheimer's disease are associated with single nucleotide polymorphisms in the urokinase-type plasminogen activator gene.”,
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“Variation in the urokinase-plasminogen activator gene does not explain the chromosome 10 linkage signal for late onset AD.”,
Am J Med Genet B Neuropsychiatr Genet, vol. 124B, no. 1, pp. 29-37, 2004.
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“Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score.”,
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“Association studies between risk for late-onset Alzheimer's disease and variants in insulin degrading enzyme.”,
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M. I. Kamboh, Barmada, M. M., Demirci, F. Y., Minster, R. L., Carrasquillo, M. M., Pankratz, V. S., Younkin, S. G., Saykin, A. J., Sweet, R. A., Feingold, E., DeKosky, S. T., and Lopez, O. L.,
“Genome-wide association analysis of age-at-onset in Alzheimer's disease.”,
Mol Psychiatry, vol. 17, no. 12, pp. 1340-6, 2012.
M. Malik, Chiles, J., Xi, H. S., Medway, C., Simpson, J., Potluri, S., Howard, D., Liang, Y., Paumi, C. M., Mukherjee, S., Crane, P., Younkin, S., Fardo, D. W., and Estus, S.,
“Genetics of CD33 in Alzheimer's disease and acute myeloid leukemia.”,
Hum Mol Genet, vol. 24, no. 12, pp. 3557-70, 2015.
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“Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans.”,
JAMA, vol. 309, no. 14, pp. 1483-92, 2013.
G. W. Beecham, Hamilton, K., Naj, A. C., Martin, E. R., Huentelman, M., Myers, A. J., Corneveaux, J. J., Hardy, J., Vonsattel, J. - P., Younkin, S. G., Bennett, D. A., De Jager, P. L., Larson, E. B., Crane, P. K., M Kamboh, I., Kofler, J. K., Mash, D. C., Duque, L., Gilbert, J. R., Gwirtsman, H., Buxbaum, J. D., Kramer, P., Dickson, D. W., Farrer, L. A., Frosch, M. P., Ghetti, B., Haines, J. L., Hyman, B. T., Kukull, W. A., Mayeux, R. P., Pericak-Vance, M. A., Schneider, J. A., Trojanowski, J. Q., Reiman, E. M., Schellenberg, G. D., and Montine, T. J.,
“Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.”,
PLoS Genet, vol. 10, no. 9, p. e1004606, 2014.
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“Genetic association between endothelial nitric oxide synthase and Alzheimer disease.”,
Clin Genet, vol. 70, no. 1, pp. 49-56, 2006.
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“The executive prominent/memory prominent spectrum in Alzheimer's disease is highly heritable.”,
Neurobiol Aging, vol. 41, pp. 115-121, 2016.
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Cell, vol. 153, no. 3, pp. 707-20, 2013.
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“Age-at-onset linkage analysis in Caribbean Hispanics with familial late-onset Alzheimer's disease.”,
Neurogenetics, vol. 9, no. 1, pp. 51-60, 2008.
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“A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease.”,
Nat Neurosci, vol. 20, no. 8, pp. 1052-1061, 2017.
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“Lewy body pathology is a frequent co-pathology in familial Alzheimer's disease.”,
Acta Neuropathol, vol. 105, no. 5, pp. 484-8, 2003.
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“Glutathione S-transferase omega-1 modifies age-at-onset of Alzheimer disease and Parkinson disease.”,
Hum Mol Genet, vol. 12, no. 24, pp. 3259-67, 2003.
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Curr Alzheimer Res, vol. 9, no. 6, pp. 646-63, 2012.
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“A novel age-informed approach for genetic association analysis in Alzheimer's disease.”,
Alzheimers Res Ther, vol. 13, no. 1, p. 72, 2021.
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J. H. Lee, Cheng, R., Graff-Radford, N., Foroud, T., and Mayeux, R.,
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PLoS Genet, vol. 13, no. 11, p. e1007045, 2017.
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