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M
Ma Y
,
Jun GR
,
Chung J
,
Zhang X
,
Kunkle BW
,
Naj AC
,
White CC
,
Bennett DA
,
De Jager PL
,
Mayeux R
et al.
. 2019.
CpG-related SNPs in the MS4A region have a dose-dependent effect on risk of late-onset Alzheimer disease.
.
Aging Cell. 18(4):e12964.
PubMed
L
Lyons CE
,
Zhou X
,
Razzoli M
,
Chen M
,
Xia W
,
Ashe K
,
Zhang B
,
Bartolomucci A
. 2021.
Lifelong chronic psychosocial stress induces a proteomic signature of Alzheimer's disease in wildtype mice.
.
Eur J Neurosci.
PubMed
Lyon MS
,
Andrews SJ
,
Elsworth B
,
Gaunt TR
,
Hemani G
,
Marcora E
. 2021.
The variant call format provides efficient and robust storage of GWAS summary statistics.
.
Genome Biol. 22(1):32.
PubMed
Lobach I
,
Kim I
,
Alekseyenko A
,
Lobach S
,
Zhang L
. 2019.
A simple approximation to bias in the genetic effect estimates when multiple disease states share a clinical diagnosis.
.
Genet Epidemiol. 43(5):522-531.
PubMed
Lo M-T
,
Kauppi K
,
Fan C-C
,
Sanyal N
,
Reas ET
,
Sundar VS
,
Lee W-C
,
Desikan RS
,
McEvoy LK
,
Chen C-H
. 2019.
Identification of genetic heterogeneity of Alzheimer's disease across age.
.
Neurobiol Aging. 84:243.e1-243.e9.
PubMed
Liu Y
,
Wang M
,
Marcora EM
,
Zhang B
,
Goate AM
. 2019.
Promoter DNA hypermethylation - Implications for Alzheimer's disease.
.
Neurosci Lett. 711:134403.
PubMed
Lin H
,
Satizabal C
,
Xie Z
,
Yang Q
,
Huan T
,
Joehanes R
,
Wen C
,
Munson PJ
,
Beiser A
,
Levy D
et al.
. 2017.
Whole blood gene expression and white matter Hyperintensities.
.
Mol Neurodegener. 12(1):67.
PubMed
Li Z
,
Farias FHG
,
Dube U
,
Del-Aguila JL
,
Mihindukulasuriya KA
,
Fernández MVictoria
,
Ibañez L
,
Budde JP
,
Wang F
,
Lake AM
et al.
. 2020.
The TMEM106B FTLD-protective variant, rs1990621, is also associated with increased neuronal proportion.
.
Acta Neuropathol. 139(1):45-61.
PubMed
Leung YYee
,
Valladares O
,
Chou Y-F
,
Lin H-J
,
Kuzma AB
,
Cantwell L
,
Qu L
,
Gangadharan P
,
Salerno WJ
,
Schellenberg GD
et al.
. 2018.
VCPA: genomic Variant Calling pipeline and data management tool for Alzheimer's Disease Sequencing Project.
.
Bioinformatics.
PubMed
Leonenko G
,
Sims R
,
Shoai M
,
Frizzati A
,
Bossù P
,
Spalletta G
,
Fox NC
,
Williams J
,
Hardy J
,
Escott-Price V
. 2019.
Polygenic risk and hazard scores for Alzheimer's disease prediction.
.
Ann Clin Transl Neurol. 6(3):456-465.
PubMed
Lee J
,
Khobragade PY
,
Banerjee J
,
Chien S
,
Angrisani M
,
Perianayagam A
,
Bloom DE
,
Dey AB
. 2020.
Design and Methodology of the Longitudinal Aging Study in India-Diagnostic Assessment of Dementia (LASI-DAD).
.
J Am Geriatr Soc. 68 Suppl 3:S5-S10.
PubMed
Lee J
,
Ganguli M
,
Weerman A
,
Chien S
,
Lee DYoung
,
Varghese M
,
Dey AB
. 2020.
Online Clinical Consensus Diagnosis of Dementia: Development and Validation.
.
J Am Geriatr Soc. 68 Suppl 3:S54-S59.
PubMed
Lee J
,
Dey AB
. 2020.
Introduction to LASI-DAD: The Longitudinal Aging Study in India-Diagnostic Assessment of Dementia.
.
J Am Geriatr Soc. 68 Suppl 3:S3-S4.
PubMed
Laverde-Paz MJuliana
,
Nuytemans K
,
Wang L
,
Vance JM
,
Pericak-Vance MA
,
Dykxhoorn DM
,
Cukier HN
. 2021.
Derivation of stem cell line UMi028-A-2 containing a CRISPR/Cas9 induced Alzheimer's disease risk variant p.S1038C in the TTC3 gene.
.
Stem Cell Res. 52:102258.
PubMed
Larsson SC
,
Traylor M
,
Burgess S
,
Boncoraglio GB
,
Jern C
,
Michaëlsson K
,
Markus HS
. 2019.
Serum magnesium and calcium levels in relation to ischemic stroke: Mendelian randomization study.
.
Neurology. 92(9):e944-e950.
PubMed
Lancour D
,
Dupuis J
,
Mayeux R
,
Haines JL
,
Pericak-Vance MA
,
Schellenberg GC
,
Crovella M
,
Farrer LA
,
Kasif S
. 2020.
Analysis of brain region-specific co-expression networks reveals clustering of established and novel genes associated with Alzheimer disease.
.
Alzheimers Res Ther. 12(1):103.
PubMed
Lananna BV
,
McKee CA
,
King MW
,
Del-Aguila JL
,
Dimitry JM
,
Farias FHG
,
Nadarajah CJ
,
Xiong DD
,
Guo C
,
Cammack AJ
et al.
. 2020.
/YKL-40 is controlled by the astrocyte circadian clock and regulates neuroinflammation and Alzheimer's disease pathogenesis.
.
Sci Transl Med. 12(574)
PubMed
Lagomarsino VN
,
Pearse RV
,
Liu L
,
Hsieh Y-C
,
Fernandez MA
,
Vinton EA
,
Paull D
,
Felsky D
,
Tasaki S
,
Gaiteri C
et al.
. 2021.
Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors.
.
Neuron. 109(21):3402-3420.e9.
PubMed
K
Kunkle BW
,
Schmidt M
,
Klein H-U
,
Naj AC
,
Hamilton-Nelson KL
,
Larson EB
,
Evans DA
,
De Jager PL
,
Crane PK
,
Buxbaum JD
et al.
. 2021.
Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis.
.
JAMA Neurol. 78(1):102-113.
PubMed
Kunkle BW
,
Grenier-Boley B
,
Sims R
,
Bis JC
,
Damotte V
,
Naj AC
,
Boland A
,
Vronskaya M
,
van der Lee SJ
,
Amlie-Wolf A
et al.
. 2019.
Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.
.
Nat Genet. 51(3):414-430.
PubMed
Kunkle BW
,
Jaworski J
,
Barral S
,
Vardarajan B
,
Beecham GW
,
Martin ER
,
Cantwell LS
,
Partch A
,
Bird TD
,
Raskind WH
et al.
. 2016.
Genome-wide linkage analyses of non-Hispanic white families identify novel loci for familial late-onset Alzheimer's disease.
.
Alzheimers Dement. 12(1):2-10.
PubMed
Kunji K
,
Ullah E
,
Nato AQ
,
Wijsman EM
,
Saad M
. 2018.
GIGI-Quick: a fast approach to impute missing genotypes in genome-wide association family data.
.
Bioinformatics. 34(9):1591-1593.
PubMed
Kulminski AM
,
Barochia AV
,
Loika Y
,
Raghavachari N
,
Arbeev KG
,
Wojczynski MK
,
Thyagarajan B
,
Vardarajan BN
,
Christensen K
,
Yashin AI
et al.
. 2018.
The APOE ε4 allele is associated with a reduction in FEV1/FVC in women: A cross-sectional analysis of the Long Life Family Study.
.
PLoS One. 13(11):e0206873.
PubMed
Kulick ER
,
Wellenius GA
,
Boehme AK
,
Joyce NR
,
Schupf N
,
Kaufman JD
,
Mayeux R
,
Sacco RL
,
Manly JJ
,
Elkind MSV
. 2020.
Long-term exposure to air pollution and trajectories of cognitive decline among older adults.
.
Neurology. 94(17):e1782-e1792.
PubMed
Kulick ER
,
Elkind MSV
,
Boehme AK
,
Joyce NR
,
Schupf N
,
Kaufman JD
,
Mayeux R
,
Manly JJ
,
Wellenius GA
. 2020.
Long-term exposure to ambient air pollution, APOE-ε4 status, and cognitive decline in a cohort of older adults in northern Manhattan.
.
Environ Int. 136:105440.
PubMed
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