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A
Fernández MVictoria
,
Kim JHun
,
Budde JP
,
Black K
,
Medvedeva A
,
Saef B
,
Deming Y
,
Del-Aguila J
,
Ibañez L
,
Dube U
et al.
. 2017.
Analysis of neurodegenerative Mendelian genes in clinically diagnosed Alzheimer Disease.
.
PLoS Genet. 13(11):e1007045.
PubMed
Granot-Hershkovitz E
,
Tarraf W
,
Kurniansyah N
,
Daviglus M
,
Isasi CR
,
Kaplan R
,
Lamar M
,
Perreira KM
,
Wassertheil-Smoller S
,
Stickel A
et al.
. 2021.
APOE alleles' association with cognitive function differs across Hispanic/Latino groups and genetic ancestry in the study of Latinos-investigation of neurocognitive aging (HCHS/SOL).
.
Alzheimers Dement. 17(3):466-474.
PubMed
Raghavan NS
,
Dumitrescu L
,
Mormino E
,
Mahoney ER
,
Lee AJ
,
Gao Y
,
Bilgel M
,
Goldstein D
,
Harrison T
,
Engelman CD
et al.
. 2020.
Association Between Common Variants in RBFOX1, an RNA-Binding Protein, and Brain Amyloidosis in Early and Preclinical Alzheimer Disease.
.
JAMA Neurol. 77(10):1288-1298.
PubMed
Tynkkynen J
,
Chouraki V
,
van der Lee SJ
,
Hernesniemi J
,
Yang Q
,
Li S
,
Beiser A
,
Larson MG
,
Sääksjärvi K
,
Shipley MJ
et al.
. 2018.
Association of branched-chain amino acids and other circulating metabolites with risk of incident dementia and Alzheimer's disease: A prospective study in eight cohorts.
.
Alzheimers Dement. 14(6):723-733.
PubMed
van der Meer D
,
Sønderby IE
,
Kaufmann T
,
G Walters B
,
Abdellaoui A
,
Ames D
,
Amunts K
,
Andersson M
,
Armstrong NJ
,
Bernard M
et al.
. 2020.
Association of Copy Number Variation of the 15q11.2 BP1-BP2 Region With Cortical and Subcortical Morphology and Cognition.
.
JAMA Psychiatry. 77(4):420-430.
PubMed
Belloy ME
,
Napolioni V
,
Han SS
,
Le Guen Y
,
Greicius MD
. 2020.
Association of Klotho-VS Heterozygosity With Risk of Alzheimer Disease in Individuals Who Carry APOE4.
.
JAMA Neurol. 77(7):849-862.
PubMed
Mishra A
,
Chauhan G
,
Violleau M-H
,
Vojinovic D
,
Jian X
,
Bis JC
,
Li S
,
Saba Y
,
Grenier-Boley B
,
Yang Q
et al.
. 2019.
Association of variants in HTRA1 and NOTCH3 with MRI-defined extremes of cerebral small vessel disease in older subjects.
.
Brain. 142(4):1009-1023.
PubMed
Walker JM
,
Fudym Y
,
Farrell K
,
Iida MA
,
Bieniek KF
,
Seshadri S
,
White CL
,
Crary JF
,
Richardson TE
. 2021.
Asymmetry of Hippocampal Tau Pathology in Primary Age-Related Tauopathy and Alzheimer Disease.
.
J Neuropathol Exp Neurol. 80(5):436-445.
PubMed
Weinstein G
,
Davis-Plourde K
,
Beiser AS
,
Seshadri S
. 2021.
Autonomic Imbalance and Risk of Dementia and Stroke: The Framingham Study.
.
Stroke. 52(6):2068-2076.
PubMed
C
Peloso GM
,
Beiser AS
,
Satizabal CL
,
Xanthakis V
,
Vasan RS
,
Pase MP
,
DeStefano AL
,
Seshadri S
. 2020.
Cardiovascular health, genetic risk, and risk of dementia in the Framingham Heart Study.
.
Neurology. 95(10):e1341-e1350.
PubMed
Andrews SJ
,
Fulton-Howard B
,
O'Reilly P
,
Marcora E
,
Goate AM
. 2021.
Causal Associations Between Modifiable Risk Factors and the Alzheimer's Phenome.
.
Ann Neurol. 89(1):54-65.
PubMed
Raman MR
,
Himali JJ
,
Conner SC
,
DeCarli C
,
Vasan RS
,
Beiser AS
,
Seshadri S
,
Maillard P
,
Satizabal CL
. 2018.
Circulating Vascular Growth Factors and Magnetic Resonance Imaging Markers of Small Vessel Disease and Atrophy in Middle-Aged Adults.
.
Stroke. 49(9):2227-2229.
PubMed
Wang L
,
Qiao Y
,
Zhang H
,
Zhang Y
,
Hua J
,
Jin S
,
Liu G
. 2020.
Circulating Vitamin D Levels and Alzheimer's Disease: A Mendelian Randomization Study in the IGAP and UK Biobank.
.
J Alzheimers Dis. 73(2):609-618.
PubMed
Armstrong NJ
,
Mather KA
,
Sargurupremraj M
,
Knol MJ
,
Malik R
,
Satizabal CL
,
Yanek LR
,
Wen W
,
Gudnason VG
,
Dueker ND
et al.
. 2020.
Common Genetic Variation Indicates Separate Causes for Periventricular and Deep White Matter Hyperintensities.
.
Stroke. 51(7):2111-2121.
PubMed
de Rojas I
,
Moreno-Grau S
,
Tesi N
,
Grenier-Boley B
,
Andrade V
,
Jansen IE
,
Pedersen NL
,
Stringa N
,
Zettergren A
,
Hernández I
et al.
. 2021.
Common variants in Alzheimer's disease and risk stratification by polygenic risk scores.
.
Nat Commun. 12(1):3417.
PubMed
Ouellette AR
,
Neuner SM
,
Dumitrescu L
,
Anderson LC
,
Gatti DM
,
Mahoney ER
,
Bubier JA
,
Churchill G
,
Peters L
,
Huentelman MJ
et al.
. 2020.
Cross-Species Analyses Identify Dlgap2 as a Regulator of Age-Related Cognitive Decline and Alzheimer's Dementia.
.
Cell Rep. 32(9):108091.
PubMed
D
Lee J
,
Khobragade PY
,
Banerjee J
,
Chien S
,
Angrisani M
,
Perianayagam A
,
Bloom DE
,
Dey AB
. 2020.
Design and Methodology of the Longitudinal Aging Study in India-Diagnostic Assessment of Dementia (LASI-DAD).
.
J Am Geriatr Soc. 68 Suppl 3:S5-S10.
PubMed
E
Reiman EM
,
Arboleda-Velasquez JF
,
Quiroz YT
,
Huentelman MJ
,
Beach TG
,
Caselli RJ
,
Chen Y
,
Su Y
,
Myers AJ
,
Hardy J
et al.
. 2020.
Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study.
.
Nat Commun. 11(1):667.
PubMed
F
Ibañez L
,
Bahena JA
,
Yang C
,
Dube U
,
Farias FHG
,
Budde JP
,
Bergmann K
,
Brenner-Webster C
,
Morris JC
,
Perrin RJ
et al.
. 2020.
Functional genomic analyses uncover APOE-mediated regulation of brain and cerebrospinal fluid beta-amyloid levels in Parkinson disease.
.
Acta Neuropathol Commun. 8(1):196.
PubMed
G
Satizabal CL
,
Adams HHH
,
Hibar DP
,
White CC
,
Knol MJ
,
Stein JL
,
Scholz M
,
Sargurupremraj M
,
Jahanshad N
,
Roshchupkin GV
et al.
. 2019.
Genetic architecture of subcortical brain structures in 38,851 individuals.
.
Nat Genet. 51(11):1624-1636.
PubMed
Hofer E
,
Roshchupkin GV
,
Adams HHH
,
Knol MJ
,
Lin H
,
Li S
,
Zare H
,
Ahmad S
,
Armstrong NJ
,
Satizabal CL
et al.
. 2020.
Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults.
.
Nat Commun. 11(1):4796.
PubMed
Peloso GM
,
Beiser AS
,
DeStefano AL
,
Seshadri S
. 2018.
Genetic Interaction with Plasma Lipids on Alzheimer's Disease in the Framingham Heart Study.
.
J Alzheimers Dis. 66(3):1275-1282.
PubMed
de Vries PS
,
Sabater-Lleal M
,
Huffman JE
,
Marten J
,
Song C
,
Pankratz N
,
Bartz TM
,
de Haan HG
,
Delgado GE
,
Eicher JD
et al.
. 2019.
A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology.
.
Blood. 133(9):967-977.
PubMed
Huan T
,
Joehanes R
,
Song C
,
Peng F
,
Guo Y
,
Mendelson M
,
Yao C
,
Liu C
,
Ma J
,
Richard M
et al.
. 2019.
Genome-wide identification of DNA methylation QTLs in whole blood highlights pathways for cardiovascular disease.
.
Nat Commun. 10(1):4267.
PubMed
Kunkle BW
,
Jaworski J
,
Barral S
,
Vardarajan B
,
Beecham GW
,
Martin ER
,
Cantwell LS
,
Partch A
,
Bird TD
,
Raskind WH
et al.
. 2016.
Genome-wide linkage analyses of non-Hispanic white families identify novel loci for familial late-onset Alzheimer's disease.
.
Alzheimers Dement. 12(1):2-10.
PubMed
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