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2021
Baird DA
,
Liu JZ
,
Zheng J
,
Sieberts SK
,
Perumal T
,
Elsworth B
,
Richardson TG
,
Chen C-Y
,
Carrasquillo MM
,
Allen M
et al.
. 2021.
Identifying drug targets for neurological and psychiatric disease via genetics and the brain transcriptome.
.
PLoS Genet. 17(1):e1009224.
PubMed
Griswold AJ
,
Celis K
,
Bussies PL
,
Rajabli F
,
Whitehead PL
,
Hamilton-Nelson KL
,
Beecham GW
,
Dykxhoorn DM
,
Nuytemans K
,
Wang L
et al.
. 2021.
Increased APOE ε4 expression is associated with the difference in Alzheimer's disease risk from diverse ancestral backgrounds.
.
Alzheimers Dement. 17(7):1179-1188.
PubMed
Wingo AP
,
Liu Y
,
Gerasimov ES
,
Gockley J
,
Logsdon BA
,
Duong DM
,
Dammer EB
,
Robins C
,
Beach TG
,
Reiman EM
et al.
. 2021.
Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer's disease pathogenesis.
.
Nat Genet. 53(2):143-146.
PubMed
Novikova G
,
Kapoor M
,
Tcw J
,
Abud EM
,
Efthymiou AG
,
Chen SX
,
Cheng H
,
Fullard JF
,
Bendl J
,
Liu Y
et al.
. 2021.
Integration of Alzheimer's disease genetics and myeloid genomics identifies disease risk regulatory elements and genes.
.
Nat Commun. 12(1):1610.
PubMed
Kirola L
,
Budde JP
,
Wang F
,
Norton J
,
Morris JC
,
Cruchaga C
,
Fernández MVictoria
. 2021.
Lack of evidence supporting a role for DPP6 sequence variants in Alzheimer's disease in the European American population.
.
Acta Neuropathol. 141(4):623-624.
PubMed
Rajabli F
,
Feliciano-Astacio BE
,
Cukier HN
,
Wang L
,
Griswold AJ
,
Hamilton-Nelson KL
,
Adams LD
,
Rodriguez VC
,
Mena PR
,
Tejada S
et al.
. 2021.
Linkage of Alzheimer disease families with Puerto Rican ancestry identifies a chromosome 9 locus.
.
Neurobiol Aging. 104:115.e1-115.e7.
PubMed
Moreno-Grau S
,
Fernández MVictoria
,
de Rojas I
,
García-González P
,
Hernández I
,
Farias F
,
Budde JP
,
Quintela I
,
Madrid L
,
González-Perez A
et al.
. 2021.
Long runs of homozygosity are associated with Alzheimer's disease.
.
Transl Psychiatry. 11(1):142.
PubMed
Ramos J
,
Chowdhury AR
,
Caywood LJ
,
Prough M
,
M Fuzzell D
,
Fuzzell S
,
Miskimen K
,
Whitehead PL
,
Adams LD
,
Laux R
et al.
. 2021.
Lower Levels of Education Are Associated with Cognitive Impairment in the Old Order Amish.
.
J Alzheimers Dis. 79(1):451-458.
PubMed
Malik R
,
Georgakis MK
,
Neitzel J
,
Rannikmäe K
,
Ewers M
,
Seshadri S
,
Sudlow CLM
,
Dichgans M
. 2021.
Midlife vascular risk factors and risk of incident dementia: Longitudinal cohort and Mendelian randomization analyses in the UK Biobank.
.
Alzheimers Dement. 17(9):1422-1431.
PubMed
Blue EE
,
Thornton TA
,
Kooperberg C
,
Liu S
,
Wactawski-Wende J
,
Manson JA
,
Kuller L
,
Hayden K
,
Reiner AP
. 2021.
Non-coding variants in MYH11, FZD3, and SORCS3 are associated with dementia in women.
.
Alzheimers Dement. 17(2):215-225.
PubMed
Kunkle BW
,
Schmidt M
,
Klein H-U
,
Naj AC
,
Hamilton-Nelson KL
,
Larson EB
,
Evans DA
,
De Jager PL
,
Crane PK
,
Buxbaum JD
et al.
. 2021.
Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis.
.
JAMA Neurol. 78(1):102-113.
PubMed
Dewan R
,
Chia R
,
Ding J
,
Hickman RA
,
Stein TD
,
Abramzon Y
,
Ahmed S
,
Sabir MS
,
Portley MK
,
Tucci A
et al.
. 2021.
Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis.
.
Neuron. 109(3):448-460.e4.
PubMed
Damotte V
,
van der Lee SJ
,
Chouraki V
,
Grenier-Boley B
,
Simino J
,
Adams H
,
Tosto G
,
White C
,
Terzikhan N
,
Cruchaga C
et al.
. 2021.
Plasma amyloid β levels are driven by genetic variants near APOE, BACE1, APP, PSEN2: A genome-wide association study in over 12,000 non-demented participants.
.
Alzheimers Dement. 17(10):1663-1674.
PubMed
Brickman AM
,
Manly JJ
,
Honig LS
,
Sanchez D
,
Reyes-Dumeyer D
,
Lantigua RA
,
Lao PJ
,
Stern Y
,
Vonsattel JPaul
,
Teich AF
et al.
. 2021.
Plasma p-tau181, p-tau217, and other blood-based Alzheimer's disease biomarkers in a multi-ethnic, community study.
.
Alzheimers Dement. 17(8):1353-1364.
PubMed
Sariya S
,
Felsky D
,
Reyes-Dumeyer D
,
Lali R
,
Lantigua RA
,
Vardarajan B
,
Jimenez-Velazquez IZ
,
Haines JL
,
Shellenberg GD
,
Pericak-Vance MA
et al.
. 2021.
Polygenic Risk Score for Alzheimer's Disease in Caribbean Hispanics.
.
Ann Neurol. 90(3):366-376.
PubMed
Ramos-Miguel A
,
Jones AA
,
Petyuk VA
,
Barakauskas VE
,
Barr AM
,
Leurgans SE
,
De Jager PL
,
Casaletto KB
,
Schneider JA
,
Bennett DA
et al.
. 2021.
Proteomic identification of select protein variants of the SNARE interactome associated with cognitive reserve in a large community sample.
.
Acta Neuropathol. 141(5):755-770.
PubMed
Zhan L
,
Li J
,
Jew B
,
Sul JHoon
. 2021.
Rare variants in the endocytic pathway are associated with Alzheimer's disease, its related phenotypes, and functional consequences.
.
PLoS Genet. 17(9):e1009772.
PubMed
Patel D
,
Zhang X
,
Farrell JJ
,
Lunetta KL
,
Farrer LA
. 2021.
Set-Based Rare Variant Expression Quantitative Trait Loci in Blood and Brain from Alzheimer Disease Study Participants.
.
Genes (Basel). 12(3)
PubMed
Kim M
,
Bao J
,
Liu K
,
Park B-Y
,
Park H
,
Baik JYoung
,
Shen L
. 2021.
A structural enriched functional network: An application to predict brain cognitive performance.
.
Med Image Anal. 71:102026.
PubMed
Wang S
,
Lindroth H
,
Chan C
,
Greene R
,
Serrano-Andrews P
,
Khan S
,
Rios G
,
Jabbari S
,
Lim J
,
Saykin AJ
et al.
. 2021.
A Systematic Review of Delirium Biomarkers and Their Alignment with the NIA-AA Research Framework.
.
J Am Geriatr Soc. 69(1):255-263.
PubMed
Wang M
,
Li A
,
Sekiya M
,
Beckmann ND
,
Quan X
,
Schrode N
,
Fernando MB
,
Yu A
,
Zhu L
,
Cao J
et al.
. 2021.
Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer's Disease.
.
Neuron. 109(2):257-272.e14.
PubMed
Amlie-Wolf A
,
Kuksa PP
,
Lee C-Y
,
Mlynarski E
,
Leung YYee
,
San Wang L-
. 2021.
Using INFERNO to Infer the Molecular Mechanisms Underlying Noncoding Genetic Associations.
.
Methods Mol Biol. 2254:73-91.
PubMed
Lyon MS
,
Andrews SJ
,
Elsworth B
,
Gaunt TR
,
Hemani G
,
Marcora E
. 2021.
The variant call format provides efficient and robust storage of GWAS summary statistics.
.
Genome Biol. 22(1):32.
PubMed
2020
Lancour D
,
Dupuis J
,
Mayeux R
,
Haines JL
,
Pericak-Vance MA
,
Schellenberg GC
,
Crovella M
,
Farrer LA
,
Kasif S
. 2020.
Analysis of brain region-specific co-expression networks reveals clustering of established and novel genes associated with Alzheimer disease.
.
Alzheimers Res Ther. 12(1):103.
PubMed
Davis AA
,
Inman CE
,
Wargel ZM
,
Dube U
,
Freeberg BM
,
Galluppi A
,
Haines JN
,
Dhavale DD
,
Miller R
,
Choudhury FA
et al.
. 2020.
APOE genotype regulates pathology and disease progression in synucleinopathy.
.
Sci Transl Med. 12(529)
PubMed
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