APOE

apolipoprotein E

Also known as: AD2, LDLCQ5, LPG, APO-E

Genomic Context

The genome browser snapshot is fully interactive. Mouse over track elements for more information. Click and drag to move tracks. Click and drag on top positional guide to zoom to a sub-region.

To add tracks, use the provided link to switch to the full genome browser view.

chr19, (45409039..45412650)

Full Browser View

Variant Effect Impact (snpEff)

  • High
  • Moderate
  • Low
  • Modifier
  • Not Reported

Functional Genomics within Gene Promoter Region

ChIP-Seq TFBS from ENCODE

ChIP-Seq sites for transcription factor binding (from selected brain-relevant ENCODE tracks) within the promoter region of this gene. See methods for more information.

To view functional genomics annotations on the genome browser, first select tracks in the table below and then use the provided button to load the tracks on the browser.

Hits Track Platform Cell Type Tissue Antibody Target Functional Genomics
1
CTCF TFBS ChIP-seq on human BE2-C
ChIP-seq neuroblastoma N/A CTCF transcription factor binding site
1
CTCF TFBS ChIP-seq on human Gliobla
ChIP-seq glioblastoma cell N/A CTCF transcription factor binding site
1
CTCF TFBS ChIP-seq on human HA-sp
ChIP-seq astrocyte spinal cord CTCF transcription factor binding site
1
CTCF TFBS ChIP-seq on human HBMEC
ChIP-seq brain microvascular endothelial cell N/A CTCF transcription factor binding site
1
CTCF TFBS ChIP-seq on human SK-N-SH_RA
ChIP-seq neuroblastoma N/A CTCF transcription factor binding site
1
CTCF TFBS ChIP-seq on human SK-N-SH_RA
ChIP-seq neuroblastoma N/A CTCF transcription factor binding site
1
POLR2A TFBS ChIP-seq on human SK-N-MC
ChIP-seq neuroblastoma N/A POLR2A, POLR2 transcription factor binding site
1
POLR2A TFBS ChIP-seq on human U87
ChIP-seq glioblastoma cell N/A POLR2, POLR2A transcription factor binding site
1
USF1 TFBS ChIP-seq on human SK-N-SH_RA
ChIP-seq neuroblastoma N/A USF, USF1 transcription factor binding site

SNPs within Expressed Enhancers Sites from FANTOM5

SNPs associated with FANTOM5 identified expressed enhancers proximal to the transcription start site of this gene (tissue independent). See methods for more information.