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Goate, Alison M
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2021
Andrews SJ
,
Fulton-Howard B
,
O'Reilly P
,
Marcora E
,
Goate AM
. 2021.
Causal Associations Between Modifiable Risk Factors and the Alzheimer's Phenome.
.
Ann Neurol. 89(1):54-65.
PubMed
Fulton-Howard B
,
Goate AM
,
Adelson RP
,
Koppel J
,
Gordon ML
,
Barzilai N
,
Atzmon G
,
Davies P
,
Freudenberg-Hua Y
. 2021.
Greater effect of polygenic risk score for Alzheimer's disease among younger cases who are apolipoprotein E-ε4 carriers.
.
Neurobiol Aging. 99:101.e1-101.e9.
PubMed
Wu HMan
,
Goate AM
,
O'Reilly PF
. 2021.
Heterogeneous effects of genetic risk for Alzheimer's disease on the phenome.
.
Transl Psychiatry. 11(1):406.
PubMed
Novikova G
,
Kapoor M
,
Tcw J
,
Abud EM
,
Efthymiou AG
,
Chen SX
,
Cheng H
,
Fullard JF
,
Bendl J
,
Liu Y
et al.
. 2021.
Integration of Alzheimer's disease genetics and myeloid genomics identifies disease risk regulatory elements and genes.
.
Nat Commun. 12(1):1610.
PubMed
Kunkle BW
,
Schmidt M
,
Klein H-U
,
Naj AC
,
Hamilton-Nelson KL
,
Larson EB
,
Evans DA
,
De Jager PL
,
Crane PK
,
Buxbaum JD
et al.
. 2021.
Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis.
.
JAMA Neurol. 78(1):102-113.
PubMed
2020
Neuner SM
,
Tcw J
,
Goate AM
. 2020.
Genetic architecture of Alzheimer's disease.
.
Neurobiol Dis. 143:104976.
PubMed
Podleśny-Drabiniok A
,
Marcora E
,
Goate AM
. 2020.
Microglial Phagocytosis: A Disease-Associated Process Emerging from Alzheimer's Disease Genetics.
.
Trends Neurosci. 43(12):965-979.
PubMed
Zhao L
,
Zhang Z
,
Rodriguez SMBarral
,
Vardarajan BN
,
Renton AE
,
Goate AM
,
Mayeux R
,
Wang GT
,
Leal SM
. 2020.
A quantitative trait rare variant nonparametric linkage method with application to age-at-onset of Alzheimer's disease.
.
Eur J Hum Genet. 28(12):1734-1742.
PubMed
Zhang Q
,
Sidorenko J
,
Couvy-Duchesne B
,
Marioni RE
,
Wright MJ
,
Goate AM
,
Marcora E
,
Huang K-L
,
Porter T
,
Laws SM
et al.
. 2020.
Risk prediction of late-onset Alzheimer's disease implies an oligogenic architecture.
.
Nat Commun. 11(1):4799.
PubMed
Hsu S
,
Pimenova AA
,
Hayes K
,
Villa JA
,
Rosene MJ
,
Jere M
,
Goate AM
,
Karch CM
. 2020.
Systematic validation of variants of unknown significance in APP, PSEN1 and PSEN2.
.
Neurobiol Dis. 139:104817.
PubMed
2019
Baker E
,
Sims R
,
Leonenko G
,
Frizzati A
,
Harwood JC
,
Grozeva D
,
Morgan K
,
Passmore P
,
Holmes C
,
Powell J
et al.
. 2019.
Gene-based analysis in HRC imputed genome wide association data identifies three novel genes for Alzheimer's disease.
.
PLoS One. 14(7):e0218111.
PubMed
Kunkle BW
,
Grenier-Boley B
,
Sims R
,
Bis JC
,
Damotte V
,
Naj AC
,
Boland A
,
Vronskaya M
,
van der Lee SJ
,
Amlie-Wolf A
et al.
. 2019.
Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.
.
Nat Genet. 51(3):414-430.
PubMed
Liu Y
,
Wang M
,
Marcora EM
,
Zhang B
,
Goate AM
. 2019.
Promoter DNA hypermethylation - Implications for Alzheimer's disease.
.
Neurosci Lett. 711:134403.
PubMed
Dumitrescu L
,
Barnes LL
,
Thambisetty M
,
Beecham G
,
Kunkle B
,
Bush WS
,
Gifford KA
,
Chibnik LB
,
Mukherjee S
,
De Jager PL
et al.
. 2019.
Sex differences in the genetic predictors of Alzheimer's pathology.
.
Brain. 142(9):2581-2589.
PubMed
2018
Fernández MV
,
Budde J
,
Del-Aguila JL
,
Ibañez L
,
Deming Y
,
Harari O
,
Norton J
,
Morris JC
,
Goate AM
,
Cruchaga C
. 2018.
Evaluation of Gene-Based Family-Based Methods to Detect Novel Genes Associated With Familial Late Onset Alzheimer Disease.
.
Front Neurosci. 12:209.
PubMed
Marioni RE
,
Harris SE
,
Zhang Q
,
McRae AF
,
Hagenaars SP
,
W Hill D
,
Davies G
,
Ritchie CW
,
Gale CR
,
Starr JM
et al.
. 2018.
GWAS on family history of Alzheimer's disease.
.
Transl Psychiatry. 8(1):99.
PubMed
Deming Y
,
Dumitrescu L
,
Barnes LL
,
Thambisetty M
,
Kunkle B
,
Gifford KA
,
Bush WS
,
Chibnik LB
,
Mukherjee S
,
De Jager PL
et al.
. 2018.
Sex-specific genetic predictors of Alzheimer's disease biomarkers.
.
Acta Neuropathol. 136(6):857-872.
PubMed
2016
Kunkle BW
,
Jaworski J
,
Barral S
,
Vardarajan B
,
Beecham GW
,
Martin ER
,
Cantwell LS
,
Partch A
,
Bird TD
,
Raskind WH
et al.
. 2016.
Genome-wide linkage analyses of non-Hispanic white families identify novel loci for familial late-onset Alzheimer's disease.
.
Alzheimers Dement. 12(1):2-10.
PubMed
2015
Barral S
,
Cheng R
,
Reitz C
,
Vardarajan B
,
Lee J
,
Kunkle B
,
Beecham G
,
Cantwell LS
,
Pericak-Vance MA
,
Farrer LA
et al.
. 2015.
Linkage analyses in Caribbean Hispanic families identify novel loci associated with familial late-onset Alzheimer's disease.
.
Alzheimers Dement. 11(12):1397-1406.
PubMed
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