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Beecham, Gary W
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A
Beecham GW
,
Bis JC
,
Martin ER
,
Choi S-H
,
DeStefano AL
,
van Duijn CM
,
Fornage M
,
Gabriel SB
,
Koboldt DC
,
Larson DE
et al.
. 2017.
The Alzheimer's Disease Sequencing Project: Study design and sample selection.
.
Neurol Genet. 3(5):e194.
PubMed
Rajabli F
,
Feliciano BE
,
Celis K
,
Hamilton-Nelson KL
,
Whitehead PL
,
Adams LD
,
Bussies PL
,
Manrique CP
,
Rodriguez A
,
Rodriguez V
et al.
. 2018.
Ancestral origin of ApoE ε4 Alzheimer disease risk in Puerto Rican and African American populations.
.
PLoS Genet. 14(12):e1007791.
PubMed
D
Marca-Ysabel MVictoria
,
Rajabli F
,
Cornejo-Olivas M
,
Whitehead PG
,
Hofmann NK
,
Manrique MZaida Illa
,
Otani DMartin Vel
,
Neyra AKarina Mil
,
Suarez SCastro
,
Vega MMeza
et al.
. 2021.
Dissecting the role of Amerindian genetic ancestry and the ApoE ε4 allele on Alzheimer disease in an admixed Peruvian population.
.
Neurobiol Aging. 101:298.e11-298.e15.
PubMed
E
Reiman EM
,
Arboleda-Velasquez JF
,
Quiroz YT
,
Huentelman MJ
,
Beach TG
,
Caselli RJ
,
Chen Y
,
Su Y
,
Myers AJ
,
Hardy J
et al.
. 2020.
Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study.
.
Nat Commun. 11(1):667.
PubMed
G
Chauhan G
,
Adams HHH
,
Satizabal CL
,
Bis JC
,
Teumer A
,
Sargurupremraj M
,
Hofer E
,
Trompet S
,
Hilal S
,
Smith AVernon
et al.
. 2019.
Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting.
.
Neurology.
PubMed
Kunkle BW
,
Grenier-Boley B
,
Sims R
,
Bis JC
,
Damotte V
,
Naj AC
,
Boland A
,
Vronskaya M
,
van der Lee SJ
,
Amlie-Wolf A
et al.
. 2019.
Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.
.
Nat Genet. 51(3):414-430.
PubMed
Kunkle BW
,
Jaworski J
,
Barral S
,
Vardarajan B
,
Beecham GW
,
Martin ER
,
Cantwell LS
,
Partch A
,
Bird TD
,
Raskind WH
et al.
. 2016.
Genome-wide linkage analyses of non-Hispanic white families identify novel loci for familial late-onset Alzheimer's disease.
.
Alzheimers Dement. 12(1):2-10.
PubMed
I
Griswold AJ
,
Sivasankaran SK
,
Van Booven D
,
Gardner OK
,
Rajabli F
,
Whitehead PL
,
Hamilton-Nelson KL
,
Adams LD
,
Scott AM
,
Hofmann NK
et al.
. 2020.
Immune and Inflammatory Pathways Implicated by Whole Blood Transcriptomic Analysis in a Diverse Ancestry Alzheimer's Disease Cohort.
.
J Alzheimers Dis. 76(3):1047-1060.
PubMed
Griswold AJ
,
Celis K
,
Bussies PL
,
Rajabli F
,
Whitehead PL
,
Hamilton-Nelson KL
,
Beecham GW
,
Dykxhoorn DM
,
Nuytemans K
,
Wang L
et al.
. 2021.
Increased APOE ε4 expression is associated with the difference in Alzheimer's disease risk from diverse ancestral backgrounds.
.
Alzheimers Dement. 17(7):1179-1188.
PubMed
L
Rajabli F
,
Feliciano-Astacio BE
,
Cukier HN
,
Wang L
,
Griswold AJ
,
Hamilton-Nelson KL
,
Adams LD
,
Rodriguez VC
,
Mena PR
,
Tejada S
et al.
. 2021.
Linkage of Alzheimer disease families with Puerto Rican ancestry identifies a chromosome 9 locus.
.
Neurobiol Aging. 104:115.e1-115.e7.
PubMed
P
Feliciano-Astacio BE
,
Celis K
,
Ramos J
,
Rajabli F
,
Adams LDeon
,
Rodriguez A
,
Rodriguez V
,
Bussies PL
,
Sierra C
,
Manrique P
et al.
. 2019.
The Puerto Rico Alzheimer Disease Initiative (PRADI): A Multisource Ascertainment Approach.
.
Front Genet. 10:538.
PubMed
R
Beecham GW
,
Vardarajan B
,
Blue E
,
Bush W
,
Jaworski J
,
Barral S
,
DeStefano A
,
Hamilton-Nelson K
,
Kunkle B
,
Martin ER
et al.
. 2018.
Rare genetic variation implicated in non-Hispanic white families with Alzheimer disease.
.
Neurol Genet. 4(6):e286.
PubMed
Gardner OK
,
Wang L
,
Van Booven D
,
Whitehead PL
,
Hamilton-Nelson KL
,
Adams LD
,
Starks TD
,
Hofmann NK
,
Vance JM
,
Cuccaro ML
et al.
. 2019.
RNA editing alterations in a multi-ethnic Alzheimer disease cohort converge on immune and endocytic molecular pathways.
.
Hum Mol Genet. 28(18):3053-3061.
PubMed
U
Bussies PL
,
Rajabli F
,
Griswold A
,
Dorfsman DA
,
Whitehead P
,
Adams LD
,
Mena PR
,
Cuccaro M
,
Haines JL
,
Byrd GS
et al.
. 2020.
Use of local genetic ancestry to assess -523' and risk for Alzheimer disease.
.
Neurol Genet. 6(2):e404.
PubMed
W
Bis JC
,
Jian X
,
Kunkle BW
,
Chen Y
,
Hamilton-Nelson KL
,
Bush WS
,
Salerno WJ
,
Lancour D
,
Ma Y
,
Renton AE
et al.
. 2018.
Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation.
.
Mol Psychiatry.
PubMed
Vardarajan BN
,
Barral S
,
Jaworski J
,
Beecham GW
,
Blue E
,
Tosto G
,
Reyes-Dumeyer D
,
Medrano M
,
Lantigua R
,
Naj A
et al.
. 2018.
Whole genome sequencing of Caribbean Hispanic families with late-onset Alzheimer's disease.
.
Ann Clin Transl Neurol. 5(4):406-417.
PubMed
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