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Title
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Type
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Year
Journal Article
Lananna BV
,
McKee CA
,
King MW
,
Del-Aguila JL
,
Dimitry JM
,
Farias FHG
,
Nadarajah CJ
,
Xiong DD
,
Guo C
,
Cammack AJ
et al.
. 2020.
/YKL-40 is controlled by the astrocyte circadian clock and regulates neuroinflammation and Alzheimer's disease pathogenesis.
.
Sci Transl Med. 12(574)
PubMed
Raghavan NS
,
Brickman AM
,
Andrews H
,
Manly JJ
,
Schupf N
,
Lantigua R
,
Wolock CJ
,
Kamalakaran S
,
Petrovski S
,
Tosto G
et al.
. 2018.
Whole-exome sequencing in 20,197 persons for rare variants in Alzheimer's disease.
.
Ann Clin Transl Neurol. 5(7):832-842.
PubMed
Vardarajan BN
,
Barral S
,
Jaworski J
,
Beecham GW
,
Blue E
,
Tosto G
,
Reyes-Dumeyer D
,
Medrano M
,
Lantigua R
,
Naj A
et al.
. 2018.
Whole genome sequencing of Caribbean Hispanic families with late-onset Alzheimer's disease.
.
Ann Clin Transl Neurol. 5(4):406-417.
PubMed
Bis JC
,
Jian X
,
Kunkle BW
,
Chen Y
,
Hamilton-Nelson KL
,
Bush WS
,
Salerno WJ
,
Lancour D
,
Ma Y
,
Renton AE
et al.
. 2018.
Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation.
.
Mol Psychiatry.
PubMed
Lin H
,
Satizabal C
,
Xie Z
,
Yang Q
,
Huan T
,
Joehanes R
,
Wen C
,
Munson PJ
,
Beiser A
,
Levy D
et al.
. 2017.
Whole blood gene expression and white matter Hyperintensities.
.
Mol Neurodegener. 12(1):67.
PubMed
Leung YYee
,
Valladares O
,
Chou Y-F
,
Lin H-J
,
Kuzma AB
,
Cantwell L
,
Qu L
,
Gangadharan P
,
Salerno WJ
,
Schellenberg GD
et al.
. 2018.
VCPA: genomic Variant Calling pipeline and data management tool for Alzheimer's Disease Sequencing Project.
.
Bioinformatics.
PubMed
Adams S
,
Conner S
,
Himali JJ
,
Beiser A
,
Vasan RS
,
Seshadri S
,
Pase MP
. 2018.
Vascular risk factor burden and new-onset depression in the community.
.
Prev Med. 111:348-350.
PubMed
Blue EE
,
Yu C-E
,
Thornton TA
,
Chapman NH
,
Kernfeld E
,
Jiang N
,
Shively KM
,
Buckingham KJ
,
Marvin CT
,
Bamshad MJ
et al.
. 2018.
Variants regulating ZBTB4 are associated with age-at-onset of Alzheimer's disease.
.
Genes Brain Behav. 17(6):e12429.
PubMed
Lyon MS
,
Andrews SJ
,
Elsworth B
,
Gaunt TR
,
Hemani G
,
Marcora E
. 2021.
The variant call format provides efficient and robust storage of GWAS summary statistics.
.
Genome Biol. 22(1):32.
PubMed
Mock C
,
Teylan M
,
Beecham G
,
Besser L
,
Cairns NJ
,
Crary JF
,
Katsumata Y
,
Nelson PT
,
Kukull W
. 2020.
The Utility of the National Alzheimer's Coordinating Center's Database for the Rapid Assessment of Evolving Neuropathologic Conditions.
.
Alzheimer Dis Assoc Disord. 34(2):105-111.
PubMed
Amlie-Wolf A
,
Kuksa PP
,
Lee C-Y
,
Mlynarski E
,
Leung YYee
,
San Wang L-
. 2021.
Using INFERNO to Infer the Molecular Mechanisms Underlying Noncoding Genetic Associations.
.
Methods Mol Biol. 2254:73-91.
PubMed
Bussies PL
,
Rajabli F
,
Griswold A
,
Dorfsman DA
,
Whitehead P
,
Adams LD
,
Mena PR
,
Cuccaro M
,
Haines JL
,
Byrd GS
et al.
. 2020.
Use of local genetic ancestry to assess -523' and risk for Alzheimer disease.
.
Neurol Genet. 6(2):e404.
PubMed
Kowalski MH
,
Qian H
,
Hou Z
,
Rosen JD
,
Tapia AL
,
Shan Y
,
Jain D
,
Argos M
,
Arnett DK
,
Avery C
et al.
. 2019.
Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations.
.
PLoS Genet. 15(12):e1008500.
PubMed
Pathak GA
,
Zhou Z
,
Silzer TK
,
Barber RC
,
Phillips NR
. 2020.
Two-stage Bayesian GWAS of 9576 individuals identifies SNP regions that are targeted by miRNAs inversely expressed in Alzheimer's and cancer.
.
Alzheimers Dement. 16(1):162-177.
PubMed
Cignarella F
,
Filipello F
,
Bollman B
,
Cantoni C
,
Locca A
,
Mikesell R
,
Manis M
,
Ibrahim A
,
Deng L
,
Benitez BA
et al.
. 2020.
TREM2 activation on microglia promotes myelin debris clearance and remyelination in a model of multiple sclerosis.
.
Acta Neuropathol. 140(4):513-534.
PubMed
He Z
,
McBride JD
,
Xu H
,
Changolkar L
,
Kim S-J
,
Zhang B
,
Narasimhan S
,
Gibbons GS
,
Guo JL
,
Kozak M
et al.
. 2020.
Transmission of tauopathy strains is independent of their isoform composition.
.
Nat Commun. 11(1):7.
PubMed
Katsumata Y
,
Nelson PT
,
Estus S
,
Fardo DW
. 2019.
Translating Alzheimer's disease-associated polymorphisms into functional candidates: a survey of IGAP genes and SNPs.
.
Neurobiol Aging. 74:135-146.
PubMed
Wang M
,
Li A
,
Sekiya M
,
Beckmann ND
,
Quan X
,
Schrode N
,
Fernando MB
,
Yu A
,
Zhu L
,
Cao J
et al.
. 2021.
Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer's Disease.
.
Neuron. 109(2):257-272.e14.
PubMed
Li Z
,
Farias FHG
,
Dube U
,
Del-Aguila JL
,
Mihindukulasuriya KA
,
Fernández MVictoria
,
Ibañez L
,
Budde JP
,
Wang F
,
Lake AM
et al.
. 2020.
The TMEM106B FTLD-protective variant, rs1990621, is also associated with increased neuronal proportion.
.
Acta Neuropathol. 139(1):45-61.
PubMed
Goldschmidt-Clermont PJ
,
Volinsky FG
,
LaRosa SP
,
Gilbert JR
,
Pericak-Vance MA
. 2020.
Time for Well-Powered Controlled Prospective Studies to Test a Causal Role for Herpes Viruses in Alzheimer's Disease Using Antiherpetic Drugs.
.
J Gerontol A Biol Sci Med Sci. 75(6):1058-1060.
PubMed
Ramdhani S
,
Navarro E
,
Udine E
,
Efthymiou AG
,
Schilder BM
,
Parks M
,
Goate A
,
Raj T
. 2020.
Tensor decomposition of stimulated monocyte and macrophage gene expression profiles identifies neurodegenerative disease-specific trans-eQTLs.
.
PLoS Genet. 16(2):e1008549.
PubMed
Hsu S
,
Pimenova AA
,
Hayes K
,
Villa JA
,
Rosene MJ
,
Jere M
,
Goate AM
,
Karch CM
. 2020.
Systematic validation of variants of unknown significance in APP, PSEN1 and PSEN2.
.
Neurobiol Dis. 139:104817.
PubMed
Wang S
,
Lindroth H
,
Chan C
,
Greene R
,
Serrano-Andrews P
,
Khan S
,
Rios G
,
Jabbari S
,
Lim J
,
Saykin AJ
et al.
. 2021.
A Systematic Review of Delirium Biomarkers and Their Alignment with the NIA-AA Research Framework.
.
J Am Geriatr Soc. 69(1):255-263.
PubMed
Ebbert MTW
,
Jensen TD
,
Jansen-West K
,
Sens JP
,
Reddy JS
,
Ridge PG
,
Kauwe JSK
,
Belzil V
,
Pregent L
,
Carrasquillo MM
et al.
. 2019.
Systematic analysis of dark and camouflaged genes reveals disease-relevant genes hiding in plain sight.
.
Genome Biol. 20(1):97.
PubMed
Tang M
,
Alaniz MEugenia
,
Felsky D
,
Vardarajan B
,
Reyes-Dumeyer D
,
Lantigua R
,
Medrano M
,
Bennett DA
,
De Jager PL
,
Mayeux R
et al.
. 2020.
Synonymous variants associated with Alzheimer disease in multiplex families.
.
Neurol Genet. 6(4):e450.
PubMed
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