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APOE - ENSG00000130203

apolipoprotein E

Location: chr19:45409011-45412650

Gene Type: protein coding

More information
NCBI Gene
348
HUGO
HGNC:613
Ensembl
ENSG00000130203
VEGA
OTTHUMG00000128901
OMIM
107741

Genomic Context

The genome browser snapshot is fully interactive. Mouse over track elements for more information. Click and drag to move tracks. Click and drag on top positional guide to zoom to a sub-region.

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Genetic Variation

Variants contained within the APOE gene.

436 variant records (corresponding to 394 unique genomic positions) are contained within the APOE gene.

The following variants, contained within ± 100kb of the gene, were found to have genome-wide significance in a NIAGADS dataset or the NHGRI GWAS Catalog:

NIAGADS: Alzheimer's Disease

NIAGADS AD GWAS summary statistics datasets in which colocated variants have a genome-wide significance supported by a p-value ≤ 5 x 10-8.

For exome array studies, a cutoff of p-value < 1 x 10-3 was used.

Click on accession numbers to view a detailed report about the dataset or to request access to the data.

Login in to select variants and add them to your basket.

Relative Position Variant Allele p-Value Track Accession
downstream A 0.000 ADGC 2011: Stages 1 and 2 NG00027
upstream T 2.5e-575 IGAP 2013: Stage 1 NG00036
in gene C 6.7e-536 IGAP 2013: Stage 1 NG00036
in gene A 9.9e-523 IGAP 2013: Stage 1 NG00036
downstream A 1.2e-522 IGAP 2013: Stage 1 NG00036
downstream T 1.8e-520 IGAP 2013: Stage 1 NG00036
upstream T 2.0e-486 IGAP 2013: Stage 1 NG00036
downstream G 7.8e-482 IGAP 2013: Stage 1 NG00036
upstream G 8.5e-475 IGAP 2013: Stage 1 NG00036
upstream C 8.9e-469 IGAP 2013: Stage 1 NG00036
upstream G 6.4e-466 IGAP 2013: Stage 1 NG00036
upstream T 2.6e-464 IGAP 2013: Stage 1 NG00036
upstream G 5.1e-464 IGAP 2013: Stage 1 NG00036
upstream C 2.5e-462 IGAP 2013: Stage 1 NG00036
downstream A 2.0e-454 IGAP 2013: Stage 1 NG00036
upstream G 6.5e-442 IGAP 2013: Stage 1 NG00036
upstream A 4.9e-440 IGAP 2013: Stage 1 NG00036
upstream G 2.7e-434 IGAP 2013: Stage 1 NG00036
upstream G 3.2e-434 IGAP 2013: Stage 1 NG00036
upstream T 9.7e-434 IGAP 2013: Stage 1 NG00036
upstream A 5.4e-432 IGAP 2013: Stage 1 NG00036
downstream A 2.5e-427 IGAP 2013: Stage 1 NG00036
downstream A 1.1e-421 IGAP 2013: Stage 1 NG00036
downstream A 7.0e-405 IGAP 2013: Stage 1 NG00036
downstream G 1.7e-396 IGAP 2013: Stage 1 NG00036
downstream C 8.6e-390 IGAP 2013: Stage 1 NG00036
downstream T 2.1e-373 IGAP 2013: Stage 1 NG00036
upstream A 3.2e-354 IGAP 2013: Stage 1 NG00036
upstream A 1.2e-342 IGAP 2013: Stage 1 NG00036
downstream T 2.8e-326 IGAP 2013: Stage 1 NG00036
downstream A 1.1e-266 ADGC 2011: Stage 1 NG00027
upstream T 2.2e-206 ADGC 2011: Stage 1 NG00027
upstream A 6.2e-184 ADGC 2011: Stage 1 NG00027
upstream T 8.2e-178 ADGC 2011: Stage 1 NG00027
upstream G 2.2e-167 IGAP 2013: Stage 1 NG00036
downstream A 1.7e-134 IGAP 2013: Stage 1 NG00036
upstream A 1.1e-128 ADGC 2011: Stage 1 NG00027
upstream G 1.7e-128 IGAP 2013: Stage 1 NG00036
upstream C 2.3e-127 IGAP 2013: Stage 1 NG00036
upstream C 1.0e-126 IGAP 2013: Stage 1 NG00036
upstream G 1.7e-126 IGAP 2013: Stage 1 NG00036
upstream A 3.3e-125 IGAP 2013: Stage 1 NG00036
upstream T 6.2e-125 IGAP 2013: Stage 1 NG00036
downstream A 3.8e-121 ADGC 2011: Stage 2 NG00027
upstream T 3.5e-115 IGAP 2013: Stage 1 NG00036
upstream G 2.0e-114 IGAP 2013: Stage 1 NG00036
upstream T 4.8e-114 IGAP 2013: Stage 1 NG00036
upstream C 3.2e-112 IGAP 2013: Stage 1 NG00036
downstream A 9.0e-109 IGAP 2013: Stage 1 NG00036
upstream A 1.5e-108 IGAP 2013: Stage 1 NG00036
in gene A 5.1e-104 IGAP 2013: Stage 1 NG00036
upstream G 1.2e-101 IGAP 2013: Stage 1 NG00036
downstream A 3.8e-101 IGAP 2013: Stage 1 NG00036
upstream G 5.4e-97 IGAP 2013: Stage 1 NG00036
upstream T 3.3e-96 ADGC Age of Onset LOAD NG00048
upstream A 3.3e-96 IGAP 2013: Stage 1 NG00036
upstream T 1.1e-93 ADGC Age of Onset LOAD NG00048
upstream T 3.5e-93 ADGC Age of Onset LOAD NG00048
downstream T 6.9e-89 IGAP 2013: Stage 1 NG00036
in gene T 8.1e-89 ADGC Age of Onset LOAD NG00048
upstream C 9.9e-89 IGAP 2013: Stage 1 NG00036
downstream T 1.3e-88 IGAP 2013: Stage 1 NG00036
upstream C 4.2e-87 IGAP 2013: Stage 1 NG00036
upstream G 1.4e-86 IGAP 2013: Stage 1 NG00036
upstream T 1.8e-85 IGAP 2013: Stage 1 NG00036
upstream C 2.8e-85 IGAP 2013: Stage 1 NG00036
upstream A 2.9e-85 IGAP 2013: Stage 1 NG00036
downstream A 3.9e-85 IGAP 2013: Stage 1 NG00036
upstream A 3.4e-84 ADGC Age of Onset LOAD NG00048
downstream C 5.0e-84 ADGC Age of Onset LOAD NG00048
downstream G 1.1e-83 IGAP 2013: Stage 1 NG00036
downstream A 1.1e-82 IGAP 2013: Stage 1 NG00036
downstream T 1.2e-82 IGAP 2013: Stage 1 NG00036
upstream G 3.4e-82 IGAP 2013: Stage 1 NG00036
downstream T 4.3e-82 IGAP 2013: Stage 1 NG00036
downstream A 5.1e-82 ADGC Age of Onset LOAD NG00048
upstream T 4.6e-81 ADGC Age of Onset LOAD NG00048
upstream A 7.8e-81 IGAP 2013: Stage 1 NG00036
upstream C 1.1e-80 IGAP 2013: Stage 1 NG00036
downstream T 3.5e-79 IGAP 2013: Stage 1 NG00036
upstream A 8.8e-79 ADGC Age of Onset LOAD NG00048
upstream A 2.1e-76 IGAP 2013: Stage 1 NG00036
upstream C 2.8e-76 IGAP 2013: Stage 1 NG00036
upstream T 2.8e-76 IGAP 2013: Stage 1 NG00036
in gene A 2.4e-75 ADGC Age of Onset LOAD NG00048
downstream T 1.5e-74 ADGC Age of Onset LOAD NG00048
upstream A 5.8e-74 ADGC 2011: Stages 1 and 2 NG00027
upstream G 4.4e-73 IGAP 2013: Stage 1 NG00036
downstream A 4.5e-73 ADGC Age of Onset LOAD NG00048
downstream A 1.1e-72 ADGC Age of Onset LOAD NG00048
upstream T 3.9e-72 IGAP 2013: Stage 1 NG00036
upstream C 9.5e-71 ADGC Age of Onset LOAD NG00048
upstream T 4.3e-70 ADGC Age of Onset LOAD NG00048
upstream T 1.1e-69 ADGC Age of Onset LOAD NG00048
upstream T 3.0e-69 IGAP 2013: Stage 1 NG00036
downstream A 3.4e-69 ADGC Age of Onset LOAD NG00048
upstream T 3.8e-69 IGAP 2013: Stage 1 NG00036
upstream C 4.7e-69 IGAP 2013: Stage 1 NG00036
upstream A 4.7e-69 IGAP 2013: Stage 1 NG00036
upstream T 5.4e-69 IGAP 2013: Stage 1 NG00036
downstream A 6.7e-69 ADGC Age of Onset LOAD NG00048
downstream T 6.3e-68 IGAP 2013: Stage 1 NG00036
upstream T 1.2e-67 IGAP 2013: Stage 1 NG00036
upstream T 1.8e-67 IGAP 2013: Stage 1 NG00036
upstream A 2.0e-67 IGAP 2013: Stage 1 NG00036
in gene C 2.3e-67 IGAP 2013: Stage 1 NG00036
upstream A 2.8e-67 ADGC Age of Onset LOAD NG00048
upstream C 2.9e-67 ADGC 2011: Stages 1 and 2 NG00027
upstream T 3.3e-67 IGAP 2013: Stage 1 NG00036
downstream A 3.7e-67 ADGC Age of Onset LOAD NG00048
upstream T 4.8e-67 IGAP 2013: Stage 1 NG00036
upstream C 4.9e-67 IGAP 2013: Stage 1 NG00036
upstream C 5.5e-67 IGAP 2013: Stage 1 NG00036
upstream C 1.2e-66 IGAP 2013: Stage 1 NG00036
upstream C 1.5e-65 IGAP 2013: Stage 1 NG00036
upstream A 1.8e-65 IGAP 2013: Stage 1 NG00036
downstream C 2.0e-65 IGAP 2013: Stage 1 NG00036
upstream A 4.1e-65 IGAP 2013: Stage 1 NG00036
downstream A 4.1e-65 IGAP 2013: Stage 1 NG00036
upstream C 4.4e-65 IGAP 2013: Stage 1 NG00036
upstream C 1.4e-64 IGAP 2013: Stage 1 NG00036
upstream T 2.6e-64 IGAP 2013: Stage 1 NG00036
upstream C 9.3e-64 IGAP 2013: Stage 1 NG00036
downstream T 1.0e-63 ADGC Age of Onset LOAD NG00048
upstream A 2.2e-63 IGAP 2013: Stage 1 NG00036
upstream A 2.6e-63 IGAP 2013: Stage 1 NG00036
upstream C 1.1e-62 IGAP 2013: Stage 1 NG00036
downstream T 1.6e-62 ADGC Age of Onset LOAD NG00048
upstream C 2.7e-62 IGAP 2013: Stage 1 NG00036
upstream A 2.8e-62 IGAP 2013: Stage 1 NG00036
downstream T 4.6e-62 IGAP 2013: Stage 1 NG00036
upstream T 5.2e-62 ADGC Age of Onset LOAD NG00048
upstream G 7.7e-61 IGAP 2013: Stage 1 NG00036
upstream T 1.2e-60 IGAP 2013: Stage 1 NG00036
upstream C 1.6e-60 ADGC Age of Onset LOAD NG00048
upstream G 6.2e-60 IGAP 2013: Stage 1 NG00036
upstream G 4.8e-59 IGAP 2013: Stage 1 NG00036
upstream A 6.2e-59 ADGC Age of Onset LOAD NG00048
upstream A 1.7e-58 IGAP 2013: Stage 1 NG00036
upstream C 4.8e-58 IGAP 2013: Stage 1 NG00036
downstream T 3.1e-56 ADGC Age of Onset LOAD NG00048
upstream A 7.3e-56 ADGC Age of Onset LOAD NG00048
upstream A 1.4e-54 ADGC 2011: Stage 1 NG00027
upstream A 2.0e-53 ADGC Age of Onset LOAD NG00048
upstream A 5.4e-53 IGAP 2013: Stage 1 NG00036
upstream A 5.5e-53 IGAP 2013: Stage 1 NG00036
upstream C 1.7e-52 IGAP 2013: Stage 1 NG00036
upstream T 3.9e-52 IGAP 2013: Stage 1 NG00036
upstream G 5.5e-52 IGAP 2013: Stage 1 NG00036
upstream A 2.3e-50 IGAP 2013: Stage 1 NG00036
upstream A 2.5e-50 ADGC 2011: Stage 1 NG00027
upstream A 5.5e-48 ADGC Age of Onset LOAD NG00048
upstream C 2.7e-47 ADGC 2011: Stages 1 and 2 NG00027
upstream T 3.9e-47 ADGC 2011: Stages 1 and 2 NG00027
upstream C 5.0e-47 ADGC 2011: Stage 1 NG00027
in gene T 5.5e-47 ADGC African Americans 2013 NG00039
upstream T 8.3e-47 IGAP 2013: Stage 1 NG00036
upstream T 1.3e-45 IGAP 2013: Stage 1 NG00036
upstream G 1.8e-45 IGAP 2013: Stage 1 NG00036
upstream A 5.1e-45 ADGC 2011: Stage 1 NG00027
downstream T 5.6e-45 ADGC 2011: Stage 1 NG00027
upstream A 1.4e-44 IGAP 2013: Stage 1 NG00036
upstream T 3.0e-44 ADGC 2011: Stage 1 NG00027
upstream T 8.7e-44 ADGC 2011: Stages 1 and 2 NG00027
downstream T 2.3e-40 IGAP 2013: Stage 1 NG00036
upstream T 2.9e-40 IGAP 2013: Stage 1 NG00036
downstream A 3.4e-40 IGAP 2013: Stage 1 NG00036
upstream T 1.5e-39 IGAP 2013: Stage 1 NG00036
upstream G 2.2e-39 IGAP 2013: Stage 1 NG00036
upstream T 3.7e-36 IGAP 2013: Stage 1 NG00036
upstream A 5.3e-36 IGAP 2013: Stage 1 NG00036
upstream T 1.2e-34 IGAP 2013: Stage 1 NG00036
upstream A 1.4e-33 IGAP 2013: Stage 1 NG00036
upstream C 1.6e-33 ADGC 2011: Stage 1 NG00027
upstream T 1.8e-33 ADGC 2011: Stage 1 NG00027
upstream T 5.5e-33 IGAP 2013: Stage 1 NG00036
upstream C 2.4e-32 ADGC 2011: Stage 1 NG00027
upstream C 4.7e-32 IGAP 2013: Stage 1 NG00036
upstream A 1.3e-31 IGAP 2013: Stage 1 NG00036
upstream T 9.3e-31 IGAP 2013: Stage 1 NG00036
upstream A 1.3e-30 IGAP 2013: Stage 1 NG00036
upstream A 1.4e-30 ADGC Age of Onset LOAD NG00048
upstream T 1.5e-30 IGAP 2013: Stage 1 NG00036
upstream G 1.7e-30 IGAP 2013: Stage 1 NG00036
downstream C 1.8e-30 IGAP 2013: Stage 1 NG00036
upstream T 2.3e-30 IGAP 2013: Stage 1 NG00036
upstream C 2.9e-30 IGAP 2013: Stage 1 NG00036
upstream T 4.2e-30 ADGC 2011: Stage 1 NG00027
downstream A 6.1e-30 ADGC Age of Onset LOAD NG00048
upstream A 1.2e-29 IGAP 2013: Stage 1 NG00036
upstream T 4.5e-29 IGAP 2013: Stage 1 NG00036
upstream G 1.1e-28 IGAP 2013: Stage 1 NG00036
upstream G 1.5e-28 IGAP 2013: Stage 1 NG00036
upstream T 1.9e-28 ADGC 2011: Stages 1 and 2 NG00027
upstream C 4.6e-28 IGAP 2013: Stage 1 NG00036
upstream A 7.5e-28 ADGC 2011: Stage 1 NG00027
upstream G 9.1e-28 IGAP 2013: Stage 1 NG00036
upstream A 3.0e-27 ADGC African Americans 2013 NG00039
upstream C 5.1e-27 IGAP 2013: Stage 1 NG00036
upstream A 1.2e-26 ADGC 2011: Stage 2 NG00027
downstream T 5.0e-26 ADGC Age of Onset LOAD NG00048
downstream A 7.1e-26 ADGC Age of Onset LOAD NG00048
upstream T 1.6e-24 IGAP 2013: Stage 1 NG00036
downstream A 2.5e-24 ADGC Age of Onset LOAD NG00048
upstream G 3.5e-24 IGAP 2013: Stage 1 NG00036
upstream A 7.0e-24 ADGC 2011: Stages 1 and 2 NG00027
upstream G 7.1e-24 IGAP 2013: Stage 1 NG00036
upstream A 1.3e-23 ADGC African Americans 2013 NG00039
upstream T 1.5e-23 IGAP 2013: Stage 1 NG00036
upstream C 2.0e-23 ADGC 2011: Stage 2 NG00027
upstream C 5.8e-23 IGAP 2013: Stage 1 NG00036
downstream A 9.7e-23 IGAP 2013: Stage 1 NG00036
in gene T 1.2e-22 IGAP 2013: Stage 1 NG00036
upstream T 2.1e-22 ADGC African Americans 2013 NG00039
upstream T 2.3e-22 ADGC African Americans 2013 NG00039
upstream A 2.6e-22 ADGC African Americans 2013 NG00039
upstream G 2.7e-22 IGAP 2013: Stage 1 NG00036
upstream T 2.8e-22 ADGC African Americans 2013 NG00039
in gene C 3.6e-22 ADGC Age of Onset LOAD NG00048
upstream C 4.7e-22 ADGC African Americans 2013 NG00039
upstream T 2.0e-21 IGAP 2013: Stage 1 NG00036
downstream A 2.1e-21 ADGC Age of Onset LOAD NG00048
downstream A 2.8e-21 IGAP 2013: Stage 1 NG00036
upstream T 8.2e-21 ADGC 2011: Stage 1 NG00027
downstream A 9.0e-21 ADGC African Americans 2013 NG00039
downstream A 1.2e-20 ADGC Age of Onset LOAD NG00048
upstream C 2.7e-20 IGAP 2013: Stage 1 NG00036
downstream T 3.6e-20 ADGC African Americans 2013 NG00039
downstream A 3.7e-20 ADGC African Americans 2013 NG00039
upstream T 4.9e-20 ADGC African Americans 2013 NG00039
upstream T 8.2e-20 ADGC African Americans 2013 NG00039
upstream C 8.4e-20 ADGC Age of Onset LOAD NG00048
upstream A 8.7e-20 ADGC African Americans 2013 NG00039
upstream G 9.6e-20 IGAP 2013: Stage 1 NG00036
upstream A 1.0e-19 IGAP 2013: Stage 1 NG00036
upstream C 1.3e-19 IGAP 2013: Stage 1 NG00036
upstream A 1.4e-19 ADGC Age of Onset LOAD NG00048
upstream T 1.6e-19 ADGC African Americans 2013 NG00039
upstream T 1.9e-19 ADGC African Americans 2013 NG00039
downstream T 2.0e-19 ADGC Age of Onset LOAD NG00048
upstream A 2.0e-19 ADGC Age of Onset LOAD NG00048
upstream T 2.1e-19 ADGC Age of Onset LOAD NG00048
upstream G 2.3e-19 IGAP 2013: Stage 1 NG00036
upstream T 2.4e-19 ADGC Age of Onset LOAD NG00048
upstream T 2.7e-19 ADGC African Americans 2013 NG00039
upstream T 3.4e-19 ADGC 2011: Stages 1 and 2 NG00027
upstream T 3.5e-19 ADGC African Americans 2013 NG00039
upstream T 3.8e-19 ADGC Age of Onset LOAD NG00048
upstream A 3.9e-19 ADGC 2011: Stages 1 and 2 NG00027
upstream T 4.9e-19 ADGC 2011: Stages 1 and 2 NG00027
upstream C 5.5e-19 ADGC Age of Onset LOAD NG00048
upstream T 5.9e-19 ADGC Age of Onset LOAD NG00048
upstream T 6.1e-19 IGAP 2013: Stage 1 NG00036
upstream C 7.5e-19 IGAP 2013: Stage 1 NG00036
upstream T 7.8e-19 ADGC Age of Onset LOAD NG00048
upstream A 8.2e-19 IGAP 2013: Stage 1 NG00036
upstream C 1.0e-18 IGAP 2013: Stage 1 NG00036
upstream G 1.0e-18 IGAP 2013: Stage 1 NG00036
upstream A 1.1e-18 IGAP 2013: Stage 1 NG00036
upstream G 1.3e-18 IGAP 2013: Stage 1 NG00036
upstream A 1.3e-18 IGAP 2013: Stage 1 NG00036
upstream A 1.6e-18 ADGC Age of Onset LOAD NG00048
downstream T 2.1e-18 IGAP 2013: Stage 1 NG00036
upstream A 2.1e-18 IGAP 2013: Stage 1 NG00036
upstream A 2.1e-18 IGAP 2013: Stage 1 NG00036
upstream G 2.2e-18 IGAP 2013: Stage 1 NG00036
downstream A 2.3e-18 ADGC African Americans 2013 NG00039
upstream A 2.4e-18 IGAP 2013: Stage 1 NG00036
downstream C 2.4e-18 IGAP 2013: Stage 1 NG00036
upstream A 2.5e-18 IGAP 2013: Stage 1 NG00036
downstream T 2.5e-18 IGAP 2013: Stage 1 NG00036
upstream G 2.6e-18 IGAP 2013: Stage 1 NG00036
upstream G 2.6e-18 IGAP 2013: Stage 1 NG00036
upstream T 3.0e-18 IGAP 2013: Stage 1 NG00036
downstream A 3.3e-18 IGAP 2013: Stage 1 NG00036
upstream C 4.3e-18 IGAP 2013: Stage 1 NG00036
upstream A 5.1e-18 IGAP 2013: Stage 1 NG00036
upstream T 5.1e-18 IGAP 2013: Stage 1 NG00036
upstream A 5.8e-18 IGAP 2013: Stage 1 NG00036
upstream T 5.9e-18 IGAP 2013: Stage 1 NG00036
upstream C 5.9e-18 IGAP 2013: Stage 1 NG00036
upstream A 6.0e-18 ADGC Age of Onset LOAD NG00048
downstream T 6.0e-18 ADGC Age of Onset LOAD NG00048
upstream C 6.6e-18 IGAP 2013: Stage 1 NG00036
upstream A 8.2e-18 IGAP 2013: Stage 1 NG00036
upstream A 8.8e-18 IGAP 2013: Stage 1 NG00036
upstream A 9.5e-18 IGAP 2013: Stage 1 NG00036
downstream G 9.6e-18 IGAP 2013: Stage 1 NG00036
upstream A 1.1e-17 IGAP 2013: Stage 1 NG00036
upstream T 1.2e-17 ADGC African Americans 2013 NG00039
upstream A 1.3e-17 ADGC 2011: Stages 1 and 2 NG00027
downstream G 1.4e-17 IGAP 2013: Stage 1 NG00036
in gene A 2.0e-17 ADGC Age of Onset LOAD NG00048
upstream C 2.0e-17 IGAP 2013: Stage 1 NG00036
upstream T 2.1e-17 IGAP 2013: Stage 1 NG00036
upstream T 2.5e-17 IGAP 2013: Stage 1 NG00036
upstream T 3.0e-17 IGAP 2013: Stage 1 NG00036
upstream C 3.2e-17 ADGC Age of Onset LOAD NG00048
upstream T 6.7e-17 ADGC Age of Onset LOAD NG00048
downstream T 7.6e-17 IGAP 2013: Stage 1 NG00036
upstream T 9.6e-17 IGAP 2013: Stage 1 NG00036
upstream A 1.3e-16 ADGC Age of Onset LOAD NG00048
upstream A 1.6e-16 ADGC African Americans 2013 NG00039
upstream T 2.0e-16 ADGC 2011: Stages 1 and 2 NG00027
upstream T 2.3e-16 IGAP 2013: Stage 1 NG00036
upstream T 2.5e-16 ADGC 2011: Stage 2 NG00027
upstream A 2.8e-16 IGAP 2013: Stage 1 NG00036
upstream C 2.9e-16 ADGC 2011: Stage 2 NG00027
downstream G 2.9e-16 IGAP 2013: Stage 1 NG00036
upstream T 3.0e-16 ADGC 2011: Stage 2 NG00027
upstream G 3.3e-16 IGAP 2013: Stage 1 NG00036
downstream G 3.4e-16 IGAP 2013: Stage 1 NG00036
upstream A 3.5e-16 IGAP 2013: Stage 1 NG00036
upstream C 3.5e-16 IGAP 2013: Stage 1 NG00036
upstream A 4.1e-16 ADGC African Americans 2013 NG00039
downstream A 4.7e-16 IGAP 2013: Stage 1 NG00036
downstream T 5.0e-16 IGAP 2013: Stage 1 NG00036
upstream A 6.3e-16 ADGC 2011: Stage 1 NG00027
downstream T 7.1e-16 ADGC Age of Onset LOAD NG00048
downstream A 7.4e-16 IGAP 2013: Stage 1 NG00036
downstream C 8.2e-16 IGAP 2013: Stage 1 NG00036
downstream C 9.8e-16 IGAP 2013: Stage 1 NG00036
upstream A 9.9e-16 ADGC 2011: Stages 1 and 2 NG00027
upstream A 1.2e-15 ADGC African Americans 2013 NG00039
downstream C 1.4e-15 IGAP 2013: Stage 1 NG00036
upstream A 1.7e-15 ADGC Age of Onset LOAD NG00048
downstream G 1.8e-15 IGAP 2013: Stage 1 NG00036
upstream A 1.8e-15 ADGC African Americans 2013 NG00039
downstream T 2.1e-15 ADGC Age of Onset LOAD NG00048
upstream C 2.2e-15 ADGC Age of Onset LOAD NG00048
downstream G 2.3e-15 IGAP 2013: Stage 1 NG00036
upstream A 3.0e-15 IGAP 2013: Stage 1 NG00036
downstream C 3.4e-15 ADGC African Americans 2013 NG00039
downstream T 4.5e-15 IGAP 2013: Stage 1 NG00036
upstream A 5.2e-15 IGAP 2013: Stage 1 NG00036
upstream G 5.4e-15 IGAP 2013: Stage 1 NG00036
upstream C 6.0e-15 IGAP 2013: Stage 1 NG00036
upstream A 6.7e-15 IGAP 2013: Stage 1 NG00036
upstream A 6.9e-15 ADGC Age of Onset LOAD NG00048
upstream T 8.5e-15 ADGC 2011: Stages 1 and 2 NG00027
upstream A 9.9e-15 IGAP 2013: Stage 1 NG00036
upstream A 1.1e-14 ADGC 2011: Stages 1 and 2 NG00027
downstream A 1.1e-14 ADGC Age of Onset LOAD NG00048
upstream T 1.1e-14 ADGC African Americans 2013 NG00039
upstream T 1.2e-14 ADGC African Americans 2013 NG00039
upstream A 1.6e-14 IGAP 2013: Stage 1 NG00036
upstream A 1.8e-14 ADGC 2011: Stage 1 NG00027
upstream A 1.9e-14 ADGC 2011: Stage 1 NG00027
upstream C 2.1e-14 IGAP 2013: Stage 1 NG00036
downstream C 2.4e-14 ADGC Age of Onset LOAD NG00048
upstream G 2.5e-14 IGAP 2013: Stage 1 NG00036
downstream T 2.6e-14 IGAP 2013: Stage 1 NG00036
upstream A 3.4e-14 ADGC 2011: Stages 1 and 2 NG00027
upstream T 3.5e-14 ADGC 2011: Stage 1 NG00027
upstream T 4.5e-14 ADGC 2011: Stage 1 NG00027
upstream T 5.4e-14 IGAP 2013: Stage 1 NG00036
upstream A 5.5e-14 ADGC 2011: Stages 1 and 2 NG00027
upstream A 5.8e-14 ADGC African Americans 2013 NG00039
upstream T 6.5e-14 ADGC 2011: Stages 1 and 2 NG00027
upstream C 7.3e-14 IGAP 2013: Stage 1 NG00036
downstream T 1.1e-13 ADGC Age of Onset LOAD NG00048
upstream C 1.2e-13 IGAP 2013: Stage 1 NG00036
upstream A 1.3e-13 IGAP 2013: Stage 1 NG00036
upstream T 1.5e-13 IGAP 2013: Stage 1 NG00036
upstream G 1.9e-13 IGAP 2013: Stage 1 NG00036
upstream A 2.0e-13 ADGC Age of Onset LOAD NG00048
upstream T 2.2e-13 IGAP 2013: Stage 1 NG00036
downstream G 2.3e-13 IGAP 2013: Stage 1 NG00036
upstream A 2.8e-13 ADGC African Americans 2013 NG00039
upstream C 3.4e-13 IGAP 2013: Stage 1 NG00036
downstream T 3.4e-13 ADGC African Americans 2013 NG00039
upstream A 4.8e-13 IGAP 2013: Stage 1 NG00036
upstream A 7.4e-13 ADGC 2011: Stage 1 NG00027
upstream A 8.8e-13 IGAP 2013: Stage 1 NG00036
downstream C 1.1e-12 IGAP 2013: Stage 1 NG00036
downstream G 1.5e-12 IGAP 2013: Stage 1 NG00036
downstream C 1.6e-12 IGAP 2013: Stage 1 NG00036
downstream A 1.8e-12 IGAP 2013: Stage 1 NG00036
upstream T 2.0e-12 IGAP 2013: Stage 1 NG00036
downstream G 2.3e-12 IGAP 2013: Stage 1 NG00036
downstream G 2.8e-12 IGAP 2013: Stage 1 NG00036
downstream C 2.8e-12 IGAP 2013: Stage 1 NG00036
downstream G 3.0e-12 IGAP 2013: Stage 1 NG00036
in gene A 3.1e-12 ADGC African Americans 2013 NG00039
downstream A 3.2e-12 ADGC African Americans 2013 NG00039
upstream G 3.6e-12 IGAP 2013: Stage 1 NG00036
upstream C 4.4e-12 IGAP 2013: Stage 1 NG00036
downstream A 4.6e-12 ADGC African Americans 2013 NG00039
upstream C 4.6e-12 IGAP 2013: Stage 1 NG00036
downstream C 4.8e-12 IGAP 2013: Stage 1 NG00036
upstream T 5.4e-12 IGAP 2013: Stage 1 NG00036
downstream T 5.5e-12 ADGC African Americans 2013 NG00039
upstream T 6.1e-12 ADGC African Americans 2013 NG00039
downstream A 6.8e-12 IGAP 2013: Stage 1 NG00036
downstream T 6.8e-12 ADGC African Americans 2013 NG00039
downstream C 7.3e-12 ADGC African Americans 2013 NG00039
upstream A 8.2e-12 IGAP 2013: Stage 1 NG00036
upstream A 8.8e-12 ADGC 2011: Stage 1 NG00027
upstream T 9.3e-12 IGAP 2013: Stage 1 NG00036
downstream A 9.6e-12 ADGC African Americans 2013 NG00039
upstream A 1.0e-11 ADGC 2011: Stage 2 NG00027
upstream T 1.0e-11 ADGC 2011: Stage 1 NG00027
upstream A 1.2e-11 ADGC Age of Onset LOAD NG00048
downstream T 1.3e-11 IGAP 2013: Stage 1 NG00036
downstream C 1.3e-11 IGAP 2013: Stage 1 NG00036
upstream C 1.4e-11 ADGC African Americans 2013 NG00039
downstream G 1.4e-11 IGAP 2013: Stage 1 NG00036
upstream C 1.5e-11 IGAP 2013: Stage 1 NG00036
downstream T 1.5e-11 IGAP 2013: Stage 1 NG00036
downstream A 1.5e-11 ADGC 2011: Adjusted Stage 1 NG00027
upstream T 1.5e-11 IGAP 2013: Stage 1 NG00036
downstream T 1.6e-11 IGAP 2013: Stage 1 NG00036
downstream G 1.6e-11 IGAP 2013: Stage 1 NG00036
downstream T 1.8e-11 IGAP 2013: Stage 1 NG00036
downstream T 1.8e-11 IGAP 2013: Stage 1 NG00036
downstream G 2.2e-11 IGAP 2013: Stage 1 NG00036
downstream A 2.2e-11 IGAP 2013: Stage 1 NG00036
downstream G 2.3e-11 IGAP 2013: Stage 1 NG00036
downstream A 2.3e-11 IGAP 2013: Stage 1 NG00036
downstream A 2.3e-11 IGAP 2013: Stage 1 NG00036
downstream T 2.4e-11 ADGC African Americans 2013 NG00039
downstream G 2.6e-11 IGAP 2013: Stage 1 NG00036
upstream T 2.9e-11 ADGC 2011: Stage 1 NG00027
downstream T 3.1e-11 IGAP 2013: Stage 1 NG00036
downstream T 3.4e-11 IGAP 2013: Stage 1 NG00036
downstream T 3.4e-11 IGAP 2013: Stage 1 NG00036
downstream T 3.6e-11 IGAP 2013: Stage 1 NG00036
downstream A 3.6e-11 IGAP 2013: Stage 1 NG00036
downstream G 3.8e-11 IGAP 2013: Stage 1 NG00036
downstream C 3.9e-11 IGAP 2013: Stage 1 NG00036
downstream G 4.0e-11 IGAP 2013: Stage 1 NG00036
downstream G 4.0e-11 IGAP 2013: Stage 1 NG00036
upstream C 4.0e-11 IGAP 2013: Stage 1 NG00036
downstream G 4.1e-11 IGAP 2013: Stage 1 NG00036
downstream A 4.1e-11 IGAP 2013: Stage 1 NG00036
downstream A 4.3e-11 IGAP 2013: Stage 1 NG00036
downstream A 4.3e-11 IGAP 2013: Stage 1 NG00036
downstream C 4.3e-11 IGAP 2013: Stage 1 NG00036
downstream G 4.3e-11 IGAP 2013: Stage 1 NG00036
downstream T 4.3e-11 IGAP 2013: Stage 1 NG00036
downstream C 4.4e-11 IGAP 2013: Stage 1 NG00036
downstream C 4.6e-11 IGAP 2013: Stage 1 NG00036
in gene A 4.9e-11 ADGC African Americans 2013 NG00039
downstream A 4.9e-11 IGAP 2013: Stage 1 NG00036
upstream C 5.1e-11 IGAP 2013: Stage 1 NG00036
downstream T 5.4e-11 IGAP 2013: Stage 1 NG00036
downstream C 5.5e-11 IGAP 2013: Stage 1 NG00036
downstream A 5.6e-11 IGAP 2013: Stage 1 NG00036
downstream A 5.7e-11 IGAP 2013: Stage 1 NG00036
upstream A 6.2e-11 ADGC 2011: Stages 1 and 2 NG00027
downstream A 6.5e-11 ADGC African Americans 2013 NG00039
downstream A 6.8e-11 IGAP 2013: Stage 1 NG00036
upstream C 7.1e-11 IGAP 2013: Stage 1 NG00036
downstream G 9.2e-11 IGAP 2013: Stage 1 NG00036
downstream T 9.5e-11 ADGC African Americans 2013 NG00039
upstream T 9.9e-11 IGAP 2013: Stage 1 NG00036
downstream C 1.1e-10 IGAP 2013: Stage 1 NG00036
downstream A 1.2e-10 ADGC African Americans 2013 NG00039
upstream T 1.3e-10 ADGC 2011: Stages 1 and 2 NG00027
upstream A 1.3e-10 IGAP 2013: Stage 1 NG00036
upstream A 1.4e-10 IGAP 2013: Stage 1 NG00036
downstream C 1.5e-10 IGAP 2013: Stage 1 NG00036
downstream G 1.7e-10 IGAP 2013: Stage 1 NG00036
downstream T 1.7e-10 IGAP 2013: Stage 1 NG00036
downstream T 1.8e-10 IGAP 2013: Stage 1 NG00036
upstream T 1.8e-10 IGAP 2013: Stage 1 NG00036
upstream A 1.8e-10 ADGC Age of Onset LOAD NG00048
downstream A 1.8e-10 IGAP 2013: Stage 1 NG00036
downstream C 2.2e-10 IGAP 2013: Stage 1 NG00036
downstream C 2.2e-10 IGAP 2013: Stage 1 NG00036
upstream T 2.4e-10 ADGC Age of Onset LOAD NG00048
downstream A 2.5e-10 IGAP 2013: Stage 1 NG00036
upstream C 2.6e-10 IGAP 2013: Stage 1 NG00036
downstream G 2.7e-10 IGAP 2013: Stage 1 NG00036
downstream C 2.8e-10 IGAP 2013: Stage 1 NG00036
downstream A 2.8e-10 IGAP 2013: Stage 1 NG00036
upstream A 3.0e-10 ADGC Age of Onset LOAD NG00048
upstream T 3.0e-10 ADGC African Americans 2013 NG00039
downstream C 3.0e-10 IGAP 2013: Stage 1 NG00036
downstream A 3.1e-10 ADGC African Americans 2013 NG00039
downstream A 3.4e-10 IGAP 2013: Stage 1 NG00036
upstream T 3.6e-10 IGAP 2013: Stage 1 NG00036
upstream T 3.7e-10 ADGC Age of Onset LOAD NG00048
downstream C 3.8e-10 IGAP 2013: Stage 1 NG00036
downstream C 3.8e-10 IGAP 2013: Stage 1 NG00036
downstream T 3.8e-10 IGAP 2013: Stage 1 NG00036
upstream T 3.9e-10 ADGC African Americans 2013 NG00039
downstream A 4.2e-10 IGAP 2013: Stage 1 NG00036
downstream A 4.4e-10 IGAP 2013: Stage 1 NG00036
downstream C 4.8e-10 IGAP 2013: Stage 1 NG00036
upstream C 4.9e-10 IGAP 2013: Stage 1 NG00036
downstream A 5.5e-10 ADGC 2011: Adjusted Stage 1 NG00027
downstream T 5.5e-10 ADGC African Americans 2013 NG00039
downstream A 5.6e-10 IGAP 2013: Stage 1 NG00036
downstream T 5.7e-10 IGAP 2013: Stage 1 NG00036
downstream C 5.7e-10 IGAP 2013: Stage 1 NG00036
downstream T 6.4e-10 IGAP 2013: Stage 1 NG00036
downstream A 6.6e-10 ADGC 2011: Adjusted Stages 1 and 2 NG00027
upstream A 6.7e-10 ADGC 2011: Stage 1 NG00027
upstream T 7.7e-10 ADGC 2011: Stage 1 NG00027
upstream T 8.3e-10 ADGC Age of Onset LOAD NG00048
downstream A 8.5e-10 ADGC 2011: Stages 1 and 2 NG00027
upstream A 8.6e-10 ADGC Age of Onset LOAD NG00048
downstream A 9.5e-10 IGAP 2013: Stage 1 NG00036
upstream A 1.0e-9 ADGC 2011: Stage 1 NG00027
downstream T 1.1e-9 ADGC African Americans 2013 NG00039
upstream T 1.1e-9 ADGC 2011: Stage 2 NG00027
upstream T 1.1e-9 IGAP 2013: Stage 1 NG00036
upstream A 1.2e-9 IGAP 2013: Stage 1 NG00036
downstream C 1.3e-9 IGAP 2013: Stage 1 NG00036
upstream A 1.7e-9 ADGC Age of Onset LOAD NG00048
upstream T 1.8e-9 ADGC African Americans 2013 NG00039
upstream A 2.4e-9 ADGC 2011: Adjusted Stage 1 NG00027
downstream C 2.6e-9 IGAP 2013: Stage 1 NG00036
upstream A 2.6e-9 IGAP 2013: Stage 1 NG00036
downstream G 2.7e-9 IGAP 2013: Stage 1 NG00036
downstream A 3.6e-9 ADGC African Americans 2013 NG00039
downstream A 3.7e-9 ADGC African Americans 2013 NG00039
downstream G 5.0e-9 IGAP 2013: Stage 1 NG00036
upstream G 5.0e-9 IGAP 2013: Stage 1 NG00036
upstream T 5.1e-9 ADGC African Americans 2013 NG00039
upstream T 5.2e-9 ADGC African Americans 2013 NG00039
upstream T 5.6e-9 ADGC Age of Onset LOAD NG00048
upstream T 5.7e-9 IGAP 2013: Stage 1 NG00036
downstream T 6.8e-9 ADGC African Americans 2013 NG00039
upstream A 7.0e-9 ADGC African Americans 2013 NG00039
upstream A 7.5e-9 IGAP 2013: Stage 1 NG00036
downstream T 7.8e-9 IGAP 2013: Stage 1 NG00036
downstream T 8.2e-9 IGAP 2013: Stage 1 NG00036
upstream T 8.6e-9 ADGC 2011: Stages 1 and 2 NG00027
downstream G 9.1e-9 IGAP 2013: Stage 1 NG00036
downstream T 9.1e-9 IGAP 2013: Stage 1 NG00036
downstream A 1.0e-8 IGAP 2013: Stage 1 NG00036
upstream A 1.0e-8 ADGC Age of Onset LOAD NG00048
upstream T 1.1e-8 IGAP 2013: Stage 1 NG00036
downstream T 1.1e-8 IGAP 2013: Stage 1 NG00036
upstream A 1.2e-8 ADGC African Americans 2013 NG00039
downstream A 1.3e-8 ADGC African Americans 2013 NG00039
downstream A 1.3e-8 IGAP 2013: Stage 1 NG00036
in gene T 1.3e-8 ADGC African Americans 2013 NG00039
downstream T 1.4e-8 IGAP 2013: Stage 1 NG00036
downstream G 1.4e-8 IGAP 2013: Stage 1 NG00036
downstream T 1.4e-8 IGAP 2013: Stage 1 NG00036
upstream T 1.5e-8 ADGC 2011: Adjusted Stage 1 NG00027
upstream T 1.5e-8 ADGC African Americans 2013 NG00039
upstream