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MS4A6A - ENSG00000110077

membrane spanning 4-domains A6A

Also known as: CD20L3

Location: chr11:59,939,081-59,952,139 reverse strand

Gene Type: protein coding

More information
NCBI Gene
64231
HUGO
HGNC:13375
Ensembl
ENSG00000110077
VEGA
OTTHUMG00000167241
OMIM
606548
UniProtKB
Q9H2W1

Genomic Context

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Gene-based Trait Associations

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ADSP WES: Alzheimer's Disease ADSP

Results from gene-level rare and functional variant aggregation tests for association to AD supported by significane of p < 0.5 / #genes.

Individual score test statistics for rare, predicted functional, and loss of function variants colocated with the gene were aggregated to compute gene level p-values.

See NIAGADS Accession NG00065 for more information.

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Accession Population N SNPs p-value Sign. Level rho CMAF CMAC Covariates Variant Filter Caveats
NG00065 European 29 0.383 N/A 0 0.025 520.6 PCs and sequencing center VEP MOD-HIGH N/A
NG00065 Caribbean Hispanic 3 0.485 N/A 0 7.6e-03 6.0 PCs and sequencing center VEP HIGH
NG00065 Caribbean Hispanic 3 0.485 N/A 0 7.6e-03 6.0 PCs and sequencing center LOF
NG00065 European 6 0.488 N/A 1 6.5e-03 135.0 PCs and sequencing center LOF N/A
NG00065 European 6 0.488 N/A 1 6.5e-03 135.1 PCs and sequencing center VEP HIGH N/A
NG00065 Meta 32 0.495 N/A 0 0.025 536.6 PCs and sequencing center VEP MOD-HIGH N/A
NG00065 Caribbean Hispanic 3 0.513 N/A 0 7.6e-03 6.0 PCs, sequencing center, sex, and age at AD onset or last-known dementia-free age (for controls) LOF
NG00065 Caribbean Hispanic 3 0.513 N/A 0 7.6e-03 6.0 PCs, sequencing center, sex, and age at AD onset or last-known dementia-free age (for controls) VEP HIGH
NG00065 Meta 32 0.515 N/A 1 0.025 536.6 PCs, sequencing center, sex, and age at AD onset or last-known dementia-free age (for controls) VEP MOD-HIGH N/A
NG00065 Caribbean Hispanic 3 0.516 N/A 1 7.6e-03 6.0 PCs, sequencing center, sex, age at AD onset or last-known dementia-free age (for controls), and APOE E2 and E4 genotypes VEP HIGH
NG00065 Caribbean Hispanic 3 0.518 N/A 0 7.6e-03 6.0 PCs, sequencing center, sex, age at AD onset or last-known dementia-free age (for controls), and APOE E2 and E4 genotypes LOF
NG00065 Meta 32 0.549 N/A 1 0.025 536.6 PCs, sequencing center, sex, age at AD onset or last-known dementia-free age (for controls), and APOE E2 and E4 genotypes VEP MOD-HIGH N/A
NG00065 European 6 0.549 N/A 1 6.5e-03 135.0 PCs, sequencing center, sex, and age at AD onset or last-known dementia-free age (for controls) LOF N/A
NG00065 European 6 0.549 N/A 1 6.5e-03 135.1 PCs, sequencing center, sex, and age at AD onset or last-known dementia-free age (for controls) VEP HIGH N/A
NG00065 European 29 0.552 N/A 1 0.025 520.6 PCs, sequencing center, sex, and age at AD onset or last-known dementia-free age (for controls) VEP MOD-HIGH N/A
NG00065 European 6 0.571 N/A 1 6.5e-03 135.1 PCs, sequencing center, sex, age at AD onset or last-known dementia-free age (for controls), and APOE E2 and E4 genotypes VEP HIGH N/A
NG00065 European 6 0.571 N/A 1 6.5e-03 135.0 PCs, sequencing center, sex, age at AD onset or last-known dementia-free age (for controls), and APOE E2 and E4 genotypes LOF N/A
NG00065 Caribbean Hispanic 5 0.573 N/A 0 0.020 16.0 PCs and sequencing center VEP MOD-HIGH N/A
NG00065 Meta 8 0.574 N/A 1 6.5e-03 141.0 PCs and sequencing center LOF N/A
NG00065 Meta 8 0.574 N/A 1 6.5e-03 141.1 PCs and sequencing center VEP HIGH N/A
NG00065 European 29 0.595 N/A 1 0.025 520.6 PCs, sequencing center, sex, age at AD onset or last-known dementia-free age (for controls), and APOE E2 and E4 genotypes VEP MOD-HIGH N/A
NG00065 Caribbean Hispanic 5 0.609 N/A 0 0.020 16.0 PCs, sequencing center, sex, and age at AD onset or last-known dementia-free age (for controls) VEP MOD-HIGH N/A
NG00065 Caribbean Hispanic 5 0.609 N/A 0 0.020 16.0 PCs, sequencing center, sex, age at AD onset or last-known dementia-free age (for controls), and APOE E2 and E4 genotypes VEP MOD-HIGH N/A
NG00065 Meta 8 0.657 N/A 1 6.5e-03 141.0 PCs, sequencing center, sex, and age at AD onset or last-known dementia-free age (for controls) LOF N/A
NG00065 Meta 8 0.657 N/A 1 6.5e-03 141.1 PCs, sequencing center, sex, and age at AD onset or last-known dementia-free age (for controls) VEP HIGH N/A
NG00065 Meta 8 0.672 N/A 1 6.5e-03 141.1 PCs, sequencing center, sex, age at AD onset or last-known dementia-free age (for controls), and APOE E2 and E4 genotypes VEP HIGH N/A
NG00065 Meta 8 0.672 N/A 1 6.5e-03 141.0 PCs, sequencing center, sex, age at AD onset or last-known dementia-free age (for controls), and APOE E2 and E4 genotypes LOF N/A

Genetic Variation and Variant-based Trait Associations (GWAS)

Variants contained within the MS4A6A gene.

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The MS4A6A gene contains 1,029 variants records (corresponding to 982 unique genomic positions).

The following variants, contained within ±100kb of MS4A6A, have been found to be associated with Alzheimer's disease in a GWAS study:

NIAGADS GWAS: Alzheimer's Disease

Variants contained within ±100kb of MS4A6A that have genome-wide significance in a NIAGADS Alzheimer's Disease GWAS summary statistics dataset; supported by a p-value < 5 x 10-8. For exome array studies, a cutoff of p-value < 1 x 10-3 was used.

Click on accession numbers to view a detailed report about the dataset or to request access to the data.

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Login in to select variants and add them to your basket.

Relative Position Variant ADSP? Allele p-Value Track Accession
upstream G 6.1e-16 IGAP 2013: Stages 1 and 2 NG00036
upstream A 1.3e-15 IGAP 2013: Stages 1 and 2 NG00036
downstream A 1.8e-15 IGAP 2013: Stages 1 and 2 NG00036
upstream C 1.9e-15 IGAP 2013: Stages 1 and 2 NG00036
upstream A 2.1e-15 IGAP 2013: Stages 1 and 2 NG00036
upstream C 2.5e-15 IGAP 2013: Stages 1 and 2 NG00036
upstream T 3.0e-15 IGAP 2013: Stages 1 and 2 NG00036
upstream T 5.6e-15 IGAP 2013: Stages 1 and 2 NG00036
upstream T 7.3e-15 IGAP 2013: Stages 1 and 2 NG00036
upstream C 7.6e-15 IGAP 2013: Stages 1 and 2 NG00036
upstream C 8.0e-15 IGAP 2013: Stages 1 and 2 NG00036
upstream T 8.7e-15 IGAP 2013: Stages 1 and 2 NG00036
upstream G 9.7e-15 IGAP 2013: Stages 1 and 2 NG00036
upstream G 1.1e-14 IGAP 2013: Stages 1 and 2 NG00036
upstream A 1.2e-14 IGAP 2013: Stages 1 and 2 NG00036
in gene G 1.4e-14 IGAP 2013: Stages 1 and 2 NG00036
upstream T 1.8e-14 IGAP 2013: Stages 1 and 2 NG00036
in gene G 1.8e-14 IGAP 2013: Stages 1 and 2 NG00036
upstream C 1.9e-14 IGAP 2013: Stages 1 and 2 NG00036
in gene T 2.1e-14 IGAP 2013: Stages 1 and 2 NG00036
in gene T 2.1e-14 IGAP 2013: Stages 1 and 2 NG00036
upstream C 2.1e-14 IGAP 2013: Stages 1 and 2 NG00036
upstream T 2.5e-14 IGAP 2013: Stages 1 and 2 NG00036
in gene A 2.6e-14 IGAP 2013: Stages 1 and 2 NG00036
upstream G 3.2e-14 IGAP 2013: Stages 1 and 2 NG00036
upstream A 3.4e-14 IGAP 2013: Stages 1 and 2 NG00036
in gene C 7.0e-14 IGAP 2013: Stages 1 and 2 NG00036
upstream T 7.6e-14 IGAP 2013: Stages 1 and 2 NG00036
downstream A 7.7e-14 Transethnic LOAD: All Samples NG00056
downstream G 1.2e-13 IGAP 2013: Stages 1 and 2 NG00036
upstream T 1.3e-13 IGAP 2013: Stages 1 and 2 NG00036
downstream T 1.3e-13 IGAP 2013: Stages 1 and 2 NG00036
upstream C 1.4e-13 IGAP 2013: Stages 1 and 2 NG00036
downstream A 1.5e-13 IGAP 2013: Stages 1 and 2 NG00036
downstream A 1.6e-13 IGAP 2013: Stages 1 and 2 NG00036
downstream A 1.6e-13 IGAP 2013: Stages 1 and 2 NG00036
downstream A 1.8e-13 IGAP 2013: Stages 1 and 2 NG00036
downstream C 1.9e-13 IGAP 2013: Stages 1 and 2 NG00036
downstream T 2.0e-13 IGAP 2013: Stages 1 and 2 NG00036
downstream G 2.0e-13 IGAP 2013: Stages 1 and 2 NG00036
downstream C 2.0e-13 IGAP 2013: Stages 1 and 2 NG00036
downstream G 2.0e-13 IGAP 2013: Stages 1 and 2 NG00036
downstream C 2.0e-13 IGAP 2013: Stages 1 and 2 NG00036
downstream C 2.2e-13 IGAP 2013: Stages 1 and 2 NG00036
downstream A 2.3e-13 IGAP 2013: Stages 1 and 2 NG00036
downstream C 2.3e-13 IGAP 2013: Stages 1 and 2 NG00036
downstream A 2.4e-13 IGAP 2013: Stages 1 and 2 NG00036
downstream A 2.5e-13 IGAP 2013: Stages 1 and 2 NG00036
downstream T 2.5e-13 IGAP 2013: Stages 1 and 2 NG00036
downstream T 2.7e-13 IGAP 2013: Stages 1 and 2 NG00036
downstream C 2.7e-13 IGAP 2013: Stages 1 and 2 NG00036
downstream A 3.1e-13 IGAP 2013: Stages 1 and 2 NG00036
downstream C 3.3e-13 IGAP 2013: Stages 1 and 2 NG00036
downstream G 3.3e-13 IGAP 2013: Stages 1 and 2 NG00036
downstream G 3.4e-13 IGAP 2013: Stages 1 and 2 NG00036
downstream C 3.5e-13 IGAP 2013: Stages 1 and 2 NG00036
downstream C 3.6e-13 IGAP 2013: Stages 1 and 2 NG00036
downstream C 3.8e-13 IGAP 2013: Stages 1 and 2 NG00036
downstream C 3.9e-13 IGAP 2013: Stages 1 and 2 NG00036
upstream T 4.1e-13 IGAP 2013: Stages 1 and 2 NG00036
downstream T 4.2e-13 IGAP 2013: Stages 1 and 2 NG00036
downstream A 4.4e-13 IGAP 2013: Stages 1 and 2 NG00036
downstream C 4.5e-13 IGAP 2013: Stages 1 and 2 NG00036
downstream G 4.6e-13 IGAP 2013: Stages 1 and 2 NG00036
downstream C 4.7e-13 IGAP 2013: Stages 1 and 2 NG00036
downstream A 4.8e-13 IGAP 2013: Stages 1 and 2 NG00036
downstream G 4.9e-13 IGAP 2013: Stages 1 and 2 NG00036
downstream G 5.0e-13 IGAP 2013: Stages 1 and 2 NG00036
downstream T 5.0e-13 IGAP 2013: Stages 1 and 2 NG00036
downstream C 5.2e-13 IGAP 2013: Stages 1 and 2 NG00036
downstream A 5.3e-13 IGAP 2013: Stages 1 and 2 NG00036
upstream T 7.2e-13 IGAP 2013: Stages 1 and 2 NG00036
upstream G 7.8e-13 IGAP 2013: Stages 1 and 2 NG00036
upstream A 8.0e-13 IGAP 2013: Stages 1 and 2 NG00036
downstream T 8.9e-13 IGAP 2013: Stages 1 and 2 NG00036
downstream A 8.9e-13 IGAP 2013: Stages 1 and 2 NG00036
upstream G 1.4e-12 IGAP 2013: Stages 1 and 2 NG00036
downstream C 1.5e-12 IGAP 2013: Stages 1 and 2 NG00036
upstream C 1.6e-12 IGAP 2013: Stages 1 and 2 NG00036
upstream C 1.6e-12 IGAP 2013: Stages 1 and 2 NG00036
downstream T 1.9e-12 IGAP 2013: Stages 1 and 2 NG00036
downstream A 2.0e-12 IGAP 2013: Stage 1 NG00036
upstream C 2.2e-12 IGAP 2013: Stages 1 and 2 NG00036
upstream G 2.5e-12 IGAP 2013: Stages 1 and 2 NG00036
upstream T 2.9e-12 IGAP 2013: Stages 1 and 2 NG00036
upstream G 3.3e-12 IGAP 2013: Stages 1 and 2 NG00036
upstream G 4.0e-12 IGAP 2013: Stages 1 and 2 NG00036
downstream A 4.8e-12 IGAP 2013: Stages 1 and 2 NG00036
upstream T 5.5e-12 IGAP 2013: Stages 1 and 2 NG00036
downstream A 5.9e-12 Transethnic LOAD: All Samples NG00056
upstream G 6.1e-12 IGAP 2013: Stages 1 and 2 NG00036
in gene C 6.6e-12 IGAP 2013: Stages 1 and 2 NG00036
upstream A 7.4e-12 Transethnic LOAD: All Samples NG00056
downstream A 7.4e-12 Transethnic LOAD: All Samples NG00056
upstream G 7.7e-12 IGAP 2013: Stages 1 and 2 NG00036
downstream T 7.8e-12 IGAP 2013: Stage 1 NG00036
downstream T 7.9e-12 Transethnic LOAD: All Samples NG00056
upstream T 8.1e-12 IGAP 2013: Stages 1 and 2 NG00036
downstream T 8.2e-12 Transethnic LOAD: All Samples NG00056
in gene C 8.2e-12 IGAP 2013: Stages 1 and 2 NG00036
downstream A 8.5e-12 Transethnic LOAD: All Samples NG00056
downstream A 9.0e-12 Transethnic LOAD: All Samples NG00056
upstream C 9.5e-12 IGAP 2013: Stages 1 and 2 NG00036
downstream A 9.9e-12 Transethnic LOAD: All Samples NG00056
in gene A 1.0e-11 IGAP 2013: Stages 1 and 2 NG00036
in gene T 1.0e-11 IGAP 2013: Stages 1 and 2 NG00036
downstream A 1.0e-11 Transethnic LOAD: All Samples NG00056
upstream A 1.0e-11 IGAP 2013: Stages 1 and 2 NG00036
upstream A 1.1e-11 IGAP 2013: Stages 1 and 2 NG00036
upstream C 1.1e-11 IGAP 2013: Stages 1 and 2 NG00036
downstream G 1.1e-11 IGAP 2013: Stages 1 and 2 NG00036
upstream T 1.1e-11 IGAP 2013: Stages 1 and 2 NG00036
downstream C 1.2e-11 Transethnic LOAD: All Samples NG00056
upstream G 1.2e-11 IGAP 2013: Stages 1 and 2 NG00036
downstream A 1.2e-11 Transethnic LOAD: All Samples NG00056
upstream T 1.2e-11 IGAP 2013: Stages 1 and 2 NG00036
downstream T 1.2e-11 Transethnic LOAD: All Samples NG00056
downstream N/A T 1.2e-11 Transethnic LOAD: All Samples NG00056
downstream C 1.3e-11 Transethnic LOAD: All Samples NG00056
downstream T 1.3e-11 IGAP 2013: Stages 1 and 2 NG00036
downstream T 1.4e-11 Transethnic LOAD: All Samples NG00056
downstream A 1.4e-11 Transethnic LOAD: All Samples NG00056
downstream T 1.5e-11 Transethnic LOAD: All Samples NG00056
downstream A 1.5e-11 Transethnic LOAD: All Samples NG00056
downstream A 1.5e-11 Transethnic LOAD: All Samples NG00056
downstream A 1.5e-11 Transethnic LOAD: All Samples NG00056
downstream T 1.5e-11 Transethnic LOAD: All Samples NG00056
downstream A 1.5e-11 Transethnic LOAD: All Samples NG00056
downstream T 1.6e-11 Transethnic LOAD: All Samples NG00056
downstream T 1.6e-11 Transethnic LOAD: All Samples NG00056
downstream C 1.6e-11 Transethnic LOAD: All Samples NG00056
downstream T 1.6e-11 Transethnic LOAD: All Samples NG00056
downstream A 1.6e-11 Transethnic LOAD: All Samples NG00056
downstream A 1.6e-11 Transethnic LOAD: All Samples NG00056
downstream T 1.6e-11 Transethnic LOAD: All Samples NG00056
downstream A 1.6e-11 Transethnic LOAD: All Samples NG00056
downstream A 1.7e-11 Transethnic LOAD: All Samples NG00056
downstream A 1.7e-11 Transethnic LOAD: All Samples NG00056
downstream T 1.7e-11 IGAP 2013: Stage 1 NG00036
downstream C 1.7e-11 Transethnic LOAD: All Samples NG00056
in gene T 1.8e-11 Transethnic LOAD: All Samples NG00056
downstream T 1.8e-11 Transethnic LOAD: All Samples NG00056
downstream C 1.8e-11 Transethnic LOAD: All Samples NG00056
downstream T 1.8e-11 Transethnic LOAD: All Samples NG00056
upstream C 1.8e-11 IGAP 2013: Stages 1 and 2 NG00036
in gene C 1.8e-11 IGAP 2013: Stages 1 and 2 NG00036
downstream A 1.8e-11 Transethnic LOAD: All Samples NG00056
downstream A 1.8e-11 Transethnic LOAD: All Samples NG00056
downstream A 1.9e-11 Transethnic LOAD: All Samples NG00056
downstream T 1.9e-11 Transethnic LOAD: All Samples NG00056
downstream A 1.9e-11 Transethnic LOAD: All Samples NG00056
downstream T 1.9e-11 Transethnic LOAD: All Samples NG00056
downstream T 1.9e-11 Transethnic LOAD: All Samples NG00056
upstream T 2.0e-11 IGAP 2013: Stages 1 and 2 NG00036
downstream A 2.0e-11 Transethnic LOAD: All Samples NG00056
downstream A 2.0e-11 Transethnic LOAD: All Samples NG00056
downstream A 2.1e-11 Transethnic LOAD: All Samples NG00056
downstream C 2.1e-11 Transethnic LOAD: All Samples NG00056
downstream A 2.2e-11 Transethnic LOAD: All Samples NG00056
downstream A 2.2e-11 Transethnic LOAD: All Samples NG00056
in gene A 2.3e-11 Transethnic LOAD: All Samples NG00056
downstream T 2.3e-11 Transethnic LOAD: All Samples NG00056
downstream A 2.4e-11 Transethnic LOAD: All Samples NG00056
upstream C 2.4e-11 IGAP 2013: Stages 1 and 2 NG00036
downstream A 2.4e-11 Transethnic LOAD: All Samples NG00056
downstream T 2.5e-11 Transethnic LOAD: All Samples NG00056
downstream A 2.6e-11 Transethnic LOAD: All Samples NG00056
downstream A 2.6e-11 Transethnic LOAD: All Samples NG00056
upstream A 2.6e-11 Transethnic LOAD: All Samples NG00056
upstream G 2.8e-11 IGAP 2013: Stage 1 NG00036
downstream T 2.8e-11 Transethnic LOAD: All Samples NG00056
downstream T 3.0e-11 Transethnic LOAD: All Samples NG00056
downstream A 3.1e-11 Transethnic LOAD: All Samples NG00056
downstream G 3.3e-11 IGAP 2013: Stages 1 and 2 NG00036
downstream T 3.3e-11 Transethnic LOAD: All Samples NG00056
downstream T 3.4e-11 Transethnic LOAD: All Samples NG00056
upstream C 3.6e-11 IGAP 2013: Stage 1 NG00036
upstream N/A G 3.6e-11 IGAP 2013: Stage 1 NG00036
upstream N/A A 3.8e-11 IGAP 2013: Stage 1 NG00036
downstream T 3.9e-11 Transethnic LOAD: All Samples NG00056
downstream C 4.0e-11 IGAP 2013: Stage 1 NG00036
downstream G 4.0e-11 IGAP 2013: Stage 1 NG00036
downstream N/A T 4.1e-11 Transethnic LOAD: All Samples NG00056
downstream C 4.2e-11 IGAP 2013: Stage 1 NG00036
upstream A 4.2e-11 IGAP 2013: Stage 1 NG00036
upstream A 4.3e-11 IGAP 2013: Stage 1 NG00036
downstream G 4.3e-11 IGAP 2013: Stage 1 NG00036
downstream A 4.5e-11 IGAP (2013): ADGC Subset NG00053
downstream A 4.7e-11 Transethnic LOAD: All Samples NG00056
upstream C 4.7e-11 IGAP 2013: Stage 1 NG00036
in gene A 4.7e-11 Transethnic LOAD: All Samples NG00056
downstream A 4.9e-11 Transethnic LOAD: All Samples NG00056
upstream G 5.0e-11 IGAP 2013: Stages 1 and 2 NG00036
downstream C 5.0e-11 IGAP 2013: Stage 1 NG00036
upstream A 5.0e-11 IGAP 2013: Stage 1 NG00036
downstream A 5.1e-11 IGAP 2013: Stages 1 and 2 NG00036
downstream C 5.1e-11 IGAP 2013: Stage 1 NG00036
downstream T 5.1e-11 Transethnic LOAD: All Samples NG00056
downstream A 5.3e-11 Transethnic LOAD: All Samples NG00056
downstream T 5.4e-11 Transethnic LOAD: All Samples NG00056
downstream A 5.5e-11 Transethnic LOAD: All Samples NG00056
downstream C 5.6e-11 IGAP 2013: Stage 1 NG00036
in gene T 5.7e-11 Transethnic LOAD: All Samples NG00056
downstream T 5.9e-11 Transethnic LOAD: All Samples NG00056
downstream A 5.9e-11 ADGC 2011: Stages 1 and 2 NG00027
downstream G 6.2e-11 IGAP 2013: Stage 1 NG00036
upstream C 6.6e-11 IGAP 2013: Stage 1 NG00036
downstream T 6.6e-11 IGAP 2013: Stage 1 NG00036
upstream T 6.8e-11 Transethnic LOAD: All Samples NG00056
upstream T 7.1e-11 Transethnic LOAD: All Samples NG00056
in gene T 7.3e-11 Transethnic LOAD: All Samples NG00056
downstream A 7.4e-11 IGAP 2013: Stage 1 NG00036
downstream C 7.6e-11 IGAP 2013: Stage 1 NG00036
upstream A 8.5e-11 IGAP 2013: Stage 1 NG00036
downstream G 8.5e-11 IGAP 2013: Stages 1 and 2 NG00036
in gene C 9.0e-11 Transethnic LOAD: All Samples NG00056
downstream T 9.1e-11 Transethnic LOAD: All Samples NG00056
downstream A 1.0e-10 Transethnic LOAD: All Samples NG00056
upstream A 1.0e-10 Transethnic LOAD: All Samples NG00056
downstream C 1.0e-10 IGAP 2013: Stage 1 NG00036
upstream A 1.1e-10 Transethnic LOAD: All Samples NG00056
downstream A 1.1e-10 IGAP 2013: Stage 1 NG00036
upstream T 1.2e-10 Transethnic LOAD: All Samples NG00056
downstream A 1.2e-10 IGAP 2013: Stage 1 NG00036
downstream T 1.2e-10 IGAP 2013: Stage 1 NG00036
downstream C 1.2e-10 IGAP 2013: Stage 1 NG00036
downstream A 1.3e-10 IGAP 2013: Stage 1 NG00036
upstream T 1.3e-10 Transethnic LOAD: All Samples NG00056
upstream C 1.3e-10 IGAP 2013: Stage 1 NG00036
downstream G 1.3e-10 IGAP 2013: Stage 1 NG00036
downstream A 1.3e-10 IGAP 2013: Stage 1 NG00036
downstream T 1.3e-10 IGAP 2013: Stage 1 NG00036
downstream T 1.3e-10 IGAP 2013: Stage 1 NG00036
downstream C 1.4e-10 IGAP 2013: Stage 1 NG00036
downstream A 1.4e-10 IGAP 2013: Stage 1 NG00036
downstream A 1.4e-10 IGAP 2013: Stage 1 NG00036
upstream T 1.4e-10 IGAP 2013: Stage 1 NG00036
downstream C 1.5e-10 IGAP 2013: Stage 1 NG00036
downstream C 1.5e-10 IGAP 2013: Stages 1 and 2 NG00036
downstream G 1.5e-10 IGAP 2013: Stage 1 NG00036
downstream T 1.6e-10 IGAP 2013: Stage 1 NG00036
downstream A 1.6e-10 IGAP 2013: Stage 1 NG00036
in gene G 1.6e-10 IGAP 2013: Stage 1 NG00036
downstream A 1.7e-10 Transethnic LOAD: All Samples NG00056
downstream A 1.7e-10 IGAP 2013: Stage 1 NG00036
downstream G 1.7e-10 IGAP 2013: Stage 1 NG00036
downstream C 1.7e-10 IGAP 2013: Stage 1 NG00036
downstream C 1.7e-10 IGAP 2013: Stage 1 NG00036
downstream A 1.7e-10 IGAP 2013: Stage 1 NG00036
in gene T 1.7e-10 IGAP 2013: Stage 1 NG00036
in gene A 1.7e-10 IGAP 2013: Stage 1 NG00036
downstream C 1.8e-10 IGAP 2013: Stage 1 NG00036
downstream C 1.8e-10 IGAP 2013: Stage 1 NG00036
downstream C 1.8e-10 IGAP 2013: Stage 1 NG00036
downstream G 1.8e-10 IGAP 2013: Stage 1 NG00036
downstream C 1.8e-10 IGAP 2013: Stage 1 NG00036
downstream G 1.8e-10 IGAP 2013: Stage 1 NG00036
downstream G 1.9e-10 IGAP 2013: Stage 1 NG00036
in gene T 1.9e-10 IGAP 2013: Stage 1 NG00036
in gene G 1.9e-10 IGAP 2013: Stage 1 NG00036
downstream G 1.9e-10 IGAP 2013: Stage 1 NG00036
in gene C 1.9e-10 IGAP 2013: Stage 1 NG00036
downstream G 2.0e-10 IGAP 2013: Stage 1 NG00036
upstream C 2.0e-10 IGAP 2013: Stage 1 NG00036
upstream T 2.1e-10 IGAP 2013: Stage 1 NG00036
upstream C 2.1e-10 IGAP 2013: Stage 1 NG00036
downstream A 2.1e-10 IGAP 2013: Stage 1 NG00036
downstream T 2.2e-10 IGAP 2013: Stage 1 NG00036
downstream C 2.2e-10 IGAP 2013: Stage 1 NG00036
downstream T 2.5e-10 Transethnic LOAD: All Samples NG00056
downstream A 2.5e-10 Transethnic LOAD: All Samples NG00056
upstream C 2.6e-10 IGAP 2013: Stage 1 NG00036
upstream C 2.6e-10 Transethnic LOAD: All Samples NG00056
downstream C 2.7e-10 IGAP 2013: Stage 1 NG00036
upstream G 2.8e-10 IGAP 2013: Stage 1 NG00036
downstream N/A C 2.9e-10 IGAP 2013: Stage 1 NG00036
upstream T 3.0e-10 IGAP 2013: Stage 1 NG00036
downstream T 3.1e-10 Transethnic LOAD: All Samples NG00056
downstream A 3.1e-10 IGAP 2013: Stage 1 NG00036
upstream C 3.3e-10 IGAP 2013: Stage 1 NG00036
upstream T 3.3e-10 IGAP 2013: Stage 1 NG00036
upstream T 3.3e-10 IGAP 2013: Stage 1 NG00036
upstream T 3.3e-10 IGAP 2013: Stage 1 NG00036
downstream C 3.5e-10 IGAP 2013: Stage 1 NG00036
downstream A 3.5e-10 IGAP 2013: Stage 1 NG00036
upstream G 3.5e-10 IGAP 2013: Stage 1 NG00036
downstream T 3.5e-10 IGAP (2013): ADGC Subset NG00053
downstream G 3.6e-10 IGAP 2013: Stage 1 NG00036
downstream A 3.6e-10 IGAP 2013: Stage 1 NG00036
upstream T 3.7e-10 IGAP 2013: Stage 1 NG00036
upstream T 3.8e-10 IGAP 2013: Stage 1 NG00036
upstream A 3.8e-10 IGAP 2013: Stage 1 NG00036
downstream T 4.1e-10 IGAP 2013: Stage 1 NG00036
upstream T 4.2e-10 IGAP 2013: Stage 1 NG00036
downstream A 4.2e-10 IGAP 2013: Stage 1 NG00036
downstream A 4.2e-10 IGAP 2013: Stage 1 NG00036
upstream A 4.6e-10 Transethnic LOAD: All Samples NG00056
downstream C 4.8e-10 IGAP 2013: Stage 1 NG00036
upstream T 5.0e-10 IGAP 2013: Stage 1 NG00036
downstream T 5.1e-10 IGAP 2013: Stage 1 NG00036
in gene C 5.2e-10 IGAP 2013: Stage 1 NG00036
downstream T 5.3e-10 IGAP 2013: Stage 1 NG00036
downstream A 5.4e-10 IGAP 2013: Stage 1 NG00036
downstream A 5.5e-10 IGAP 2013: Stage 1 NG00036
upstream A 5.7e-10 Transethnic LOAD: All Samples NG00056
upstream N/A A 6.0e-10 Transethnic LOAD: All Samples NG00056
downstream A 6.0e-10 IGAP 2013: Stage 1 NG00036
upstream A 6.3e-10 IGAP 2013: Stage 1 NG00036
downstream T 6.3e-10 IGAP 2013: Stage 1 NG00036
downstream C 6.8e-10 IGAP 2013: Stage 1 NG00036
upstream C 6.9e-10 Transethnic LOAD: All Samples NG00056
upstream A 7.3e-10 IGAP (2013): ADGC Subset NG00053
downstream G 7.6e-10 IGAP 2013: Stage 1 NG00036
downstream T 7.7e-10 IGAP 2013: Stage 1 NG00036
downstream C 7.9e-10 Transethnic LOAD: All Samples NG00056
upstream A 8.4e-10 IGAP 2013: Stage 1 NG00036
downstream T 8.8e-10 IGAP 2013: Stage 1 NG00036
upstream G 8.9e-10 IGAP 2013: Stage 1 NG00036
downstream A 9.1e-10 IGAP (2013): ADGC Subset NG00053
downstream A 9.4e-10 IGAP (2013): ADGC Subset NG00053
upstream C 9.9e-10 IGAP 2013: Stage 1 NG00036
downstream A 9.9e-10 ADGC 2011: Stages 1 and 2 NG00027
in gene T 1.1e-9 Transethnic LOAD: All Samples NG00056
upstream T 1.1e-9 IGAP 2013: Stage 1 NG00036
upstream T 1.1e-9 IGAP 2013: Stage 1 NG00036
upstream A 1.2e-9 IGAP 2013: Stage 1 NG00036
upstream G 1.2e-9 IGAP 2013: Stage 1 NG00036
upstream T 1.2e-9 IGAP 2013: Stage 1 NG00036
downstream T 1.2e-9 IGAP (2013): ADGC Subset NG00053
downstream T 1.2e-9 IGAP (2013): ADGC Subset NG00053
in gene A 1.2e-9 Transethnic LOAD: All Samples NG00056
downstream C 1.3e-9 IGAP (2013): ADGC Subset NG00053
downstream T 1.3e-9 IGAP (2013): ADGC Subset NG00053
downstream A 1.3e-9 IGAP (2013): ADGC Subset NG00053
upstream T 1.3e-9 IGAP 2013: Stage 1 NG00036
downstream A 1.3e-9 IGAP (2013): ADGC Subset NG00053
downstream T 1.3e-9 IGAP (2013): ADGC Subset NG00053
upstream C 1.3e-9 IGAP 2013: Stage 1 NG00036
upstream G 1.4e-9 IGAP 2013: Stage 1 NG00036
upstream T 1.4e-9 IGAP 2013: Stage 1 NG00036
in gene T 1.4e-9 Transethnic LOAD: All Samples NG00056
downstream T 1.4e-9 IGAP (2013): ADGC Subset NG00053
downstream T 1.4e-9 Transethnic LOAD: All Samples NG00056
downstream A 1.5e-9 IGAP (2013): ADGC Subset NG00053
downstream A 1.5e-9 IGAP (2013): ADGC Subset NG00053
downstream C 1.5e-9 IGAP (2013): ADGC Subset NG00053
downstream C 1.5e-9 IGAP (2013): ADGC Subset NG00053
downstream A 1.6e-9 IGAP (2013): ADGC Subset NG00053
downstream A 1.6e-9 IGAP (2013): ADGC Subset NG00053
upstream A 1.6e-9 Transethnic LOAD: All Samples NG00056
downstream T 1.6e-9 IGAP (2013): ADGC Subset NG00053
in gene T 1.6e-9 Transethnic LOAD: All Samples NG00056
downstream A 1.6e-9 IGAP (2013): ADGC Subset NG00053
downstream A 1.6e-9 IGAP (2013): ADGC Subset NG00053
downstream A 1.6e-9 IGAP (2013): ADGC Subset NG00053
upstream A 1.6e-9 Transethnic LOAD: All Samples NG00056
downstream A 1.6e-9 IGAP (2013): ADGC Subset NG00053
downstream A 1.6e-9 IGAP (2013): ADGC Subset NG00053
downstream T 1.7e-9 ADGC 2011: Stages 1 and 2 NG00027
downstream T 1.7e-9 IGAP (2013): ADGC Subset NG00053
downstream A 1.8e-9 ADGC 2011: Stages 1 and 2 NG00027
downstream T 1.8e-9 IGAP (2013): ADGC Subset NG00053
downstream A 1.8e-9 IGAP (2013): ADGC Subset NG00053
downstream C 1.8e-9 IGAP (2013): ADGC Subset NG00053
downstream C 1.9e-9 IGAP (2013): ADGC Subset NG00053
downstream T 1.9e-9 IGAP (2013): ADGC Subset NG00053
upstream T 1.9e-9 Transethnic LOAD: All Samples NG00056
downstream A 1.9e-9 IGAP (2013): ADGC Subset NG00053
downstream A 1.9e-9 IGAP (2013): ADGC Subset NG00053
downstream T 2.0e-9 IGAP 2013: Stage 1 NG00036
downstream A 2.0e-9 ADGC 2011: Stages 1 and 2 NG00027
downstream T 2.0e-9 IGAP (2013): ADGC Subset NG00053
downstream A 2.1e-9 ADGC 2011: Stages 1 and 2 NG00027
downstream T 2.1e-9 ADGC 2011: Stages 1 and 2 NG00027
downstream T 2.1e-9 ADGC 2011: Stages 1 and 2 NG00027
downstream A 2.1e-9 ADGC 2011: Stages 1 and 2 NG00027
downstream N/A T 2.1e-9 IGAP (2013): ADGC Subset NG00053
in gene T 2.2e-9 Transethnic LOAD: All Samples NG00056
downstream A 2.2e-9 ADGC 2011: Stages 1 and 2 NG00027
downstream A 2.2e-9 ADGC 2011: Stages 1 and 2 NG00027
upstream A 2.2e-9 Transethnic LOAD: All Samples NG00056
downstream T 2.2e-9 ADGC 2011: Stages 1 and 2 NG00027
downstream T 2.2e-9 AD Age of Onset Survival (IGAP) NG00058
downstream T 2.3e-9 IGAP (2013): ADGC Subset NG00053
upstream A 2.3e-9 Transethnic LOAD: All Samples NG00056
downstream A 2.3e-9 IGAP (2013): ADGC Subset NG00053
downstream C 2.3e-9 ADGC 2011: Stages 1 and 2 NG00027
downstream T 2.3e-9 IGAP (2013): ADGC Subset NG00053
downstream C 2.3e-9 ADGC 2011: Stages 1 and 2 NG00027
downstream A 2.3e-9 IGAP (2013): ADGC Subset NG00053
downstream A 2.4e-9 IGAP (2013): ADGC Subset NG00053
downstream T 2.4e-9 ADGC 2011: Stages 1 and 2 NG00027
upstream T 2.4e-9 Transethnic LOAD: All Samples NG00056
downstream T 2.4e-9 ADGC 2011: Stages 1 and 2 NG00027
downstream T 2.4e-9 ADGC 2011: Stages 1 and 2 NG00027
downstream A 2.5e-9 IGAP (2013): ADGC Subset NG00053
downstream A 2.5e-9 ADGC 2011: Stages 1 and 2 NG00027
downstream A 2.5e-9 IGAP (2013): ADGC Subset NG00053
downstream T 2.6e-9 ADGC 2011: Stages 1 and 2 NG00027
downstream T 2.6e-9 IGAP (2013): ADGC Subset NG00053
downstream A 2.6e-9 IGAP (2013): ADGC Subset NG00053
downstream A 2.6e-9 IGAP (2013): ADGC Subset NG00053
downstream T 2.7e-9 IGAP (2013): ADGC Subset NG00053
downstream T 2.7e-9 ADGC 2011: Stages 1 and 2 NG00027
upstream T 2.7e-9 Transethnic LOAD: All Samples NG00056
downstream T 2.8e-9 AD Age of Onset Survival (IGAP) NG00058
upstream T 2.8e-9 Transethnic LOAD: All Samples NG00056
in gene A 2.9e-9 Transethnic LOAD: All Samples NG00056
downstream A 3.0e-9 IGAP (2013): ADGC Subset NG00053
downstream T 3.0e-9 AD Age of Onset Survival (IGAP) NG00058
downstream T 3.1e-9 IGAP (2013): ADGC Subset NG00053
in gene T 3.1e-9 IGAP 2013: Stage 1 NG00036
upstream N/A C 3.1e-9 IGAP 2013: Stage 1 NG00036
upstream N/A A 3.1e-9 IGAP (2013): ADGC Subset NG00053
upstream C 3.2e-9 Transethnic LOAD: All Samples NG00056
upstream A 3.2e-9 IGAP (2013): ADGC Subset NG00053
downstream A 3.3e-9 IGAP (2013): ADGC Subset NG00053
upstream T 3.3e-9 IGAP (2013): ADGC Subset NG00053
upstream N/A T 3.3e-9 IGAP (2013): ADGC Subset NG00053
in gene G 3.3e-9 IGAP 2013: Stages 1 and 2 NG00036
downstream A 3.4e-9 IGAP (2013): ADGC Subset NG00053
upstream C 3.5e-9 IGAP (2013): ADGC Subset NG00053
upstream A 3.5e-9 IGAP (2013): ADGC Subset NG00053
downstream N/A T 3.8e-9 IGAP 2013: Stages 1 and 2 NG00036
upstream T 3.8e-9 IGAP 2013: Stage 1 NG00036
upstream A 3.9e-9 IGAP (2013): ADGC Subset NG00053
in gene C 4.1e-9 ADGC 2011: Stages 1 and 2 NG00027
downstream T 4.2e-9 IGAP (2013): ADGC Subset NG00053
in gene T 4.2e-9 ADGC 2011: Stages 1 and 2 NG00027
in gene A 4.5e-9 ADGC 2011: Stages 1 and 2 NG00027
in gene A 4.5e-9 ADGC 2011: Stages 1 and 2 NG00027
upstream A 4.7e-9 Transethnic LOAD: All Samples NG00056
upstream T 4.7e-9 Transethnic LOAD: All Samples NG00056
upstream A 4.7e-9 Transethnic LOAD: All Samples NG00056
upstream A 4.8e-9 IGAP (2013): ADGC Subset NG00053
downstream A 4.8e-9 IGAP 2013: Stage 1 NG00036
downstream G 4.9e-9 IGAP 2013: Stage 1 NG00036
upstream C 4.9e-9 IGAP 2013: Stage 1 NG00036
in gene C 4.9e-9 IGAP 2013: Stage 1 NG00036
downstream T 5.0e-9 AD Age of Onset Survival (IGAP) NG00058
downstream A 5.1e-9 ADGC 2011: Adjusted Stages 1 and 2 NG00027
downstream A 5.2e-9 AD Age of Onset Survival (IGAP) NG00058
upstream C 5.3e-9 Transethnic LOAD: All Samples NG00056
upstream G 5.3e-9 IGAP 2013: Stage 1 NG00036
upstream C 5.3e-9 IGAP 2013: Stage 1 NG00036
downstream T 5.3e-9 AD Age of Onset Survival (IGAP) NG00058
downstream T 5.3e-9 AD Age of Onset Survival (IGAP) NG00058
downstream T 5.3e-9 IGAP (2013): ADGC Subset NG00053
downstream