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Biblio

Author Title [ Type(Desc)] Year
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Journal Article
Andrews SJ, Fulton-Howard B, O'Reilly P, Marcora E, Goate AM.  2021.  Causal Associations Between Modifiable Risk Factors and the Alzheimer's Phenome.. Ann Neurol. 89(1):54-65.
Fernández MV, Budde J, Del-Aguila JL, Ibañez L, Deming Y, Harari O, Norton J, Morris JC, Goate AM, Cruchaga C.  2018.  Evaluation of Gene-Based Family-Based Methods to Detect Novel Genes Associated With Familial Late Onset Alzheimer Disease.. Front Neurosci. 12:209.
Baker E, Sims R, Leonenko G, Frizzati A, Harwood JC, Grozeva D, Morgan K, Passmore P, Holmes C, Powell J et al..  2019.  Gene-based analysis in HRC imputed genome wide association data identifies three novel genes for Alzheimer's disease.. PLoS One. 14(7):e0218111.
Neuner SM, Tcw J, Goate AM.  2020.  Genetic architecture of Alzheimer's disease.. Neurobiol Dis. 143:104976.
Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A et al..  2019.  Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.. Nat Genet. 51(3):414-430.
Kunkle BW, Jaworski J, Barral S, Vardarajan B, Beecham GW, Martin ER, Cantwell LS, Partch A, Bird TD, Raskind WH et al..  2016.  Genome-wide linkage analyses of non-Hispanic white families identify novel loci for familial late-onset Alzheimer's disease.. Alzheimers Dement. 12(1):2-10.
Fulton-Howard B, Goate AM, Adelson RP, Koppel J, Gordon ML, Barzilai N, Atzmon G, Davies P, Freudenberg-Hua Y.  2021.  Greater effect of polygenic risk score for Alzheimer's disease among younger cases who are apolipoprotein E-ε4 carriers.. Neurobiol Aging. 99:101.e1-101.e9.
Marioni RE, Harris SE, Zhang Q, McRae AF, Hagenaars SP, W Hill D, Davies G, Ritchie CW, Gale CR, Starr JM et al..  2018.  GWAS on family history of Alzheimer's disease.. Transl Psychiatry. 8(1):99.
Wu HMan, Goate AM, O'Reilly PF.  2021.  Heterogeneous effects of genetic risk for Alzheimer's disease on the phenome.. Transl Psychiatry. 11(1):406.
Novikova G, Kapoor M, Tcw J, Abud EM, Efthymiou AG, Chen SX, Cheng H, Fullard JF, Bendl J, Liu Y et al..  2021.  Integration of Alzheimer's disease genetics and myeloid genomics identifies disease risk regulatory elements and genes.. Nat Commun. 12(1):1610.
Barral S, Cheng R, Reitz C, Vardarajan B, Lee J, Kunkle B, Beecham G, Cantwell LS, Pericak-Vance MA, Farrer LA et al..  2015.  Linkage analyses in Caribbean Hispanic families identify novel loci associated with familial late-onset Alzheimer's disease.. Alzheimers Dement. 11(12):1397-1406.
Podleśny-Drabiniok A, Marcora E, Goate AM.  2020.  Microglial Phagocytosis: A Disease-Associated Process Emerging from Alzheimer's Disease Genetics.. Trends Neurosci. 43(12):965-979.
Kunkle BW, Schmidt M, Klein H-U, Naj AC, Hamilton-Nelson KL, Larson EB, Evans DA, De Jager PL, Crane PK, Buxbaum JD et al..  2021.  Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis.. JAMA Neurol. 78(1):102-113.
Liu Y, Wang M, Marcora EM, Zhang B, Goate AM.  2019.  Promoter DNA hypermethylation - Implications for Alzheimer's disease.. Neurosci Lett. 711:134403.
Zhao L, Zhang Z, Rodriguez SMBarral, Vardarajan BN, Renton AE, Goate AM, Mayeux R, Wang GT, Leal SM.  2020.  A quantitative trait rare variant nonparametric linkage method with application to age-at-onset of Alzheimer's disease.. Eur J Hum Genet. 28(12):1734-1742.
Zhang Q, Sidorenko J, Couvy-Duchesne B, Marioni RE, Wright MJ, Goate AM, Marcora E, Huang K-L, Porter T, Laws SM et al..  2020.  Risk prediction of late-onset Alzheimer's disease implies an oligogenic architecture.. Nat Commun. 11(1):4799.
Dumitrescu L, Barnes LL, Thambisetty M, Beecham G, Kunkle B, Bush WS, Gifford KA, Chibnik LB, Mukherjee S, De Jager PL et al..  2019.  Sex differences in the genetic predictors of Alzheimer's pathology.. Brain. 142(9):2581-2589.
Deming Y, Dumitrescu L, Barnes LL, Thambisetty M, Kunkle B, Gifford KA, Bush WS, Chibnik LB, Mukherjee S, De Jager PL et al..  2018.  Sex-specific genetic predictors of Alzheimer's disease biomarkers.. Acta Neuropathol. 136(6):857-872.
Hsu S, Pimenova AA, Hayes K, Villa JA, Rosene MJ, Jere M, Goate AM, Karch CM.  2020.  Systematic validation of variants of unknown significance in APP, PSEN1 and PSEN2.. Neurobiol Dis. 139:104817.

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