Aged
I. Broce, Karch, C. M., Wen, N., Fan, C. C., Wang, Y., Tan, C. Hong, Kouri, N., Ross, O. A., Höglinger, G. U., Müller, U., Hardy, J., Momeni, P., Hess, C. P., Dillon, W. P., Miller, Z. A., Bonham, L. W., Rabinovici, G. D., Rosen, H. J., Schellenberg, G. D., Franke, A., Karlsen, T. H., Veldink, J. H., Ferrari, R., Yokoyama, J. S., Miller, B. L., Andreassen, O. A., Dale, A. M., Desikan, R. S., and Sugrue, L. P.,
“Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies.”,
PLoS Med, vol. 15, no. 1, p. e1002487, 2018.
R. S. Desikan, Fan, C. Chieh, Wang, Y., Schork, A. J., Cabral, H. J., L Cupples, A., Thompson, W. K., Besser, L., Kukull, W. A., Holland, D., Chen, C. - H., Brewer, J. B., Karow, D. S., Kauppi, K., Witoelar, A., Karch, C. M., Bonham, L. W., Yokoyama, J. S., Rosen, H. J., Miller, B. L., Dillon, W. P., Wilson, D. M., Hess, C. P., Pericak-Vance, M., Haines, J. L., Farrer, L. A., Mayeux, R., Hardy, J., Goate, A. M., Hyman, B. T., Schellenberg, G. D., McEvoy, L. K., Andreassen, O. A., and Dale, A. M.,
“Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score.”,
PLoS Med, vol. 14, no. 3, p. e1002258, 2017.
Aged, 80 and over
R. S. Desikan, Fan, C. Chieh, Wang, Y., Schork, A. J., Cabral, H. J., L Cupples, A., Thompson, W. K., Besser, L., Kukull, W. A., Holland, D., Chen, C. - H., Brewer, J. B., Karow, D. S., Kauppi, K., Witoelar, A., Karch, C. M., Bonham, L. W., Yokoyama, J. S., Rosen, H. J., Miller, B. L., Dillon, W. P., Wilson, D. M., Hess, C. P., Pericak-Vance, M., Haines, J. L., Farrer, L. A., Mayeux, R., Hardy, J., Goate, A. M., Hyman, B. T., Schellenberg, G. D., McEvoy, L. K., Andreassen, O. A., and Dale, A. M.,
“Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score.”,
PLoS Med, vol. 14, no. 3, p. e1002258, 2017.
Alzheimer Disease
R. S. Desikan, Fan, C. Chieh, Wang, Y., Schork, A. J., Cabral, H. J., L Cupples, A., Thompson, W. K., Besser, L., Kukull, W. A., Holland, D., Chen, C. - H., Brewer, J. B., Karow, D. S., Kauppi, K., Witoelar, A., Karch, C. M., Bonham, L. W., Yokoyama, J. S., Rosen, H. J., Miller, B. L., Dillon, W. P., Wilson, D. M., Hess, C. P., Pericak-Vance, M., Haines, J. L., Farrer, L. A., Mayeux, R., Hardy, J., Goate, A. M., Hyman, B. T., Schellenberg, G. D., McEvoy, L. K., Andreassen, O. A., and Dale, A. M.,
“Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score.”,
PLoS Med, vol. 14, no. 3, p. e1002258, 2017.
Apolipoproteins E
R. S. Desikan, Fan, C. Chieh, Wang, Y., Schork, A. J., Cabral, H. J., L Cupples, A., Thompson, W. K., Besser, L., Kukull, W. A., Holland, D., Chen, C. - H., Brewer, J. B., Karow, D. S., Kauppi, K., Witoelar, A., Karch, C. M., Bonham, L. W., Yokoyama, J. S., Rosen, H. J., Miller, B. L., Dillon, W. P., Wilson, D. M., Hess, C. P., Pericak-Vance, M., Haines, J. L., Farrer, L. A., Mayeux, R., Hardy, J., Goate, A. M., Hyman, B. T., Schellenberg, G. D., McEvoy, L. K., Andreassen, O. A., and Dale, A. M.,
“Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score.”,
PLoS Med, vol. 14, no. 3, p. e1002258, 2017.
Female
R. S. Desikan, Fan, C. Chieh, Wang, Y., Schork, A. J., Cabral, H. J., L Cupples, A., Thompson, W. K., Besser, L., Kukull, W. A., Holland, D., Chen, C. - H., Brewer, J. B., Karow, D. S., Kauppi, K., Witoelar, A., Karch, C. M., Bonham, L. W., Yokoyama, J. S., Rosen, H. J., Miller, B. L., Dillon, W. P., Wilson, D. M., Hess, C. P., Pericak-Vance, M., Haines, J. L., Farrer, L. A., Mayeux, R., Hardy, J., Goate, A. M., Hyman, B. T., Schellenberg, G. D., McEvoy, L. K., Andreassen, O. A., and Dale, A. M.,
“Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score.”,
PLoS Med, vol. 14, no. 3, p. e1002258, 2017.
Frontotemporal Dementia
I. Broce, Karch, C. M., Wen, N., Fan, C. C., Wang, Y., Tan, C. Hong, Kouri, N., Ross, O. A., Höglinger, G. U., Müller, U., Hardy, J., Momeni, P., Hess, C. P., Dillon, W. P., Miller, Z. A., Bonham, L. W., Rabinovici, G. D., Rosen, H. J., Schellenberg, G. D., Franke, A., Karlsen, T. H., Veldink, J. H., Ferrari, R., Yokoyama, J. S., Miller, B. L., Andreassen, O. A., Dale, A. M., Desikan, R. S., and Sugrue, L. P.,
“Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies.”,
PLoS Med, vol. 15, no. 1, p. e1002487, 2018.
Genetic Predisposition to Disease
I. Broce, Karch, C. M., Wen, N., Fan, C. C., Wang, Y., Tan, C. Hong, Kouri, N., Ross, O. A., Höglinger, G. U., Müller, U., Hardy, J., Momeni, P., Hess, C. P., Dillon, W. P., Miller, Z. A., Bonham, L. W., Rabinovici, G. D., Rosen, H. J., Schellenberg, G. D., Franke, A., Karlsen, T. H., Veldink, J. H., Ferrari, R., Yokoyama, J. S., Miller, B. L., Andreassen, O. A., Dale, A. M., Desikan, R. S., and Sugrue, L. P.,
“Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies.”,
PLoS Med, vol. 15, no. 1, p. e1002487, 2018.
Genome-Wide Association Study
I. Broce, Karch, C. M., Wen, N., Fan, C. C., Wang, Y., Tan, C. Hong, Kouri, N., Ross, O. A., Höglinger, G. U., Müller, U., Hardy, J., Momeni, P., Hess, C. P., Dillon, W. P., Miller, Z. A., Bonham, L. W., Rabinovici, G. D., Rosen, H. J., Schellenberg, G. D., Franke, A., Karlsen, T. H., Veldink, J. H., Ferrari, R., Yokoyama, J. S., Miller, B. L., Andreassen, O. A., Dale, A. M., Desikan, R. S., and Sugrue, L. P.,
“Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies.”,
PLoS Med, vol. 15, no. 1, p. e1002487, 2018.
Genotype
R. S. Desikan, Fan, C. Chieh, Wang, Y., Schork, A. J., Cabral, H. J., L Cupples, A., Thompson, W. K., Besser, L., Kukull, W. A., Holland, D., Chen, C. - H., Brewer, J. B., Karow, D. S., Kauppi, K., Witoelar, A., Karch, C. M., Bonham, L. W., Yokoyama, J. S., Rosen, H. J., Miller, B. L., Dillon, W. P., Wilson, D. M., Hess, C. P., Pericak-Vance, M., Haines, J. L., Farrer, L. A., Mayeux, R., Hardy, J., Goate, A. M., Hyman, B. T., Schellenberg, G. D., McEvoy, L. K., Andreassen, O. A., and Dale, A. M.,
“Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score.”,
PLoS Med, vol. 14, no. 3, p. e1002258, 2017.
Geriatric Assessment
R. S. Desikan, Fan, C. Chieh, Wang, Y., Schork, A. J., Cabral, H. J., L Cupples, A., Thompson, W. K., Besser, L., Kukull, W. A., Holland, D., Chen, C. - H., Brewer, J. B., Karow, D. S., Kauppi, K., Witoelar, A., Karch, C. M., Bonham, L. W., Yokoyama, J. S., Rosen, H. J., Miller, B. L., Dillon, W. P., Wilson, D. M., Hess, C. P., Pericak-Vance, M., Haines, J. L., Farrer, L. A., Mayeux, R., Hardy, J., Goate, A. M., Hyman, B. T., Schellenberg, G. D., McEvoy, L. K., Andreassen, O. A., and Dale, A. M.,
“Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score.”,
PLoS Med, vol. 14, no. 3, p. e1002258, 2017.
Humans
I. Broce, Karch, C. M., Wen, N., Fan, C. C., Wang, Y., Tan, C. Hong, Kouri, N., Ross, O. A., Höglinger, G. U., Müller, U., Hardy, J., Momeni, P., Hess, C. P., Dillon, W. P., Miller, Z. A., Bonham, L. W., Rabinovici, G. D., Rosen, H. J., Schellenberg, G. D., Franke, A., Karlsen, T. H., Veldink, J. H., Ferrari, R., Yokoyama, J. S., Miller, B. L., Andreassen, O. A., Dale, A. M., Desikan, R. S., and Sugrue, L. P.,
“Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies.”,
PLoS Med, vol. 15, no. 1, p. e1002487, 2018.
R. S. Desikan, Fan, C. Chieh, Wang, Y., Schork, A. J., Cabral, H. J., L Cupples, A., Thompson, W. K., Besser, L., Kukull, W. A., Holland, D., Chen, C. - H., Brewer, J. B., Karow, D. S., Kauppi, K., Witoelar, A., Karch, C. M., Bonham, L. W., Yokoyama, J. S., Rosen, H. J., Miller, B. L., Dillon, W. P., Wilson, D. M., Hess, C. P., Pericak-Vance, M., Haines, J. L., Farrer, L. A., Mayeux, R., Hardy, J., Goate, A. M., Hyman, B. T., Schellenberg, G. D., McEvoy, L. K., Andreassen, O. A., and Dale, A. M.,
“Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score.”,
PLoS Med, vol. 14, no. 3, p. e1002258, 2017.
Longitudinal Studies
R. S. Desikan, Fan, C. Chieh, Wang, Y., Schork, A. J., Cabral, H. J., L Cupples, A., Thompson, W. K., Besser, L., Kukull, W. A., Holland, D., Chen, C. - H., Brewer, J. B., Karow, D. S., Kauppi, K., Witoelar, A., Karch, C. M., Bonham, L. W., Yokoyama, J. S., Rosen, H. J., Miller, B. L., Dillon, W. P., Wilson, D. M., Hess, C. P., Pericak-Vance, M., Haines, J. L., Farrer, L. A., Mayeux, R., Hardy, J., Goate, A. M., Hyman, B. T., Schellenberg, G. D., McEvoy, L. K., Andreassen, O. A., and Dale, A. M.,
“Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score.”,
PLoS Med, vol. 14, no. 3, p. e1002258, 2017.
Male
R. S. Desikan, Fan, C. Chieh, Wang, Y., Schork, A. J., Cabral, H. J., L Cupples, A., Thompson, W. K., Besser, L., Kukull, W. A., Holland, D., Chen, C. - H., Brewer, J. B., Karow, D. S., Kauppi, K., Witoelar, A., Karch, C. M., Bonham, L. W., Yokoyama, J. S., Rosen, H. J., Miller, B. L., Dillon, W. P., Wilson, D. M., Hess, C. P., Pericak-Vance, M., Haines, J. L., Farrer, L. A., Mayeux, R., Hardy, J., Goate, A. M., Hyman, B. T., Schellenberg, G. D., McEvoy, L. K., Andreassen, O. A., and Dale, A. M.,
“Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score.”,
PLoS Med, vol. 14, no. 3, p. e1002258, 2017.
Middle Aged
I. Broce, Karch, C. M., Wen, N., Fan, C. C., Wang, Y., Tan, C. Hong, Kouri, N., Ross, O. A., Höglinger, G. U., Müller, U., Hardy, J., Momeni, P., Hess, C. P., Dillon, W. P., Miller, Z. A., Bonham, L. W., Rabinovici, G. D., Rosen, H. J., Schellenberg, G. D., Franke, A., Karlsen, T. H., Veldink, J. H., Ferrari, R., Yokoyama, J. S., Miller, B. L., Andreassen, O. A., Dale, A. M., Desikan, R. S., and Sugrue, L. P.,
“Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies.”,
PLoS Med, vol. 15, no. 1, p. e1002487, 2018.
R. S. Desikan, Fan, C. Chieh, Wang, Y., Schork, A. J., Cabral, H. J., L Cupples, A., Thompson, W. K., Besser, L., Kukull, W. A., Holland, D., Chen, C. - H., Brewer, J. B., Karow, D. S., Kauppi, K., Witoelar, A., Karch, C. M., Bonham, L. W., Yokoyama, J. S., Rosen, H. J., Miller, B. L., Dillon, W. P., Wilson, D. M., Hess, C. P., Pericak-Vance, M., Haines, J. L., Farrer, L. A., Mayeux, R., Hardy, J., Goate, A. M., Hyman, B. T., Schellenberg, G. D., McEvoy, L. K., Andreassen, O. A., and Dale, A. M.,
“Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score.”,
PLoS Med, vol. 14, no. 3, p. e1002258, 2017.
Multifactorial Inheritance
R. S. Desikan, Fan, C. Chieh, Wang, Y., Schork, A. J., Cabral, H. J., L Cupples, A., Thompson, W. K., Besser, L., Kukull, W. A., Holland, D., Chen, C. - H., Brewer, J. B., Karow, D. S., Kauppi, K., Witoelar, A., Karch, C. M., Bonham, L. W., Yokoyama, J. S., Rosen, H. J., Miller, B. L., Dillon, W. P., Wilson, D. M., Hess, C. P., Pericak-Vance, M., Haines, J. L., Farrer, L. A., Mayeux, R., Hardy, J., Goate, A. M., Hyman, B. T., Schellenberg, G. D., McEvoy, L. K., Andreassen, O. A., and Dale, A. M.,
“Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score.”,
PLoS Med, vol. 14, no. 3, p. e1002258, 2017.
Polymorphism, Single Nucleotide
I. Broce, Karch, C. M., Wen, N., Fan, C. C., Wang, Y., Tan, C. Hong, Kouri, N., Ross, O. A., Höglinger, G. U., Müller, U., Hardy, J., Momeni, P., Hess, C. P., Dillon, W. P., Miller, Z. A., Bonham, L. W., Rabinovici, G. D., Rosen, H. J., Schellenberg, G. D., Franke, A., Karlsen, T. H., Veldink, J. H., Ferrari, R., Yokoyama, J. S., Miller, B. L., Andreassen, O. A., Dale, A. M., Desikan, R. S., and Sugrue, L. P.,
“Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies.”,
PLoS Med, vol. 15, no. 1, p. e1002487, 2018.
R. S. Desikan, Fan, C. Chieh, Wang, Y., Schork, A. J., Cabral, H. J., L Cupples, A., Thompson, W. K., Besser, L., Kukull, W. A., Holland, D., Chen, C. - H., Brewer, J. B., Karow, D. S., Kauppi, K., Witoelar, A., Karch, C. M., Bonham, L. W., Yokoyama, J. S., Rosen, H. J., Miller, B. L., Dillon, W. P., Wilson, D. M., Hess, C. P., Pericak-Vance, M., Haines, J. L., Farrer, L. A., Mayeux, R., Hardy, J., Goate, A. M., Hyman, B. T., Schellenberg, G. D., McEvoy, L. K., Andreassen, O. A., and Dale, A. M.,
“Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score.”,
PLoS Med, vol. 14, no. 3, p. e1002258, 2017.
United States
R. S. Desikan, Fan, C. Chieh, Wang, Y., Schork, A. J., Cabral, H. J., L Cupples, A., Thompson, W. K., Besser, L., Kukull, W. A., Holland, D., Chen, C. - H., Brewer, J. B., Karow, D. S., Kauppi, K., Witoelar, A., Karch, C. M., Bonham, L. W., Yokoyama, J. S., Rosen, H. J., Miller, B. L., Dillon, W. P., Wilson, D. M., Hess, C. P., Pericak-Vance, M., Haines, J. L., Farrer, L. A., Mayeux, R., Hardy, J., Goate, A. M., Hyman, B. T., Schellenberg, G. D., McEvoy, L. K., Andreassen, O. A., and Dale, A. M.,
“Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score.”,
PLoS Med, vol. 14, no. 3, p. e1002258, 2017.