Dataset

NG00020 - NIA-LOAD GWAS

Overview

The goal of the National Institute on Aging Genetics Initiative for Late-Onset Alzheimer's Disease (NIA-LOAD) is to identify and recruit families with two or more siblings with the late-onset form of Alzheimer's disease and a cohort of unrelated, non-demented controls similar in age and ethnic background, and to make the samples, the clinical and genotyping data and preliminary analyses available to qualified investigators world-wide.

Genotyping done by the Center for Inherited Disease Research (CIDR) was performed using the Illumina Infinium II assay protocol with hybridization to Illumina Human 610Quadv1_B Beadchips. This genotyping represents the largest collection of families ever assembled with Alzheimer's disease combining the NIA-LOAD Genetics Initiative Multiplex Family Study, the National Cell Repository for Alzheimer's Disease (NCRAD) with additional controls from the University of Kentucky.

Molecular Data Type

Type

Disease

AD
Submission date: 
8/1/2012
Samples

Case/Control Dataset-

Cases- 993
Controls- 884

Family Dataset- 9,396

Phenotypes
Markers

Case/Control Study- 585,201
Family Study- 620,901

Platform
PI Information