Dataset

NG00068 - ADC4 - Alzheimer Disease Center Dataset 4

Overview

The NIA ADC cohort included subjects ascertained and evaluated by the clinical and neuropathology cores of the 39 past and present NIA-funded Alzheimer's Disease Centers (ADC).  Data collection is coordinated by the National Alzheimer’s Coordinating Center (NACC).  NACC coordinates collection of phenotype data from the ADCs, cleans all data, coordinates implementation of definitions of AD cases and controls, and coordinates collection of samples. Biological specimens are collected, stored, and distributed by the National Cell Repository for Alzheimer’s Disease (NCRAD).

This GWAS dataset, ADC4, is the fourth set of ADC genotyped subjects used by the Alzheimer's Disease Genetics Consortium (ADGC) to identify genes associated with an increased risk of developing late-onset Alzheimer’s disease (LOAD). This data was first published in Kunkle et al. For deeper phenotypes, contact NACC.

Detailed information about the dataset is provided in the following document: NG00068_ADC4_README.txt

Molecular Data Type

Disease

AD
Submission date: 
12/18/2018
Samples

Cases- 430
Controls- 372
MCI- 106
NA/Unknown- 146

Total- 1054

Phenotypes
Markers

639151

Platform