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2021
Wang H, Bennett DA, De Jager PL, Zhang Q-Y, Zhang H-Y.  2021.  Genome-wide epistasis analysis for Alzheimer's disease and implications for genetic risk prediction.. Alzheimers Res Ther. 13(1):55.
Fulton-Howard B, Goate AM, Adelson RP, Koppel J, Gordon ML, Barzilai N, Atzmon G, Davies P, Freudenberg-Hua Y.  2021.  Greater effect of polygenic risk score for Alzheimer's disease among younger cases who are apolipoprotein E-ε4 carriers.. Neurobiol Aging. 99:101.e1-101.e9.
Wu HMan, Goate AM, O'Reilly PF.  2021.  Heterogeneous effects of genetic risk for Alzheimer's disease on the phenome.. Transl Psychiatry. 11(1):406.
He Z, Liu L, Wang C, Le Guen Y, Lee J, Gogarten S, Lu F, Montgomery S, Tang H, Silverman EK et al..  2021.  Identification of putative causal loci in whole-genome sequencing data via knockoff statistics.. Nat Commun. 12(1):3152.
Baird DA, Liu JZ, Zheng J, Sieberts SK, Perumal T, Elsworth B, Richardson TG, Chen C-Y, Carrasquillo MM, Allen M et al..  2021.  Identifying drug targets for neurological and psychiatric disease via genetics and the brain transcriptome.. PLoS Genet. 17(1):e1009224.
Xu H, O'Reilly M, Gibbons GS, Changolkar L, McBride JD, Riddle DM, Zhang B, Stieber A, Nirschl J, Kim S-J et al..  2021.  In vitro amplification of pathogenic tau conserves disease-specific bioactive characteristics.. Acta Neuropathol. 141(2):193-215.
Griswold AJ, Celis K, Bussies PL, Rajabli F, Whitehead PL, Hamilton-Nelson KL, Beecham GW, Dykxhoorn DM, Nuytemans K, Wang L et al..  2021.  Increased APOE ε4 expression is associated with the difference in Alzheimer's disease risk from diverse ancestral backgrounds.. Alzheimers Dement. 17(7):1179-1188.
Wingo AP, Liu Y, Gerasimov ES, Gockley J, Logsdon BA, Duong DM, Dammer EB, Robins C, Beach TG, Reiman EM et al..  2021.  Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer's disease pathogenesis.. Nat Genet. 53(2):143-146.
Novikova G, Kapoor M, Tcw J, Abud EM, Efthymiou AG, Chen SX, Cheng H, Fullard JF, Bendl J, Liu Y et al..  2021.  Integration of Alzheimer's disease genetics and myeloid genomics identifies disease risk regulatory elements and genes.. Nat Commun. 12(1):1610.
Panitch R, Hu J, Chung J, Zhu C, Meng G, Xia W, Bennett DA, Lunetta KL, Ikezu T, Au R et al..  2021.  Integrative brain transcriptome analysis links complement component 4 and HSPA2 to the APOE ε2 protective effect in Alzheimer disease.. Mol Psychiatry. 26(10):6054-6064.
Kirola L, Budde JP, Wang F, Norton J, Morris JC, Cruchaga C, Fernández MVictoria.  2021.  Lack of evidence supporting a role for DPP6 sequence variants in Alzheimer's disease in the European American population.. Acta Neuropathol. 141(4):623-624.
Lyons CE, Zhou X, Razzoli M, Chen M, Xia W, Ashe K, Zhang B, Bartolomucci A.  2021.  Lifelong chronic psychosocial stress induces a proteomic signature of Alzheimer's disease in wildtype mice.. Eur J Neurosci.
Rajabli F, Feliciano-Astacio BE, Cukier HN, Wang L, Griswold AJ, Hamilton-Nelson KL, Adams LD, Rodriguez VC, Mena PR, Tejada S et al..  2021.  Linkage of Alzheimer disease families with Puerto Rican ancestry identifies a chromosome 9 locus.. Neurobiol Aging. 104:115.e1-115.e7.
Moreno-Grau S, Fernández MVictoria, de Rojas I, García-González P, Hernández I, Farias F, Budde JP, Quintela I, Madrid L, González-Perez A et al..  2021.  Long runs of homozygosity are associated with Alzheimer's disease.. Transl Psychiatry. 11(1):142.
Ramos J, Chowdhury AR, Caywood LJ, Prough M, M Fuzzell D, Fuzzell S, Miskimen K, Whitehead PL, Adams LD, Laux R et al..  2021.  Lower Levels of Education Are Associated with Cognitive Impairment in the Old Order Amish.. J Alzheimers Dis. 79(1):451-458.
Rentería MArce, Manly JJ, Vonk JMJ, Arango SMejia, Obregon AMichaels, Samper-Ternent R, Wong R, Barral S, Tosto G.  2021.  Midlife Vascular Factors and Prevalence of Mild Cognitive Impairment in Late-Life in Mexico.. J Int Neuropsychol Soc. :1-11.
Malik R, Georgakis MK, Neitzel J, Rannikmäe K, Ewers M, Seshadri S, Sudlow CLM, Dichgans M.  2021.  Midlife vascular risk factors and risk of incident dementia: Longitudinal cohort and Mendelian randomization analyses in the UK Biobank.. Alzheimers Dement. 17(9):1422-1431.
Neff RA, Wang M, Vatansever S, Guo L, Ming C, Wang Q, Wang E, Horgusluoglu-Moloch E, Song W-M, Li A et al..  2021.  Molecular subtyping of Alzheimer's disease using RNA sequencing data reveals novel mechanisms and targets.. Sci Adv. 7(2)
Madrid L, Moreno-Grau S, Ahmad S, González-Perez A, de Rojas I, Xia R, Adami PVMartino, García-González P, Kleineidam L, Yang Q et al..  2021.  Multiomics integrative analysis identifies allele-specific blood biomarkers associated to Alzheimer's disease etiopathogenesis.. Aging (Albany NY). 13(7):9277-9329.
Blue EE, Thornton TA, Kooperberg C, Liu S, Wactawski-Wende J, Manson JA, Kuller L, Hayden K, Reiner AP.  2021.  Non-coding variants in MYH11, FZD3, and SORCS3 are associated with dementia in women.. Alzheimers Dement. 17(2):215-225.
Kunkle BW, Schmidt M, Klein H-U, Naj AC, Hamilton-Nelson KL, Larson EB, Evans DA, De Jager PL, Crane PK, Buxbaum JD et al..  2021.  Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis.. JAMA Neurol. 78(1):102-113.
Dewan R, Chia R, Ding J, Hickman RA, Stein TD, Abramzon Y, Ahmed S, Sabir MS, Portley MK, Tucci A et al..  2021.  Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis.. Neuron. 109(3):448-460.e4.
Damotte V, van der Lee SJ, Chouraki V, Grenier-Boley B, Simino J, Adams H, Tosto G, White C, Terzikhan N, Cruchaga C et al..  2021.  Plasma amyloid β levels are driven by genetic variants near APOE, BACE1, APP, PSEN2: A genome-wide association study in over 12,000 non-demented participants.. Alzheimers Dement. 17(10):1663-1674.
Brickman AM, Manly JJ, Honig LS, Sanchez D, Reyes-Dumeyer D, Lantigua RA, Lao PJ, Stern Y, Vonsattel JPaul, Teich AF et al..  2021.  Plasma p-tau181, p-tau217, and other blood-based Alzheimer's disease biomarkers in a multi-ethnic, community study.. Alzheimers Dement. 17(8):1353-1364.
Sariya S, Felsky D, Reyes-Dumeyer D, Lali R, Lantigua RA, Vardarajan B, Jimenez-Velazquez IZ, Haines JL, Shellenberg GD, Pericak-Vance MA et al..  2021.  Polygenic Risk Score for Alzheimer's Disease in Caribbean Hispanics.. Ann Neurol. 90(3):366-376.

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