RP11-750H9.5 - ENSG00000255197
Location: chr11:47,404,699-47,430,741 reverse strand
Gene Type: antisense
- Ensembl
- ENSG00000255197
Genomic Context
The genome browser snapshot is fully interactive. Mouse over track elements for more information. Click and drag to move tracks. Click and drag on top positional guide to zoom to a sub-region.
To add tracks, use the provided link to switch to the full genome browser view.
The genome browser snapshot is fully interactive. Mouse over track elements for more information. Click and drag to move tracks. Click and drag on top positional guide to zoom to a sub-region.
To add tracks, use the provided link to switch to the full genome browser view.
Gene-based Trait Associations
ADSP WES: Alzheimer's Disease Results from gene-level rare and functional variant aggregation tests for association to AD supported by significane of p < 0.5 / #genes.
Individual score test statistics for rare, predicted functional, and loss of function variants colocated with the gene were aggregated to compute gene level p-values.
See NIAGADS Accession NG00065 for more information.
Results from gene-level rare and functional variant aggregation tests for association to AD supported by significane of p < 0.5 / #genes.
Individual score test statistics for rare, predicted functional, and loss of function variants colocated with the gene were aggregated to compute gene level p-values.
See NIAGADS Accession NG00065 for more information.
Genetic Variation and Variant-based Trait Associations (GWAS)
Variants contained within the RP11-750H9.5 gene.
Variants contained within the RP11-750H9.5 gene.
The RP11-750H9.5 gene contains 1,314 variants records (corresponding to 1,252 unique genomic positions).
The following variants, contained within ±100kb of RP11-750H9.5, have been found to be associated with Alzheimer's disease in a GWAS study:
NIAGADS GWAS: Alzheimer's Disease
Variants contained within ±100kb of RP11-750H9.5 that have genome-wide significance in a NIAGADS Alzheimer's Disease GWAS summary statistics dataset; supported by a p-value < 5 x 10-8. For exome array studies, a cutoff of p-value < 1 x 10-3 was used.
Click on accession numbers to view a detailed report about the dataset or to request access to the data.
Variants contained within ±100kb of RP11-750H9.5 that have genome-wide significance in a NIAGADS Alzheimer's Disease GWAS summary statistics dataset; supported by a p-value < 5 x 10-8. For exome array studies, a cutoff of p-value < 1 x 10-3 was used.
Click on accession numbers to view a detailed report about the dataset or to request access to the data.
Login in to select variants and add them to your basket.
| Relative Position | Variant | ADSP? | Allele | p-Value | Track | Accession |
|---|---|---|---|---|---|---|
| upstream | N/A | 6.0e-19 | ADSP Single-Variant Risk Association: meta analysis (Model 1) | NG00065 | ||
| upstream | N/A | 6.0e-19 | ADSP Single-Variant Risk Association: Caribbean Hispanic (Model 1) | NG00065 | ||
| upstream | N/A | 6.0e-19 | ADSP Single-Variant Risk Association: European (Model 1) | NG00065 | ||
| upstream | N/A | 1.7e-15 | ADSP Single-Variant Risk Association: Caribbean Hispanic (Model 2) | NG00065 | ||
| upstream | N/A | 1.7e-15 | ADSP Single-Variant Risk Association: European (Model 2) | NG00065 | ||
| upstream | N/A | 1.7e-15 | ADSP Single-Variant Risk Association: meta analysis (Model 2) | NG00065 | ||
| upstream | N/A | 1.3e-8 | ADSP Single-Variant Risk Association: Caribbean Hispanic (Model 1) | NG00065 | ||
| upstream | N/A | 1.3e-8 | ADSP Single-Variant Risk Association: European (Model 1) | NG00065 | ||
| upstream | G | 1.4e-8 | IGAP 2013: Stages 1 and 2 | NG00036 | ||
| downstream | A | 1.9e-8 | IGAP 2013: Stages 1 and 2 | NG00036 | ||
| downstream | A | 2.4e-8 | IGAP 2013: Stages 1 and 2 | NG00036 | ||
| downstream | A | 2.9e-8 | IGAP 2013: Stages 1 and 2 | NG00036 | ||
| in gene | T | 3.0e-8 | IGAP 2013: Stages 1 and 2 | NG00036 | ||
| downstream | G | 3.0e-8 | IGAP 2013: Stages 1 and 2 | NG00036 | ||
| downstream | C | 3.2e-8 | IGAP 2013: Stages 1 and 2 | NG00036 | ||
| in gene | A | 3.5e-8 | IGAP 2013: Stages 1 and 2 | NG00036 | ||
| in gene | N/A | A | 3.6e-8 | IGAP 2013: Stages 1 and 2 | NG00036 | |
| in gene | A | 3.9e-8 | IGAP 2013: Stages 1 and 2 | NG00036 | ||
| downstream | G | 4.3e-8 | IGAP 2013: Stages 1 and 2 | NG00036 |
NHGRI GWAS: Alzheimer's Disease
Variants contained within ±100kb of RP11-750H9.5 that are associated with Alzheimer's disease in the NHGRI GWAS Catalog.
Variants contained within ±100kb of RP11-750H9.5 that are associated with Alzheimer's disease in the NHGRI GWAS Catalog.
The following variants, contained within ±100kb of RP11-750H9.5, have been associated with AD-relevant neuropathologies in a GWAS study:
NIAGADS GWAS: AD biomarkers and related neuropathologies
Variants contained within ±100kb of RP11-750H9.5 that have genome-wide significance in a NIAGADS GWAS summary statistics dataset; supported by a p-value < 5 x 10-8. For exome array studies, a cutoff of p-value < 1 x 10-3 was used.
Click on accession numbers to view a detailed report about the dataset or to request access to the data.
Variants contained within ±100kb of RP11-750H9.5 that have genome-wide significance in a NIAGADS GWAS summary statistics dataset; supported by a p-value < 5 x 10-8. For exome array studies, a cutoff of p-value < 1 x 10-3 was used.
Click on accession numbers to view a detailed report about the dataset or to request access to the data.
NHGRI GWAS: Other Traits (incl. related neuropathologies and AD biomarkers)
Variants contained within ±100kb of RP11-750H9.5 that are associated with a trait in the NHGRI GWAS Catalog.
Variants contained within ±100kb of RP11-750H9.5 that are associated with a trait in the NHGRI GWAS Catalog.
Functional Genomics
Explore all functional genomics annotations within the region of the RP11-750H9.5 gene (chr11:47404699-47430741)
Transcription Factor Binding Site Overlap in Gene Promoter Region (ENCODE ChIP-SEQ)
ChIP-Seq sites for transcription factor binding (from selected brain-relevant ENCODE tracks) within the promoter region of this gene. See methods for more information.
ChIP-Seq sites for transcription factor binding (from selected brain-relevant ENCODE tracks) within the promoter region of this gene. See methods for more information.
Functional Annotation
Gene Ontology
Functional annotations were obtained from UniProt-GOA gene association files.
Click on a term accession number to view term details at the Gene Ontology Consortium.
Functional annotations were obtained from UniProt-GOA gene association files.
Click on a term accession number to view term details at the Gene Ontology Consortium.
KEGG Pathways
Click on a pathway accession number to view term details at KEGG.
Click on the number in the Find Similar column to get a list of genes annotated by the associated pathway.
Click on a pathway accession number to view term details at KEGG.
Click on the number in the Find Similar column to get a list of genes annotated by the associated pathway.
and click each search that needs revision.