NG00017 Data dictionary

The file Kramer.csv contains phenotype information. 
For all the columns NA means information not available.

First column ("ID") match the "ID" in the genotype file.

The second column ("SEX") notes the sex 1=male, 2=female

The third column "APOE_genotype" is Apolipoprotein-E. The values are:
1 = e3, e3
2 = e3, e4
3 = e3, e2
4 = e4, e4
5 = e4, e2
6 = e2, e2

Case/Control_Neuropathological
Variable Number 27
Variable Name NPDXONE
Short Descriptor Primary Neuropathological Diagnosis
Variable Type Integer
Allowable Codes 1 – 5
1 = Normal Brain
2 = Alzheimer’s disease – Definite (e.g., using CERAD or
other neuropathological criteria)
3 = Alzheimer’s disease – Probable (e.g., using CERAD or
other neuropathological criteria)
4 = Alzheimer’s disease – Possible (e.g., using CERAD or
other neuropathological criteria)
5 = Autopsy report pending
6 = Other

Case/Control_Clinical
Variable Number 17
Variable Name CLNDXONE
Short Descriptor Primary Clinical Dementia Diagnosis at Death
Variable Type Integer
Allowable Codes 0 – 2
0 = Subject did not have dementia
1 = Alzheimer’s disease (e.g. NINCDS “probable Alzheimer’s
disease” or DSM IV “dementia of the Alzheimer’s type”)
2 = Alzheimer’s disease with other conditions or variations in
course (e.g., NINCDS “possible Alzheimer’s disease”,
DSM IV multiple etiologies where Alzheimer’s is the
predominate cause)
3 = Other
Missing Code 9 = Missing/Unknown

Age_of_onset
Variable Number 11
Variable Name AGEDEM
Short Descriptor If demented, at what age did the subject develop dementia
symptoms?
Variable Type Integer
Allowable Codes 0 – 130, 888 (not applicable)
Missing Code 999
Comment Refers to age of onset of dementia symptoms, not age at which
diagnosis was made.
** I replaced “888” and “999” with “NA”.

Age of death
Age of death = Death Year - Birth Year

Variable Number 14
Variable Name DEATHYR
Short Descriptor Subject’s date of death: Year
Variable Type Integer
Allowable Codes > 1950 and < 2010
Missing Codes 9999

Variable Number 6
Variable Name BIRTHYR
Short Descriptor Subject’s date of birth: Year
Variable Type Integer
Allowable Codes > 1875
Missing Codes 9999

Age_of_last_visit
Age of last visit = Eval Year - Birth Year

Variable Number 3
Variable Name EVALYEAR
Short Descriptor Date of evaluation: Year
Variable Type Integer
Allowable Codes > 1965
Missing Codes 9999
** I used the most recent Eval Year information.

Age_(unspecified)
NA

Last MMSE
Variable Number 6
Variable Name MMSE
Short Descriptor Mini-Mental State Exam score (0 to 30)
Variable Type Integer
Allowable Codes 0 – 30, 88 (not collected/administered)
Missing Code 99 = Missing/Unknown/Incomplete
** I replaced “88” and “99” with “NA”.