SNP rs34404554

ATCCAGAGGTACTGTCTCCCCATAG[G/C]AGCTAGGCTGGAGTGAAGGAACAGG

Genomic Context

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Variant Effect Impact (snpEff)

  • High
  • Moderate
  • Low
  • Modifier
  • Not Reported
  • Reference Allele: C
  • Minor Allele/Frequency: G/0.1096
  • Variant Class: single nucleotide variant
  • Closest Gene: TOMM40

Genome-wide significance

NIAGADS: Alzheimer's Disease

NIAGADS AD GWAS summary statistics datasets in which SNP rs34404554 has a genome-wide significance supported by a p-value ≤ 5 x 10-8.

For exome array studies, a cutoff of p-value < 1 x 10-3 was used.

See methods for more information.

Click on accession numbers to view a detailed report about the dataset or to request access to the data.

To view functional genomics annotations on the genome browser, first select tracks in the table below and then use the provided button to load the tracks on the browser.

p-Value Allele Track Accession Mapped From Get SNPs
1e-466 C
IGAP 2013: Stage 1
summary statistics for IGAP (2013): stage 1
NG00036 N/A
9.55e-71 C
ADGC Age of Onset LOAD
GWAS summary statistics for age of onset in ADGC LOAD GWAS datasets, after adjustment for sex, APOE ε4 number, and population stratification.
NG00048 chr19:45395909

NIAGADS: Related Neuropathologies

NIAGADS non-AD (related neuropathology) GWAS summary statistics datasets in which SNP rs34404554 has a genome-wide significance supported by a p-value ≤ 5 x 10-8.

For exome array studies, a cutoff of p-value < 1 x 10-3 was used.

See methods for more information.

Click on accession numbers to view a detailed report about the dataset or to request access to the data.

To view functional genomics annotations on the genome browser, first select tracks in the table below and then use the provided button to load the tracks on the browser.

p-Value Allele Track Accession Mapped From Get SNPs
1.00e-39 G
CSF: Aβ₄₂
GWAS summary statistics for CSF beta-amyloid 42 (AΒ42) levels, after adjustment for age, sex, and population stratification.
NG00049 N/A
1.32e-16 G
CSF: ptau
GWAS summary statistics for CSF tau phosphorylated at threonine 181 (ptau) levels, after adjustment for age, sex, and population stratification.
NG00049 N/A
3.55e-16 G
CSF: tau
GWAS summary statistics for CSF tau levels, after adjustment for age, sex, and population stratification.
NG00049 N/A

NHGRI: Alzheimer's Disease

NHGRI: Other Traits

Predicted Effects