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2021
He Z
,
Liu L
,
Wang C
,
Le Guen Y
,
Lee J
,
Gogarten S
,
Lu F
,
Montgomery S
,
Tang H
,
Silverman EK
et al.
. 2021.
Identification of putative causal loci in whole-genome sequencing data via knockoff statistics.
.
Nat Commun. 12(1):3152.
PubMed
Baird DA
,
Liu JZ
,
Zheng J
,
Sieberts SK
,
Perumal T
,
Elsworth B
,
Richardson TG
,
Chen C-Y
,
Carrasquillo MM
,
Allen M
et al.
. 2021.
Identifying drug targets for neurological and psychiatric disease via genetics and the brain transcriptome.
.
PLoS Genet. 17(1):e1009224.
PubMed
Xu H
,
O'Reilly M
,
Gibbons GS
,
Changolkar L
,
McBride JD
,
Riddle DM
,
Zhang B
,
Stieber A
,
Nirschl J
,
Kim S-J
et al.
. 2021.
In vitro amplification of pathogenic tau conserves disease-specific bioactive characteristics.
.
Acta Neuropathol. 141(2):193-215.
PubMed
Griswold AJ
,
Celis K
,
Bussies PL
,
Rajabli F
,
Whitehead PL
,
Hamilton-Nelson KL
,
Beecham GW
,
Dykxhoorn DM
,
Nuytemans K
,
Wang L
et al.
. 2021.
Increased APOE ε4 expression is associated with the difference in Alzheimer's disease risk from diverse ancestral backgrounds.
.
Alzheimers Dement. 17(7):1179-1188.
PubMed
Wingo AP
,
Liu Y
,
Gerasimov ES
,
Gockley J
,
Logsdon BA
,
Duong DM
,
Dammer EB
,
Robins C
,
Beach TG
,
Reiman EM
et al.
. 2021.
Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer's disease pathogenesis.
.
Nat Genet. 53(2):143-146.
PubMed
Novikova G
,
Kapoor M
,
Tcw J
,
Abud EM
,
Efthymiou AG
,
Chen SX
,
Cheng H
,
Fullard JF
,
Bendl J
,
Liu Y
et al.
. 2021.
Integration of Alzheimer's disease genetics and myeloid genomics identifies disease risk regulatory elements and genes.
.
Nat Commun. 12(1):1610.
PubMed
Panitch R
,
Hu J
,
Chung J
,
Zhu C
,
Meng G
,
Xia W
,
Bennett DA
,
Lunetta KL
,
Ikezu T
,
Au R
et al.
. 2021.
Integrative brain transcriptome analysis links complement component 4 and HSPA2 to the APOE ε2 protective effect in Alzheimer disease.
.
Mol Psychiatry. 26(10):6054-6064.
PubMed
2020
Griswold AJ
,
Sivasankaran SK
,
Van Booven D
,
Gardner OK
,
Rajabli F
,
Whitehead PL
,
Hamilton-Nelson KL
,
Adams LD
,
Scott AM
,
Hofmann NK
et al.
. 2020.
Immune and Inflammatory Pathways Implicated by Whole Blood Transcriptomic Analysis in a Diverse Ancestry Alzheimer's Disease Cohort.
.
J Alzheimers Dis. 76(3):1047-1060.
PubMed
Ayata P
,
Schaefer A
. 2020.
Innate sensing of mechanical properties of brain tissue by microglia.
.
Curr Opin Immunol. 62:123-130.
PubMed
Weitzman SA
,
Narasimhan S
,
He Z
,
Changolkar L
,
McBride JD
,
Zhang B
,
Schellenberg GD
,
Trojanowski JQ
,
M Y Lee V
. 2020.
Insoluble Tau From Human FTDP-17 Cases Exhibit Unique Transmission Properties In Vivo.
.
J Neuropathol Exp Neurol. 79(9):941-949.
PubMed
Devanand DP
,
Lee S
,
Luchsinger JA
,
Andrews H
,
Goldberg T
,
Huey ED
,
Schupf N
,
Manly J
,
Stern Y
,
Kreisl WC
et al.
. 2020.
Intact global cognitive and olfactory ability predicts lack of transition to dementia.
.
Alzheimers Dement. 16(2):326-334.
PubMed
Ajnakina O
,
Cadar D
,
Steptoe A
. 2020.
Interplay between Socioeconomic Markers and Polygenic Predisposition on Timing of Dementia Diagnosis.
.
J Am Geriatr Soc. 68(7):1529-1536.
PubMed
Andrews SJ
,
Fulton-Howard B
,
Goate A
. 2020.
Interpretation of risk loci from genome-wide association studies of Alzheimer's disease.
.
Lancet Neurol. 19(4):326-335.
PubMed
Lee J
,
Dey AB
. 2020.
Introduction to LASI-DAD: The Longitudinal Aging Study in India-Diagnostic Assessment of Dementia.
.
J Am Geriatr Soc. 68 Suppl 3:S3-S4.
PubMed
2019
Lo M-T
,
Kauppi K
,
Fan C-C
,
Sanyal N
,
Reas ET
,
Sundar VS
,
Lee W-C
,
Desikan RS
,
McEvoy LK
,
Chen C-H
. 2019.
Identification of genetic heterogeneity of Alzheimer's disease across age.
.
Neurobiol Aging. 84:243.e1-243.e9.
PubMed
Wolters FJ
,
Yang Q
,
Biggs ML
,
Jakobsdottir J
,
Li S
,
Evans DS
,
Bis JC
,
Harris TB
,
Vasan RS
,
Zilhao NR
et al.
. 2019.
The impact of APOE genotype on survival: Results of 38,537 participants from six population-based cohorts (E2-CHARGE).
.
PLoS One. 14(7):e0219668.
PubMed
Vasan RS
,
Short MI
,
Niiranen TJ
,
Xanthakis V
,
DeCarli C
,
Cheng S
,
Seshadri S
,
Mitchell GF
. 2019.
Interrelations Between Arterial Stiffness, Target Organ Damage, and Cardiovascular Disease Outcomes.
.
J Am Heart Assoc. 8(14):e012141.
PubMed
2018
Amlie-Wolf A
,
Tang M
,
Mlynarski EE
,
Kuksa PP
,
Valladares O
,
Katanić Ž
,
Tsuang D
,
Brown CD
,
Schellenberg GD
,
San Wang L-
. 2018.
INFERNO: inferring the molecular mechanisms of noncoding genetic variants.
.
Nucleic Acids Res. 46(17):8740-8753.
PubMed
Zhou Z
,
Wang W
,
San Wang L-
,
Zhang NRuonan
. 2018.
Integrative DNA copy number detection and genotyping from sequencing and array-based platforms.
.
Bioinformatics. 34(14):2349-2355.
PubMed
Jiang S
,
Wen N
,
Li Z
,
Dube U
,
Del Aguila J
,
Budde J
,
Martinez R
,
Hsu S
,
Fernández MV
,
Cairns NJ
et al.
. 2018.
Integrative system biology analyses of CRISPR-edited iPSC-derived neurons and human brains reveal deficiencies of presynaptic signaling in FTLD and PSP.
.
Transl Psychiatry. 8(1):265.
PubMed
2017
Butkiewicz M
,
Haines JL
,
Bush WS
. 2017.
Introducing COCOS: codon consequence scanner for annotating reading frame changes induced by stop-lost and frame shift variants.
.
Bioinformatics. 33(10):1561-1562.
PubMed
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