Dataset

NG00023 - ADC2- Alzheimer Disease Center Dataset 2

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Overview

The NIA ADC cohort included subjects ascertained and evaluated by the clinical and neuropathology cores of the 39 past and present NIA-funded Alzheimer's Disease Centers (ADC).  Data collection is coordinated by the National Alzheimer’s Coordinating Center (NACC).  NACC coordinates collection of phenotype data from the ADCs, cleans all data, coordinates implementation of definitions of AD cases and controls, and coordinates collection of samples. Biological specimens are collected, stored, and distributed by the National Cell Repository for Alzheimer’s Disease (NCRAD).

This GWAS dataset, ADC2, is the second set of ADC genotyped subjects used by the Alzheimer's Disease Genetics Consortium (ADGC) to identify genes associated with an increased risk of developing late-onset Alzheimer’s disease (LOAD). ADC2 was first published in Naj et al. For deeper phenotypes, contact NACC.

Detailed information about the dataset is provided in the following document: NG00023_ADC2_README.txt

This dataset was updated 12/18/2018. See README file for additional information.

Molecular Data Type

Disease

AD
Submission date: 
8/1/2012
Samples

Cases- 688
Controls- 116
MCI- 16
NA/Unknown- 106

Total- 926

Phenotypes
Markers

525723

Platform
PI Information