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De Jager, Philip L
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2021
Patrick E
,
Olah M
,
Taga M
,
Klein H-U
,
Xu J
,
White CC
,
Felsky D
,
Agrawal S
,
Gaiteri C
,
Chibnik LB
et al.
. 2021.
A cortical immune network map identifies distinct microglial transcriptional programs associated with β-amyloid and Tau pathologies.
.
Transl Psychiatry. 11(1):50.
PubMed
De Jager PL
. 2021.
Deconstructing the epigenomic architecture of human neurodegeneration.
.
Neurobiol Dis. 153:105331.
PubMed
Robins C
,
Liu Y
,
Fan W
,
Duong DM
,
Meigs J
,
Harerimana NV
,
Gerasimov ES
,
Dammer EB
,
Cutler DJ
,
Beach TG
et al.
. 2021.
Genetic control of the human brain proteome.
.
Am J Hum Genet. 108(3):400-410.
PubMed
Wang H
,
Bennett DA
,
De Jager PL
,
Zhang Q-Y
,
Zhang H-Y
. 2021.
Genome-wide epistasis analysis for Alzheimer's disease and implications for genetic risk prediction.
.
Alzheimers Res Ther. 13(1):55.
PubMed
Baird DA
,
Liu JZ
,
Zheng J
,
Sieberts SK
,
Perumal T
,
Elsworth B
,
Richardson TG
,
Chen C-Y
,
Carrasquillo MM
,
Allen M
et al.
. 2021.
Identifying drug targets for neurological and psychiatric disease via genetics and the brain transcriptome.
.
PLoS Genet. 17(1):e1009224.
PubMed
Wingo AP
,
Liu Y
,
Gerasimov ES
,
Gockley J
,
Logsdon BA
,
Duong DM
,
Dammer EB
,
Robins C
,
Beach TG
,
Reiman EM
et al.
. 2021.
Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer's disease pathogenesis.
.
Nat Genet. 53(2):143-146.
PubMed
Ramos-Miguel A
,
Jones AA
,
Petyuk VA
,
Barakauskas VE
,
Barr AM
,
Leurgans SE
,
De Jager PL
,
Casaletto KB
,
Schneider JA
,
Bennett DA
et al.
. 2021.
Proteomic identification of select protein variants of the SNARE interactome associated with cognitive reserve in a large community sample.
.
Acta Neuropathol. 141(5):755-770.
PubMed
Lagomarsino VN
,
Pearse RV
,
Liu L
,
Hsieh Y-C
,
Fernandez MA
,
Vinton EA
,
Paull D
,
Felsky D
,
Tasaki S
,
Gaiteri C
et al.
. 2021.
Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors.
.
Neuron. 109(21):3402-3420.e9.
PubMed
2020
Raghavan NS
,
Dumitrescu L
,
Mormino E
,
Mahoney ER
,
Lee AJ
,
Gao Y
,
Bilgel M
,
Goldstein D
,
Harrison T
,
Engelman CD
et al.
. 2020.
Association Between Common Variants in RBFOX1, an RNA-Binding Protein, and Brain Amyloidosis in Early and Preclinical Alzheimer Disease.
.
JAMA Neurol. 77(10):1288-1298.
PubMed
Ouellette AR
,
Neuner SM
,
Dumitrescu L
,
Anderson LC
,
Gatti DM
,
Mahoney ER
,
Bubier JA
,
Churchill G
,
Peters L
,
Huentelman MJ
et al.
. 2020.
Cross-Species Analyses Identify Dlgap2 as a Regulator of Age-Related Cognitive Decline and Alzheimer's Dementia.
.
Cell Rep. 32(9):108091.
PubMed
Reiman EM
,
Arboleda-Velasquez JF
,
Quiroz YT
,
Huentelman MJ
,
Beach TG
,
Caselli RJ
,
Chen Y
,
Su Y
,
Myers AJ
,
Hardy J
et al.
. 2020.
Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study.
.
Nat Commun. 11(1):667.
PubMed
Mukherjee S
,
Mez J
,
Trittschuh EH
,
Saykin AJ
,
Gibbons LE
,
Fardo DW
,
Wessels M
,
Bauman J
,
Moore M
,
Choi S-E
et al.
. 2020.
Genetic data and cognitively defined late-onset Alzheimer's disease subgroups.
.
Mol Psychiatry. 25(11):2942-2951.
PubMed
Tang M
,
Alaniz MEugenia
,
Felsky D
,
Vardarajan B
,
Reyes-Dumeyer D
,
Lantigua R
,
Medrano M
,
Bennett DA
,
De Jager PL
,
Mayeux R
et al.
. 2020.
Synonymous variants associated with Alzheimer disease in multiplex families.
.
Neurol Genet. 6(4):e450.
PubMed
2019
Ma Y
,
Jun GR
,
Zhang X
,
Chung J
,
Naj AC
,
Chen Y
,
Bellenguez C
,
Hamilton-Nelson K
,
Martin ER
,
Kunkle BW
et al.
. 2019.
Analysis of Whole-Exome Sequencing Data for Alzheimer Disease Stratified by APOE Genotype.
.
JAMA Neurol.
PubMed
Ma Y
,
Jun GR
,
Chung J
,
Zhang X
,
Kunkle BW
,
Naj AC
,
White CC
,
Bennett DA
,
De Jager PL
,
Mayeux R
et al.
. 2019.
CpG-related SNPs in the MS4A region have a dose-dependent effect on risk of late-onset Alzheimer disease.
.
Aging Cell. 18(4):e12964.
PubMed
Chauhan G
,
Adams HHH
,
Satizabal CL
,
Bis JC
,
Teumer A
,
Sargurupremraj M
,
Hofer E
,
Trompet S
,
Hilal S
,
Smith AVernon
et al.
. 2019.
Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting.
.
Neurology.
PubMed
Satizabal CL
,
Adams HHH
,
Hibar DP
,
White CC
,
Knol MJ
,
Stein JL
,
Scholz M
,
Sargurupremraj M
,
Jahanshad N
,
Roshchupkin GV
et al.
. 2019.
Genetic architecture of subcortical brain structures in 38,851 individuals.
.
Nat Genet. 51(11):1624-1636.
PubMed
van der Lee SJ
,
Knol MJ
,
Chauhan G
,
Satizabal CL
,
Smith AVernon
,
Hofer E
,
Bis JC
,
Hibar DP
,
Hilal S
,
van den Akker EB
et al.
. 2019.
A genome-wide association study identifies genetic loci associated with specific lobar brain volumes.
.
Commun Biol. 2:285.
PubMed
Dumitrescu L
,
Barnes LL
,
Thambisetty M
,
Beecham G
,
Kunkle B
,
Bush WS
,
Gifford KA
,
Chibnik LB
,
Mukherjee S
,
De Jager PL
et al.
. 2019.
Sex differences in the genetic predictors of Alzheimer's pathology.
.
Brain. 142(9):2581-2589.
PubMed
2018
Deming Y
,
Dumitrescu L
,
Barnes LL
,
Thambisetty M
,
Kunkle B
,
Gifford KA
,
Bush WS
,
Chibnik LB
,
Mukherjee S
,
De Jager PL
et al.
. 2018.
Sex-specific genetic predictors of Alzheimer's disease biomarkers.
.
Acta Neuropathol. 136(6):857-872.
PubMed
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