Overview and findings from the rush Memory and Aging Project.

TitleOverview and findings from the rush Memory and Aging Project.
Publication TypeJournal Article
Year of Publication2012
AuthorsBennett, DA, Schneider, JA, Buchman, AS, Barnes, LL, Boyle, PA, Wilson, RS
JournalCurr Alzheimer Res
Volume9
Issue6
Pagination646-63
Date Published2012 Jul
ISSN1875-5828
KeywordsAging, Alzheimer Disease, Brain, Cognition, Cognition Disorders, Dementia, Humans, Memory, Neuropsychological Tests, Research Design
Abstract

The Memory and Aging Project is a longitudinal, epidemiologic clinical-pathologic cohort study of common chronic conditions of aging with an emphasis on decline in cognitive and motor function and risk of Alzheimer's disease (AD). In this manuscript, we first summarize the study design and methods. Then, we present data on: (1) the relation of motor function to cognition, disability, and death; (2) the relation of risk factors to cognitive and motor outcomes, disability and death; (3) the relation of neuropathologic indices to cognitive outcomes; (4) the relation of risk factors to neuropathologic indices; and (5) additional study findings. The findings are discussed and contextualized.

Alternate JournalCurr Alzheimer Res
PubMed ID22471867
PubMed Central IDPMC3439198
Grant ListR01AG33678 / AG / NIA NIH HHS / United States
R01AG24871 / AG / NIA NIH HHS / United States
R01 AG024480 / AG / NIA NIH HHS / United States
R21AG30765 / AG / NIA NIH HHS / United States
R01 AG024871 / AG / NIA NIH HHS / United States
R21 AG030765 / AG / NIA NIH HHS / United States
R01AG26916 / AG / NIA NIH HHS / United States
R01 AG017917 / AG / NIA NIH HHS / United States
R01AG17917 / AG / NIA NIH HHS / United States
R01 AG033678 / AG / NIA NIH HHS / United States
K23AG23040 / AG / NIA NIH HHS / United States
R01AG22018 / AG / NIA NIH HHS / United States
R01AG15819 / AG / NIA NIH HHS / United States
R01 AG022018 / AG / NIA NIH HHS / United States
R01 AG034374 / AG / NIA NIH HHS / United States
K23 AG023040 / AG / NIA NIH HHS / United States
R01AG34374 / AG / NIA NIH HHS / United States
R01AG24480 / AG / NIA NIH HHS / United States
R01 AG026916 / AG / NIA NIH HHS / United States
R01 AG015819 / AG / NIA NIH HHS / United States