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Author
Title
[
Type
]
Year
Journal Article
Jiang S
,
Wen N
,
Li Z
,
Dube U
,
Del Aguila J
,
Budde J
,
Martinez R
,
Hsu S
,
Fernández MV
,
Cairns NJ
et al.
. 2018.
Integrative system biology analyses of CRISPR-edited iPSC-derived neurons and human brains reveal deficiencies of presynaptic signaling in FTLD and PSP.
.
Transl Psychiatry. 8(1):265.
PubMed
Zhou Z
,
Wang W
,
San Wang L-
,
Zhang NRuonan
. 2018.
Integrative DNA copy number detection and genotyping from sequencing and array-based platforms.
.
Bioinformatics. 34(14):2349-2355.
PubMed
Panitch R
,
Hu J
,
Chung J
,
Zhu C
,
Meng G
,
Xia W
,
Bennett DA
,
Lunetta KL
,
Ikezu T
,
Au R
et al.
. 2021.
Integrative brain transcriptome analysis links complement component 4 and HSPA2 to the APOE ε2 protective effect in Alzheimer disease.
.
Mol Psychiatry. 26(10):6054-6064.
PubMed
Novikova G
,
Kapoor M
,
Tcw J
,
Abud EM
,
Efthymiou AG
,
Chen SX
,
Cheng H
,
Fullard JF
,
Bendl J
,
Liu Y
et al.
. 2021.
Integration of Alzheimer's disease genetics and myeloid genomics identifies disease risk regulatory elements and genes.
.
Nat Commun. 12(1):1610.
PubMed
Wingo AP
,
Liu Y
,
Gerasimov ES
,
Gockley J
,
Logsdon BA
,
Duong DM
,
Dammer EB
,
Robins C
,
Beach TG
,
Reiman EM
et al.
. 2021.
Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer's disease pathogenesis.
.
Nat Genet. 53(2):143-146.
PubMed
Devanand DP
,
Lee S
,
Luchsinger JA
,
Andrews H
,
Goldberg T
,
Huey ED
,
Schupf N
,
Manly J
,
Stern Y
,
Kreisl WC
et al.
. 2020.
Intact global cognitive and olfactory ability predicts lack of transition to dementia.
.
Alzheimers Dement. 16(2):326-334.
PubMed
Weitzman SA
,
Narasimhan S
,
He Z
,
Changolkar L
,
McBride JD
,
Zhang B
,
Schellenberg GD
,
Trojanowski JQ
,
M Y Lee V
. 2020.
Insoluble Tau From Human FTDP-17 Cases Exhibit Unique Transmission Properties In Vivo.
.
J Neuropathol Exp Neurol. 79(9):941-949.
PubMed
Ayata P
,
Schaefer A
. 2020.
Innate sensing of mechanical properties of brain tissue by microglia.
.
Curr Opin Immunol. 62:123-130.
PubMed
Amlie-Wolf A
,
Tang M
,
Mlynarski EE
,
Kuksa PP
,
Valladares O
,
Katanić Ž
,
Tsuang D
,
Brown CD
,
Schellenberg GD
,
San Wang L-
. 2018.
INFERNO: inferring the molecular mechanisms of noncoding genetic variants.
.
Nucleic Acids Res. 46(17):8740-8753.
PubMed
Griswold AJ
,
Celis K
,
Bussies PL
,
Rajabli F
,
Whitehead PL
,
Hamilton-Nelson KL
,
Beecham GW
,
Dykxhoorn DM
,
Nuytemans K
,
Wang L
et al.
. 2021.
Increased APOE ε4 expression is associated with the difference in Alzheimer's disease risk from diverse ancestral backgrounds.
.
Alzheimers Dement. 17(7):1179-1188.
PubMed
Xu H
,
O'Reilly M
,
Gibbons GS
,
Changolkar L
,
McBride JD
,
Riddle DM
,
Zhang B
,
Stieber A
,
Nirschl J
,
Kim S-J
et al.
. 2021.
In vitro amplification of pathogenic tau conserves disease-specific bioactive characteristics.
.
Acta Neuropathol. 141(2):193-215.
PubMed
Wolters FJ
,
Yang Q
,
Biggs ML
,
Jakobsdottir J
,
Li S
,
Evans DS
,
Bis JC
,
Harris TB
,
Vasan RS
,
Zilhao NR
et al.
. 2019.
The impact of APOE genotype on survival: Results of 38,537 participants from six population-based cohorts (E2-CHARGE).
.
PLoS One. 14(7):e0219668.
PubMed
Griswold AJ
,
Sivasankaran SK
,
Van Booven D
,
Gardner OK
,
Rajabli F
,
Whitehead PL
,
Hamilton-Nelson KL
,
Adams LD
,
Scott AM
,
Hofmann NK
et al.
. 2020.
Immune and Inflammatory Pathways Implicated by Whole Blood Transcriptomic Analysis in a Diverse Ancestry Alzheimer's Disease Cohort.
.
J Alzheimers Dis. 76(3):1047-1060.
PubMed
Baird DA
,
Liu JZ
,
Zheng J
,
Sieberts SK
,
Perumal T
,
Elsworth B
,
Richardson TG
,
Chen C-Y
,
Carrasquillo MM
,
Allen M
et al.
. 2021.
Identifying drug targets for neurological and psychiatric disease via genetics and the brain transcriptome.
.
PLoS Genet. 17(1):e1009224.
PubMed
He Z
,
Liu L
,
Wang C
,
Le Guen Y
,
Lee J
,
Gogarten S
,
Lu F
,
Montgomery S
,
Tang H
,
Silverman EK
et al.
. 2021.
Identification of putative causal loci in whole-genome sequencing data via knockoff statistics.
.
Nat Commun. 12(1):3152.
PubMed
Lo M-T
,
Kauppi K
,
Fan C-C
,
Sanyal N
,
Reas ET
,
Sundar VS
,
Lee W-C
,
Desikan RS
,
McEvoy LK
,
Chen C-H
. 2019.
Identification of genetic heterogeneity of Alzheimer's disease across age.
.
Neurobiol Aging. 84:243.e1-243.e9.
PubMed
Farron MR
,
Kabeto MU
,
Dey ABallav
,
Banerjee J
,
Levine DA
,
Langa KM
. 2020.
Hypertension and Cognitive Health Among Older Adults in India.
.
J Am Geriatr Soc. 68 Suppl 3:S29-S35.
PubMed
Kuksa PP
,
Li F
,
Kannan S
,
Gregory BD
,
Leung YYee
,
San Wang L-
. 2020.
HiPR: High-throughput probabilistic RNA structure inference.
.
Comput Struct Biotechnol J. 18:1539-1547.
PubMed
Kuksa PP
,
Amlie-Wolf A
,
Hwang Y-C
,
Valladares O
,
Gregory BD
,
San Wang L-
. 2020.
HIPPIE2: a method for fine-scale identification of physically interacting chromatin regions.
.
NAR Genom Bioinform. 2(2):lqaa022.
PubMed
Ewers M
,
Biechele G
,
Suárez-Calvet M
,
Sacher C
,
Blume T
,
Morenas-Rodriguez E
,
Deming Y
,
Piccio L
,
Cruchaga C
,
Kleinberger G
et al.
. 2020.
Higher CSF sTREM2 and microglia activation are associated with slower rates of beta-amyloid accumulation.
.
EMBO Mol Med. 12(9):e12308.
PubMed
Wu HMan
,
Goate AM
,
O'Reilly PF
. 2021.
Heterogeneous effects of genetic risk for Alzheimer's disease on the phenome.
.
Transl Psychiatry. 11(1):406.
PubMed
Smith EE
,
Biessels GJan
,
De Guio F
,
de Leeuw FErik
,
Duchesne S
,
Düring M
,
Frayne R
,
M Ikram A
,
Jouvent E
,
MacIntosh BJ
et al.
. 2019.
Harmonizing brain magnetic resonance imaging methods for vascular contributions to neurodegeneration.
.
Alzheimers Dement (Amst). 11:191-204.
PubMed
Wheeler NR
,
Benchek P
,
Kunkle BW
,
Hamilton-Nelson KL
,
Warfe M
,
Fondran JR
,
Haines JL
,
Bush WS
. 2020.
Hadoop and PySpark for reproducibility and scalability of genomic sequencing studies.
.
Pac Symp Biocomput. 25:523-534.
PubMed
Marioni RE
,
Harris SE
,
Zhang Q
,
McRae AF
,
Hagenaars SP
,
W Hill D
,
Davies G
,
Ritchie CW
,
Gale CR
,
Starr JM
et al.
. 2018.
GWAS on family history of Alzheimer's disease.
.
Transl Psychiatry. 8(1):99.
PubMed
Fulton-Howard B
,
Goate AM
,
Adelson RP
,
Koppel J
,
Gordon ML
,
Barzilai N
,
Atzmon G
,
Davies P
,
Freudenberg-Hua Y
. 2021.
Greater effect of polygenic risk score for Alzheimer's disease among younger cases who are apolipoprotein E-ε4 carriers.
.
Neurobiol Aging. 99:101.e1-101.e9.
PubMed
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