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Genome-Wide Association Study
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A
Adams SL
,
Benayoun L
,
Tilton K
,
Chavez OR
,
Himali JJ
,
Blusztajn JKrzysztof
,
Seshadri S
,
Delalle I
. 2017.
Methionine Sulfoxide Reductase-B3 (MsrB3) Protein Associates with Synaptic Vesicles and its Expression Changes in the Hippocampi of Alzheimer's Disease Patients.
.
J Alzheimers Dis. 60(1):43-56.
PubMed
Amlie-Wolf A
,
Kuksa PP
,
Lee C-Y
,
Mlynarski E
,
Leung YYee
,
San Wang L-
. 2021.
Using INFERNO to Infer the Molecular Mechanisms Underlying Noncoding Genetic Associations.
.
Methods Mol Biol. 2254:73-91.
PubMed
Amlie-Wolf A
,
Tang M
,
Mlynarski EE
,
Kuksa PP
,
Valladares O
,
Katanić Ž
,
Tsuang D
,
Brown CD
,
Schellenberg GD
,
San Wang L-
. 2018.
INFERNO: inferring the molecular mechanisms of noncoding genetic variants.
.
Nucleic Acids Res. 46(17):8740-8753.
PubMed
Andrews SJ
,
Fulton-Howard B
,
Goate A
. 2020.
Interpretation of risk loci from genome-wide association studies of Alzheimer's disease.
.
Lancet Neurol. 19(4):326-335.
PubMed
Andrews SJ
,
Goate A
,
Anstey KJ
. 2020.
Association between alcohol consumption and Alzheimer's disease: A Mendelian randomization study.
.
Alzheimers Dement. 16(2):345-353.
PubMed
Armstrong NJ
,
Mather KA
,
Sargurupremraj M
,
Knol MJ
,
Malik R
,
Satizabal CL
,
Yanek LR
,
Wen W
,
Gudnason VG
,
Dueker ND
et al.
. 2020.
Common Genetic Variation Indicates Separate Causes for Periventricular and Deep White Matter Hyperintensities.
.
Stroke. 51(7):2111-2121.
PubMed
B
Baird DA
,
Liu JZ
,
Zheng J
,
Sieberts SK
,
Perumal T
,
Elsworth B
,
Richardson TG
,
Chen C-Y
,
Carrasquillo MM
,
Allen M
et al.
. 2021.
Identifying drug targets for neurological and psychiatric disease via genetics and the brain transcriptome.
.
PLoS Genet. 17(1):e1009224.
PubMed
Barral S
,
Cheng R
,
Reitz C
,
Vardarajan B
,
Lee J
,
Kunkle B
,
Beecham G
,
Cantwell LS
,
Pericak-Vance MA
,
Farrer LA
et al.
. 2015.
Linkage analyses in Caribbean Hispanic families identify novel loci associated with familial late-onset Alzheimer's disease.
.
Alzheimers Dement. 11(12):1397-1406.
PubMed
Bentley AR
,
Sung YJ
,
Brown MR
,
Winkler TW
,
Kraja AT
,
Ntalla I
,
Schwander K
,
Chasman DI
,
Lim E
,
Deng X
et al.
. 2019.
Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
.
Nat Genet. 51(4):636-648.
PubMed
Blue EE
,
Thornton TA
,
Kooperberg C
,
Liu S
,
Wactawski-Wende J
,
Manson JA
,
Kuller L
,
Hayden K
,
Reiner AP
. 2021.
Non-coding variants in MYH11, FZD3, and SORCS3 are associated with dementia in women.
.
Alzheimers Dement. 17(2):215-225.
PubMed
Blue EE
,
Bis JC
,
Dorschner MO
,
Tsuang DW
,
Barral SM
,
Beecham G
,
Below JE
,
Bush WS
,
Butkiewicz M
,
Cruchaga C
et al.
. 2018.
Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer's Disease Sequencing Project.
.
Dement Geriatr Cogn Disord. 45(1-2):1-17.
PubMed
C
Chia R
,
Sabir MS
,
Bandres-Ciga S
,
Saez-Atienzar S
,
Reynolds RH
,
Gustavsson E
,
Walton RL
,
Ahmed S
,
Viollet C
,
Ding J
et al.
. 2021.
Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture.
.
Nat Genet. 53(3):294-303.
PubMed
D
Damotte V
,
van der Lee SJ
,
Chouraki V
,
Grenier-Boley B
,
Simino J
,
Adams H
,
Tosto G
,
White C
,
Terzikhan N
,
Cruchaga C
et al.
. 2021.
Plasma amyloid β levels are driven by genetic variants near APOE, BACE1, APP, PSEN2: A genome-wide association study in over 12,000 non-demented participants.
.
Alzheimers Dement. 17(10):1663-1674.
PubMed
de Rojas I
,
Moreno-Grau S
,
Tesi N
,
Grenier-Boley B
,
Andrade V
,
Jansen IE
,
Pedersen NL
,
Stringa N
,
Zettergren A
,
Hernández I
et al.
. 2021.
Common variants in Alzheimer's disease and risk stratification by polygenic risk scores.
.
Nat Commun. 12(1):3417.
PubMed
de Vries PS
,
Sabater-Lleal M
,
Huffman JE
,
Marten J
,
Song C
,
Pankratz N
,
Bartz TM
,
de Haan HG
,
Delgado GE
,
Eicher JD
et al.
. 2019.
A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology.
.
Blood. 133(9):967-977.
PubMed
Deming Y
,
Dumitrescu L
,
Barnes LL
,
Thambisetty M
,
Kunkle B
,
Gifford KA
,
Bush WS
,
Chibnik LB
,
Mukherjee S
,
De Jager PL
et al.
. 2018.
Sex-specific genetic predictors of Alzheimer's disease biomarkers.
.
Acta Neuropathol. 136(6):857-872.
PubMed
Dumitrescu L
,
Mahoney ER
,
Mukherjee S
,
Lee ML
,
Bush WS
,
Engelman CD
,
Lu Q
,
Fardo DW
,
Trittschuh EH
,
Mez J
et al.
. 2020.
Genetic variants and functional pathways associated with resilience to Alzheimer's disease.
.
Brain. 143(8):2561-2575.
PubMed
F
Fan CChieh
,
Banks SJ
,
Thompson WK
,
Chen C-H
,
McEvoy LK
,
Tan CHong
,
Kukull W
,
Bennett DA
,
Farrer LA
,
Mayeux R
et al.
. 2020.
Sex-dependent autosomal effects on clinical progression of Alzheimer's disease.
.
Brain. 143(7):2272-2280.
PubMed
G
Grasby KL
,
Jahanshad N
,
Painter JN
,
Colodro-Conde L
,
Bralten J
,
Hibar DP
,
Lind PA
,
Pizzagalli F
,
Ching CRK
,
McMahon MAgnes B
et al.
. 2020.
The genetic architecture of the human cerebral cortex.
.
Science. 367(6484)
PubMed
Guerreiro R
,
Gibbons E
,
Tábuas-Pereira M
,
Kun-Rodrigues C
,
Santo GC
,
Bras J
. 2020.
Genetic architecture of common non-Alzheimer's disease dementias.
.
Neurobiol Dis. 142:104946.
PubMed
H
Hartl D
,
May P
,
Gu W
,
Mayhaus M
,
Pichler S
,
Spaniol C
,
Glaab E
,
Bobbili DReddy
,
Antony P
,
Koegelsberger S
et al.
. 2020.
A rare loss-of-function variant of ADAM17 is associated with late-onset familial Alzheimer disease.
.
Mol Psychiatry. 25(3):629-639.
PubMed
He Z
,
Liu L
,
Wang C
,
Le Guen Y
,
Lee J
,
Gogarten S
,
Lu F
,
Montgomery S
,
Tang H
,
Silverman EK
et al.
. 2021.
Identification of putative causal loci in whole-genome sequencing data via knockoff statistics.
.
Nat Commun. 12(1):3152.
PubMed
Hofer E
,
Roshchupkin GV
,
Adams HHH
,
Knol MJ
,
Lin H
,
Li S
,
Zare H
,
Ahmad S
,
Armstrong NJ
,
Satizabal CL
et al.
. 2020.
Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults.
.
Nat Commun. 11(1):4796.
PubMed
Horimoto ARVR
,
Xue D
,
Thornton TA
,
Blue EE
. 2021.
Admixture mapping reveals the association between Native American ancestry at 3q13.11 and reduced risk of Alzheimer's disease in Caribbean Hispanics.
.
Alzheimers Res Ther. 13(1):122.
PubMed
Hu Y
,
Li M
,
Lu Q
,
Weng H
,
Wang J
,
Zekavat SM
,
Yu Z
,
Li B
,
Gu J
,
Muchnik S
et al.
. 2019.
A statistical framework for cross-tissue transcriptome-wide association analysis.
.
Nat Genet. 51(3):568-576.
PubMed
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