Aged
R. S. Desikan, Schork, A. J., Wang, Y., Witoelar, A., Sharma, M., McEvoy, L. K., Holland, D., Brewer, J. B., Chen, C. - H., Thompson, W. K., Harold, D., Williams, J., Owen, M. J., O'Donovan, M. C., Pericak-Vance, M. A., Mayeux, R., Haines, J. L., Farrer, L. A., Schellenberg, G. D., Heutink, P., Singleton, A. B., Brice, A., Wood, N. W., Hardy, J., Martinez, M., Choi, S. H., DeStefano, A., Ikram, M. A., Bis, J. C., Smith, A., Fitzpatrick, A. L., Launer, L., van Duijn, C., Seshadri, S., Ulstein, I. D., Aarsland, D., Fladby, T., Djurovic, S., Hyman, B. T., Snaedal, J., Stefansson, H., Stefansson, K., Gasser, T., Andreassen, O. A., and Dale, A. M.,
“Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus.”,
Mol Psychiatry, vol. 20, no. 12, pp. 1588-95, 2015.
Aged, 80 and over
R. S. Desikan, Schork, A. J., Wang, Y., Witoelar, A., Sharma, M., McEvoy, L. K., Holland, D., Brewer, J. B., Chen, C. - H., Thompson, W. K., Harold, D., Williams, J., Owen, M. J., O'Donovan, M. C., Pericak-Vance, M. A., Mayeux, R., Haines, J. L., Farrer, L. A., Schellenberg, G. D., Heutink, P., Singleton, A. B., Brice, A., Wood, N. W., Hardy, J., Martinez, M., Choi, S. H., DeStefano, A., Ikram, M. A., Bis, J. C., Smith, A., Fitzpatrick, A. L., Launer, L., van Duijn, C., Seshadri, S., Ulstein, I. D., Aarsland, D., Fladby, T., Djurovic, S., Hyman, B. T., Snaedal, J., Stefansson, H., Stefansson, K., Gasser, T., Andreassen, O. A., and Dale, A. M.,
“Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus.”,
Mol Psychiatry, vol. 20, no. 12, pp. 1588-95, 2015.
Alleles
R. S. Desikan, Schork, A. J., Wang, Y., Witoelar, A., Sharma, M., McEvoy, L. K., Holland, D., Brewer, J. B., Chen, C. - H., Thompson, W. K., Harold, D., Williams, J., Owen, M. J., O'Donovan, M. C., Pericak-Vance, M. A., Mayeux, R., Haines, J. L., Farrer, L. A., Schellenberg, G. D., Heutink, P., Singleton, A. B., Brice, A., Wood, N. W., Hardy, J., Martinez, M., Choi, S. H., DeStefano, A., Ikram, M. A., Bis, J. C., Smith, A., Fitzpatrick, A. L., Launer, L., van Duijn, C., Seshadri, S., Ulstein, I. D., Aarsland, D., Fladby, T., Djurovic, S., Hyman, B. T., Snaedal, J., Stefansson, H., Stefansson, K., Gasser, T., Andreassen, O. A., and Dale, A. M.,
“Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus.”,
Mol Psychiatry, vol. 20, no. 12, pp. 1588-95, 2015.
Alzheimer Disease
R. S. Desikan, Schork, A. J., Wang, Y., Witoelar, A., Sharma, M., McEvoy, L. K., Holland, D., Brewer, J. B., Chen, C. - H., Thompson, W. K., Harold, D., Williams, J., Owen, M. J., O'Donovan, M. C., Pericak-Vance, M. A., Mayeux, R., Haines, J. L., Farrer, L. A., Schellenberg, G. D., Heutink, P., Singleton, A. B., Brice, A., Wood, N. W., Hardy, J., Martinez, M., Choi, S. H., DeStefano, A., Ikram, M. A., Bis, J. C., Smith, A., Fitzpatrick, A. L., Launer, L., van Duijn, C., Seshadri, S., Ulstein, I. D., Aarsland, D., Fladby, T., Djurovic, S., Hyman, B. T., Snaedal, J., Stefansson, H., Stefansson, K., Gasser, T., Andreassen, O. A., and Dale, A. M.,
“Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus.”,
Mol Psychiatry, vol. 20, no. 12, pp. 1588-95, 2015.
Apolipoproteins E
R. S. Desikan, Schork, A. J., Wang, Y., Witoelar, A., Sharma, M., McEvoy, L. K., Holland, D., Brewer, J. B., Chen, C. - H., Thompson, W. K., Harold, D., Williams, J., Owen, M. J., O'Donovan, M. C., Pericak-Vance, M. A., Mayeux, R., Haines, J. L., Farrer, L. A., Schellenberg, G. D., Heutink, P., Singleton, A. B., Brice, A., Wood, N. W., Hardy, J., Martinez, M., Choi, S. H., DeStefano, A., Ikram, M. A., Bis, J. C., Smith, A., Fitzpatrick, A. L., Launer, L., van Duijn, C., Seshadri, S., Ulstein, I. D., Aarsland, D., Fladby, T., Djurovic, S., Hyman, B. T., Snaedal, J., Stefansson, H., Stefansson, K., Gasser, T., Andreassen, O. A., and Dale, A. M.,
“Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus.”,
Mol Psychiatry, vol. 20, no. 12, pp. 1588-95, 2015.
Brain
R. S. Desikan, Schork, A. J., Wang, Y., Witoelar, A., Sharma, M., McEvoy, L. K., Holland, D., Brewer, J. B., Chen, C. - H., Thompson, W. K., Harold, D., Williams, J., Owen, M. J., O'Donovan, M. C., Pericak-Vance, M. A., Mayeux, R., Haines, J. L., Farrer, L. A., Schellenberg, G. D., Heutink, P., Singleton, A. B., Brice, A., Wood, N. W., Hardy, J., Martinez, M., Choi, S. H., DeStefano, A., Ikram, M. A., Bis, J. C., Smith, A., Fitzpatrick, A. L., Launer, L., van Duijn, C., Seshadri, S., Ulstein, I. D., Aarsland, D., Fladby, T., Djurovic, S., Hyman, B. T., Snaedal, J., Stefansson, H., Stefansson, K., Gasser, T., Andreassen, O. A., and Dale, A. M.,
“Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus.”,
Mol Psychiatry, vol. 20, no. 12, pp. 1588-95, 2015.
Chromosomes, Human, Pair 17
R. S. Desikan, Schork, A. J., Wang, Y., Witoelar, A., Sharma, M., McEvoy, L. K., Holland, D., Brewer, J. B., Chen, C. - H., Thompson, W. K., Harold, D., Williams, J., Owen, M. J., O'Donovan, M. C., Pericak-Vance, M. A., Mayeux, R., Haines, J. L., Farrer, L. A., Schellenberg, G. D., Heutink, P., Singleton, A. B., Brice, A., Wood, N. W., Hardy, J., Martinez, M., Choi, S. H., DeStefano, A., Ikram, M. A., Bis, J. C., Smith, A., Fitzpatrick, A. L., Launer, L., van Duijn, C., Seshadri, S., Ulstein, I. D., Aarsland, D., Fladby, T., Djurovic, S., Hyman, B. T., Snaedal, J., Stefansson, H., Stefansson, K., Gasser, T., Andreassen, O. A., and Dale, A. M.,
“Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus.”,
Mol Psychiatry, vol. 20, no. 12, pp. 1588-95, 2015.
Female
R. S. Desikan, Schork, A. J., Wang, Y., Witoelar, A., Sharma, M., McEvoy, L. K., Holland, D., Brewer, J. B., Chen, C. - H., Thompson, W. K., Harold, D., Williams, J., Owen, M. J., O'Donovan, M. C., Pericak-Vance, M. A., Mayeux, R., Haines, J. L., Farrer, L. A., Schellenberg, G. D., Heutink, P., Singleton, A. B., Brice, A., Wood, N. W., Hardy, J., Martinez, M., Choi, S. H., DeStefano, A., Ikram, M. A., Bis, J. C., Smith, A., Fitzpatrick, A. L., Launer, L., van Duijn, C., Seshadri, S., Ulstein, I. D., Aarsland, D., Fladby, T., Djurovic, S., Hyman, B. T., Snaedal, J., Stefansson, H., Stefansson, K., Gasser, T., Andreassen, O. A., and Dale, A. M.,
“Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus.”,
Mol Psychiatry, vol. 20, no. 12, pp. 1588-95, 2015.
Genetic Loci
R. S. Desikan, Schork, A. J., Wang, Y., Witoelar, A., Sharma, M., McEvoy, L. K., Holland, D., Brewer, J. B., Chen, C. - H., Thompson, W. K., Harold, D., Williams, J., Owen, M. J., O'Donovan, M. C., Pericak-Vance, M. A., Mayeux, R., Haines, J. L., Farrer, L. A., Schellenberg, G. D., Heutink, P., Singleton, A. B., Brice, A., Wood, N. W., Hardy, J., Martinez, M., Choi, S. H., DeStefano, A., Ikram, M. A., Bis, J. C., Smith, A., Fitzpatrick, A. L., Launer, L., van Duijn, C., Seshadri, S., Ulstein, I. D., Aarsland, D., Fladby, T., Djurovic, S., Hyman, B. T., Snaedal, J., Stefansson, H., Stefansson, K., Gasser, T., Andreassen, O. A., and Dale, A. M.,
“Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus.”,
Mol Psychiatry, vol. 20, no. 12, pp. 1588-95, 2015.
Genetic Pleiotropy
R. S. Desikan, Schork, A. J., Wang, Y., Witoelar, A., Sharma, M., McEvoy, L. K., Holland, D., Brewer, J. B., Chen, C. - H., Thompson, W. K., Harold, D., Williams, J., Owen, M. J., O'Donovan, M. C., Pericak-Vance, M. A., Mayeux, R., Haines, J. L., Farrer, L. A., Schellenberg, G. D., Heutink, P., Singleton, A. B., Brice, A., Wood, N. W., Hardy, J., Martinez, M., Choi, S. H., DeStefano, A., Ikram, M. A., Bis, J. C., Smith, A., Fitzpatrick, A. L., Launer, L., van Duijn, C., Seshadri, S., Ulstein, I. D., Aarsland, D., Fladby, T., Djurovic, S., Hyman, B. T., Snaedal, J., Stefansson, H., Stefansson, K., Gasser, T., Andreassen, O. A., and Dale, A. M.,
“Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus.”,
Mol Psychiatry, vol. 20, no. 12, pp. 1588-95, 2015.
Genome-Wide Association Study
R. S. Desikan, Schork, A. J., Wang, Y., Witoelar, A., Sharma, M., McEvoy, L. K., Holland, D., Brewer, J. B., Chen, C. - H., Thompson, W. K., Harold, D., Williams, J., Owen, M. J., O'Donovan, M. C., Pericak-Vance, M. A., Mayeux, R., Haines, J. L., Farrer, L. A., Schellenberg, G. D., Heutink, P., Singleton, A. B., Brice, A., Wood, N. W., Hardy, J., Martinez, M., Choi, S. H., DeStefano, A., Ikram, M. A., Bis, J. C., Smith, A., Fitzpatrick, A. L., Launer, L., van Duijn, C., Seshadri, S., Ulstein, I. D., Aarsland, D., Fladby, T., Djurovic, S., Hyman, B. T., Snaedal, J., Stefansson, H., Stefansson, K., Gasser, T., Andreassen, O. A., and Dale, A. M.,
“Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus.”,
Mol Psychiatry, vol. 20, no. 12, pp. 1588-95, 2015.
Humans
R. S. Desikan, Schork, A. J., Wang, Y., Witoelar, A., Sharma, M., McEvoy, L. K., Holland, D., Brewer, J. B., Chen, C. - H., Thompson, W. K., Harold, D., Williams, J., Owen, M. J., O'Donovan, M. C., Pericak-Vance, M. A., Mayeux, R., Haines, J. L., Farrer, L. A., Schellenberg, G. D., Heutink, P., Singleton, A. B., Brice, A., Wood, N. W., Hardy, J., Martinez, M., Choi, S. H., DeStefano, A., Ikram, M. A., Bis, J. C., Smith, A., Fitzpatrick, A. L., Launer, L., van Duijn, C., Seshadri, S., Ulstein, I. D., Aarsland, D., Fladby, T., Djurovic, S., Hyman, B. T., Snaedal, J., Stefansson, H., Stefansson, K., Gasser, T., Andreassen, O. A., and Dale, A. M.,
“Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus.”,
Mol Psychiatry, vol. 20, no. 12, pp. 1588-95, 2015.
Male
R. S. Desikan, Schork, A. J., Wang, Y., Witoelar, A., Sharma, M., McEvoy, L. K., Holland, D., Brewer, J. B., Chen, C. - H., Thompson, W. K., Harold, D., Williams, J., Owen, M. J., O'Donovan, M. C., Pericak-Vance, M. A., Mayeux, R., Haines, J. L., Farrer, L. A., Schellenberg, G. D., Heutink, P., Singleton, A. B., Brice, A., Wood, N. W., Hardy, J., Martinez, M., Choi, S. H., DeStefano, A., Ikram, M. A., Bis, J. C., Smith, A., Fitzpatrick, A. L., Launer, L., van Duijn, C., Seshadri, S., Ulstein, I. D., Aarsland, D., Fladby, T., Djurovic, S., Hyman, B. T., Snaedal, J., Stefansson, H., Stefansson, K., Gasser, T., Andreassen, O. A., and Dale, A. M.,
“Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus.”,
Mol Psychiatry, vol. 20, no. 12, pp. 1588-95, 2015.
Middle Aged
R. S. Desikan, Schork, A. J., Wang, Y., Witoelar, A., Sharma, M., McEvoy, L. K., Holland, D., Brewer, J. B., Chen, C. - H., Thompson, W. K., Harold, D., Williams, J., Owen, M. J., O'Donovan, M. C., Pericak-Vance, M. A., Mayeux, R., Haines, J. L., Farrer, L. A., Schellenberg, G. D., Heutink, P., Singleton, A. B., Brice, A., Wood, N. W., Hardy, J., Martinez, M., Choi, S. H., DeStefano, A., Ikram, M. A., Bis, J. C., Smith, A., Fitzpatrick, A. L., Launer, L., van Duijn, C., Seshadri, S., Ulstein, I. D., Aarsland, D., Fladby, T., Djurovic, S., Hyman, B. T., Snaedal, J., Stefansson, H., Stefansson, K., Gasser, T., Andreassen, O. A., and Dale, A. M.,
“Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus.”,
Mol Psychiatry, vol. 20, no. 12, pp. 1588-95, 2015.
Parkinson Disease
R. S. Desikan, Schork, A. J., Wang, Y., Witoelar, A., Sharma, M., McEvoy, L. K., Holland, D., Brewer, J. B., Chen, C. - H., Thompson, W. K., Harold, D., Williams, J., Owen, M. J., O'Donovan, M. C., Pericak-Vance, M. A., Mayeux, R., Haines, J. L., Farrer, L. A., Schellenberg, G. D., Heutink, P., Singleton, A. B., Brice, A., Wood, N. W., Hardy, J., Martinez, M., Choi, S. H., DeStefano, A., Ikram, M. A., Bis, J. C., Smith, A., Fitzpatrick, A. L., Launer, L., van Duijn, C., Seshadri, S., Ulstein, I. D., Aarsland, D., Fladby, T., Djurovic, S., Hyman, B. T., Snaedal, J., Stefansson, H., Stefansson, K., Gasser, T., Andreassen, O. A., and Dale, A. M.,
“Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus.”,
Mol Psychiatry, vol. 20, no. 12, pp. 1588-95, 2015.
Polymorphism, Single Nucleotide
R. S. Desikan, Schork, A. J., Wang, Y., Witoelar, A., Sharma, M., McEvoy, L. K., Holland, D., Brewer, J. B., Chen, C. - H., Thompson, W. K., Harold, D., Williams, J., Owen, M. J., O'Donovan, M. C., Pericak-Vance, M. A., Mayeux, R., Haines, J. L., Farrer, L. A., Schellenberg, G. D., Heutink, P., Singleton, A. B., Brice, A., Wood, N. W., Hardy, J., Martinez, M., Choi, S. H., DeStefano, A., Ikram, M. A., Bis, J. C., Smith, A., Fitzpatrick, A. L., Launer, L., van Duijn, C., Seshadri, S., Ulstein, I. D., Aarsland, D., Fladby, T., Djurovic, S., Hyman, B. T., Snaedal, J., Stefansson, H., Stefansson, K., Gasser, T., Andreassen, O. A., and Dale, A. M.,
“Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus.”,
Mol Psychiatry, vol. 20, no. 12, pp. 1588-95, 2015.
tau Proteins
R. S. Desikan, Schork, A. J., Wang, Y., Witoelar, A., Sharma, M., McEvoy, L. K., Holland, D., Brewer, J. B., Chen, C. - H., Thompson, W. K., Harold, D., Williams, J., Owen, M. J., O'Donovan, M. C., Pericak-Vance, M. A., Mayeux, R., Haines, J. L., Farrer, L. A., Schellenberg, G. D., Heutink, P., Singleton, A. B., Brice, A., Wood, N. W., Hardy, J., Martinez, M., Choi, S. H., DeStefano, A., Ikram, M. A., Bis, J. C., Smith, A., Fitzpatrick, A. L., Launer, L., van Duijn, C., Seshadri, S., Ulstein, I. D., Aarsland, D., Fladby, T., Djurovic, S., Hyman, B. T., Snaedal, J., Stefansson, H., Stefansson, K., Gasser, T., Andreassen, O. A., and Dale, A. M.,
“Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus.”,
Mol Psychiatry, vol. 20, no. 12, pp. 1588-95, 2015.