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M
Mukherjee S
,
Mez J
,
Trittschuh EH
,
Saykin AJ
,
Gibbons LE
,
Fardo DW
,
Wessels M
,
Bauman J
,
Moore M
,
Choi S-E
et al.
. 2020.
Genetic data and cognitively defined late-onset Alzheimer's disease subgroups.
.
Mol Psychiatry. 25(11):2942-2951.
PubMed
N
Nafikov RA
,
Nato AQ
,
Sohi H
,
Wang B
,
Brown L
,
Horimoto AR
,
Vardarajan BN
,
Barral SM
,
Tosto G
,
Mayeux RP
et al.
. 2018.
Analysis of pedigree data in populations with multiple ancestries: Strategies for dealing with admixture in Caribbean Hispanic families from the ADSP.
.
Genet Epidemiol. 42(6):500-515.
PubMed
Naj AC
,
Lin H
,
Vardarajan BN
,
White S
,
Lancour D
,
Ma Y
,
Schmidt M
,
Sun F
,
Butkiewicz M
,
Bush WS
et al.
. 2018.
Quality control and integration of genotypes from two calling pipelines for whole genome sequence data in the Alzheimer's disease sequencing project.
.
Genomics.
PubMed
Neff RA
,
Wang M
,
Vatansever S
,
Guo L
,
Ming C
,
Wang Q
,
Wang E
,
Horgusluoglu-Moloch E
,
Song W-M
,
Li A
et al.
. 2021.
Molecular subtyping of Alzheimer's disease using RNA sequencing data reveals novel mechanisms and targets.
.
Sci Adv. 7(2)
PubMed
Neuner SM
,
Tcw J
,
Goate AM
. 2020.
Genetic architecture of Alzheimer's disease.
.
Neurobiol Dis. 143:104976.
PubMed
Nho K
,
Nudelman K
,
Allen M
,
Hodges A
,
Kim S
,
Risacher SL
,
Apostolova LG
,
Lin K
,
Lunnon K
,
Wang X
et al.
. 2020.
Genome-wide transcriptome analysis identifies novel dysregulated genes implicated in Alzheimer's pathology.
.
Alzheimers Dement. 16(9):1213-1223.
PubMed
Novikova G
,
Kapoor M
,
Tcw J
,
Abud EM
,
Efthymiou AG
,
Chen SX
,
Cheng H
,
Fullard JF
,
Bendl J
,
Liu Y
et al.
. 2021.
Integration of Alzheimer's disease genetics and myeloid genomics identifies disease risk regulatory elements and genes.
.
Nat Commun. 12(1):1610.
PubMed
O
Olive C
,
Ibañez L
,
Farias FHGeraldo
,
Wang F
,
Budde JP
,
Norton JB
,
Gentsch J
,
Morris JC
,
Li Z
,
Dube U
et al.
. 2020.
Examination of the Effect of Rare Variants in TREM2, ABI3, and PLCG2 in LOAD Through Multiple Phenotypes.
.
J Alzheimers Dis. 77(4):1469-1482.
PubMed
Ouellette AR
,
Neuner SM
,
Dumitrescu L
,
Anderson LC
,
Gatti DM
,
Mahoney ER
,
Bubier JA
,
Churchill G
,
Peters L
,
Huentelman MJ
et al.
. 2020.
Cross-Species Analyses Identify Dlgap2 as a Regulator of Age-Related Cognitive Decline and Alzheimer's Dementia.
.
Cell Rep. 32(9):108091.
PubMed
P
Panitch R
,
Hu J
,
Chung J
,
Zhu C
,
Meng G
,
Xia W
,
Bennett DA
,
Lunetta KL
,
Ikezu T
,
Au R
et al.
. 2021.
Integrative brain transcriptome analysis links complement component 4 and HSPA2 to the APOE ε2 protective effect in Alzheimer disease.
.
Mol Psychiatry. 26(10):6054-6064.
PubMed
Pase MP
,
Himali JJ
,
Beiser AS
,
DeCarli C
,
McGrath ER
,
Satizabal CL
,
Aparicio HJ
,
Adams HHH
,
Reiner AP
,
Longstreth WT
et al.
. 2020.
Association of CD14 with incident dementia and markers of brain aging and injury.
.
Neurology. 94(3):e254-e266.
PubMed
Patel D
,
Mez J
,
Vardarajan BN
,
Staley L
,
Chung J
,
Zhang X
,
Farrell JJ
,
Rynkiewicz MJ
,
Cannon-Albright LA
,
Teerlink CC
et al.
. 2019.
Association of Rare Coding Mutations With Alzheimer Disease and Other Dementias Among Adults of European Ancestry.
.
JAMA Netw Open. 2(3):e191350.
PubMed
Patel D
,
Zhang X
,
Farrell JJ
,
Lunetta KL
,
Farrer LA
. 2021.
Set-Based Rare Variant Expression Quantitative Trait Loci in Blood and Brain from Alzheimer Disease Study Participants.
.
Genes (Basel). 12(3)
PubMed
Patel D
,
Zhang X
,
Farrell JJ
,
Chung J
,
Stein TD
,
Lunetta KL
,
Farrer LA
. 2021.
Cell-type-specific expression quantitative trait loci associated with Alzheimer disease in blood and brain tissue.
.
Transl Psychiatry. 11(1):250.
PubMed
Pathak GA
,
Zhou Z
,
Silzer TK
,
Barber RC
,
Phillips NR
. 2020.
Two-stage Bayesian GWAS of 9576 individuals identifies SNP regions that are targeted by miRNAs inversely expressed in Alzheimer's and cancer.
.
Alzheimers Dement. 16(1):162-177.
PubMed
Patrick E
,
Olah M
,
Taga M
,
Klein H-U
,
Xu J
,
White CC
,
Felsky D
,
Agrawal S
,
Gaiteri C
,
Chibnik LB
et al.
. 2021.
A cortical immune network map identifies distinct microglial transcriptional programs associated with β-amyloid and Tau pathologies.
.
Transl Psychiatry. 11(1):50.
PubMed
Peloso GM
,
Beiser AS
,
Satizabal CL
,
Xanthakis V
,
Vasan RS
,
Pase MP
,
DeStefano AL
,
Seshadri S
. 2020.
Cardiovascular health, genetic risk, and risk of dementia in the Framingham Heart Study.
.
Neurology. 95(10):e1341-e1350.
PubMed
Peloso GM
,
Beiser AS
,
DeStefano AL
,
Seshadri S
. 2018.
Genetic Interaction with Plasma Lipids on Alzheimer's Disease in the Framingham Heart Study.
.
J Alzheimers Dis. 66(3):1275-1282.
PubMed
Peng B
,
Yao X
,
Risacher SL
,
Saykin AJ
,
Shen L
,
Ning X
. 2020.
Cognitive biomarker prioritization in Alzheimer's Disease using brain morphometric data.
.
BMC Med Inform Decis Mak. 20(1):319.
PubMed
Pillai JA
,
Bebek G
,
Khrestian M
,
Bena J
,
Bergmann CC
,
Bush WS
,
Leverenz JB
,
Bekris LM
. 2021.
Gene Variants and Related Soluble TNFR2 Levels Impact Resilience in Alzheimer's Disease.
.
Front Aging Neurosci. 13:638922.
PubMed
Podleśny-Drabiniok A
,
Marcora E
,
Goate AM
. 2020.
Microglial Phagocytosis: A Disease-Associated Process Emerging from Alzheimer's Disease Genetics.
.
Trends Neurosci. 43(12):965-979.
PubMed
R
Raghavan NS
,
Dumitrescu L
,
Mormino E
,
Mahoney ER
,
Lee AJ
,
Gao Y
,
Bilgel M
,
Goldstein D
,
Harrison T
,
Engelman CD
et al.
. 2020.
Association Between Common Variants in RBFOX1, an RNA-Binding Protein, and Brain Amyloidosis in Early and Preclinical Alzheimer Disease.
.
JAMA Neurol. 77(10):1288-1298.
PubMed
Raghavan NS
,
Brickman AM
,
Andrews H
,
Manly JJ
,
Schupf N
,
Lantigua R
,
Wolock CJ
,
Kamalakaran S
,
Petrovski S
,
Tosto G
et al.
. 2018.
Whole-exome sequencing in 20,197 persons for rare variants in Alzheimer's disease.
.
Ann Clin Transl Neurol. 5(7):832-842.
PubMed
Rajabli F
,
Feliciano-Astacio BE
,
Cukier HN
,
Wang L
,
Griswold AJ
,
Hamilton-Nelson KL
,
Adams LD
,
Rodriguez VC
,
Mena PR
,
Tejada S
et al.
. 2021.
Linkage of Alzheimer disease families with Puerto Rican ancestry identifies a chromosome 9 locus.
.
Neurobiol Aging. 104:115.e1-115.e7.
PubMed
Rajabli F
,
Feliciano BE
,
Celis K
,
Hamilton-Nelson KL
,
Whitehead PL
,
Adams LD
,
Bussies PL
,
Manrique CP
,
Rodriguez A
,
Rodriguez V
et al.
. 2018.
Ancestral origin of ApoE ε4 Alzheimer disease risk in Puerto Rican and African American populations.
.
PLoS Genet. 14(12):e1007791.
PubMed
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