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Alzheimer Disease
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2021
Horimoto ARVR
,
Xue D
,
Thornton TA
,
Blue EE
. 2021.
Admixture mapping reveals the association between Native American ancestry at 3q13.11 and reduced risk of Alzheimer's disease in Caribbean Hispanics.
.
Alzheimers Res Ther. 13(1):122.
PubMed
Deters KD
,
Napolioni V
,
Sperling RA
,
Greicius MD
,
Mayeux R
,
Hohman T
,
Mormino EC
. 2021.
Amyloid PET Imaging in Self-Identified Non-Hispanic Black Participants of the Anti-Amyloid in Asymptomatic Alzheimer's Disease (A4) Study.
.
Neurology. 96(11):e1491-e1500.
PubMed
Granot-Hershkovitz E
,
Tarraf W
,
Kurniansyah N
,
Daviglus M
,
Isasi CR
,
Kaplan R
,
Lamar M
,
Perreira KM
,
Wassertheil-Smoller S
,
Stickel A
et al.
. 2021.
APOE alleles' association with cognitive function differs across Hispanic/Latino groups and genetic ancestry in the study of Latinos-investigation of neurocognitive aging (HCHS/SOL).
.
Alzheimers Dement. 17(3):466-474.
PubMed
Rizvi B
,
Lao PJ
,
Chesebro AG
,
Dworkin JD
,
Amarante E
,
Beato JM
,
Gutierrez J
,
Zahodne LB
,
Schupf N
,
Manly JJ
et al.
. 2021.
Association of Regional White Matter Hyperintensities With Longitudinal Alzheimer-Like Pattern of Neurodegeneration in Older Adults.
.
JAMA Netw Open. 4(10):e2125166.
PubMed
Walker JM
,
Fudym Y
,
Farrell K
,
Iida MA
,
Bieniek KF
,
Seshadri S
,
White CL
,
Crary JF
,
Richardson TE
. 2021.
Asymmetry of Hippocampal Tau Pathology in Primary Age-Related Tauopathy and Alzheimer Disease.
.
J Neuropathol Exp Neurol. 80(5):436-445.
PubMed
Kim JPyo
,
Kim B-H
,
Bice PJ
,
Seo SWon
,
Bennett DA
,
Saykin AJ
,
Nho K
. 2021.
BMI1 is associated with CS8F amyloid-β and rates of cognitive decline in Alzheimer's disease.
.
Alzheimers Res Ther. 13(1):164.
PubMed
Andrews SJ
,
Fulton-Howard B
,
O'Reilly P
,
Marcora E
,
Goate AM
. 2021.
Causal Associations Between Modifiable Risk Factors and the Alzheimer's Phenome.
.
Ann Neurol. 89(1):54-65.
PubMed
Patel D
,
Zhang X
,
Farrell JJ
,
Chung J
,
Stein TD
,
Lunetta KL
,
Farrer LA
. 2021.
Cell-type-specific expression quantitative trait loci associated with Alzheimer disease in blood and brain tissue.
.
Transl Psychiatry. 11(1):250.
PubMed
de Erausquin GA
,
Snyder H
,
Carrillo M
,
Hosseini AA
,
Brugha TS
,
Seshadri S
. 2021.
The chronic neuropsychiatric sequelae of COVID-19: The need for a prospective study of viral impact on brain functioning.
.
Alzheimers Dement. 17(6):1056-1065.
PubMed
de Rojas I
,
Moreno-Grau S
,
Tesi N
,
Grenier-Boley B
,
Andrade V
,
Jansen IE
,
Pedersen NL
,
Stringa N
,
Zettergren A
,
Hernández I
et al.
. 2021.
Common variants in Alzheimer's disease and risk stratification by polygenic risk scores.
.
Nat Commun. 12(1):3417.
PubMed
Patrick E
,
Olah M
,
Taga M
,
Klein H-U
,
Xu J
,
White CC
,
Felsky D
,
Agrawal S
,
Gaiteri C
,
Chibnik LB
et al.
. 2021.
A cortical immune network map identifies distinct microglial transcriptional programs associated with β-amyloid and Tau pathologies.
.
Transl Psychiatry. 11(1):50.
PubMed
Laverde-Paz MJuliana
,
Nuytemans K
,
Wang L
,
Vance JM
,
Pericak-Vance MA
,
Dykxhoorn DM
,
Cukier HN
. 2021.
Derivation of stem cell line UMi028-A-2 containing a CRISPR/Cas9 induced Alzheimer's disease risk variant p.S1038C in the TTC3 gene.
.
Stem Cell Res. 52:102258.
PubMed
Marca-Ysabel MVictoria
,
Rajabli F
,
Cornejo-Olivas M
,
Whitehead PG
,
Hofmann NK
,
Manrique MZaida Illa
,
Otani DMartin Vel
,
Neyra AKarina Mil
,
Suarez SCastro
,
Vega MMeza
et al.
. 2021.
Dissecting the role of Amerindian genetic ancestry and the ApoE ε4 allele on Alzheimer disease in an admixed Peruvian population.
.
Neurobiol Aging. 101:298.e11-298.e15.
PubMed
Ayodele T
,
Rogaeva E
,
Kurup JT
,
Beecham G
,
Reitz C
. 2021.
Early-Onset Alzheimer's Disease: What Is Missing in Research?
Curr Neurol Neurosci Rep. 21(2):4.
PubMed
Chia R
,
Sabir MS
,
Bandres-Ciga S
,
Saez-Atienzar S
,
Reynolds RH
,
Gustavsson E
,
Walton RL
,
Ahmed S
,
Viollet C
,
Ding J
et al.
. 2021.
Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture.
.
Nat Genet. 53(3):294-303.
PubMed
Yan Q
,
Nho K
,
Del-Aguila JL
,
Wang X
,
Risacher SL
,
Fan K-H
,
Snitz BE
,
Aizenstein HJ
,
Mathis CA
,
Lopez OL
et al.
. 2021.
Genome-wide association study of brain amyloid deposition as measured by Pittsburgh Compound-B (PiB)-PET imaging.
.
Mol Psychiatry. 26(1):309-321.
PubMed
Wang H
,
Bennett DA
,
De Jager PL
,
Zhang Q-Y
,
Zhang H-Y
. 2021.
Genome-wide epistasis analysis for Alzheimer's disease and implications for genetic risk prediction.
.
Alzheimers Res Ther. 13(1):55.
PubMed
Fulton-Howard B
,
Goate AM
,
Adelson RP
,
Koppel J
,
Gordon ML
,
Barzilai N
,
Atzmon G
,
Davies P
,
Freudenberg-Hua Y
. 2021.
Greater effect of polygenic risk score for Alzheimer's disease among younger cases who are apolipoprotein E-ε4 carriers.
.
Neurobiol Aging. 99:101.e1-101.e9.
PubMed
Wu HMan
,
Goate AM
,
O'Reilly PF
. 2021.
Heterogeneous effects of genetic risk for Alzheimer's disease on the phenome.
.
Transl Psychiatry. 11(1):406.
PubMed
Baird DA
,
Liu JZ
,
Zheng J
,
Sieberts SK
,
Perumal T
,
Elsworth B
,
Richardson TG
,
Chen C-Y
,
Carrasquillo MM
,
Allen M
et al.
. 2021.
Identifying drug targets for neurological and psychiatric disease via genetics and the brain transcriptome.
.
PLoS Genet. 17(1):e1009224.
PubMed
Xu H
,
O'Reilly M
,
Gibbons GS
,
Changolkar L
,
McBride JD
,
Riddle DM
,
Zhang B
,
Stieber A
,
Nirschl J
,
Kim S-J
et al.
. 2021.
In vitro amplification of pathogenic tau conserves disease-specific bioactive characteristics.
.
Acta Neuropathol. 141(2):193-215.
PubMed
Griswold AJ
,
Celis K
,
Bussies PL
,
Rajabli F
,
Whitehead PL
,
Hamilton-Nelson KL
,
Beecham GW
,
Dykxhoorn DM
,
Nuytemans K
,
Wang L
et al.
. 2021.
Increased APOE ε4 expression is associated with the difference in Alzheimer's disease risk from diverse ancestral backgrounds.
.
Alzheimers Dement. 17(7):1179-1188.
PubMed
Wingo AP
,
Liu Y
,
Gerasimov ES
,
Gockley J
,
Logsdon BA
,
Duong DM
,
Dammer EB
,
Robins C
,
Beach TG
,
Reiman EM
et al.
. 2021.
Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer's disease pathogenesis.
.
Nat Genet. 53(2):143-146.
PubMed
Novikova G
,
Kapoor M
,
Tcw J
,
Abud EM
,
Efthymiou AG
,
Chen SX
,
Cheng H
,
Fullard JF
,
Bendl J
,
Liu Y
et al.
. 2021.
Integration of Alzheimer's disease genetics and myeloid genomics identifies disease risk regulatory elements and genes.
.
Nat Commun. 12(1):1610.
PubMed
Kirola L
,
Budde JP
,
Wang F
,
Norton J
,
Morris JC
,
Cruchaga C
,
Fernández MVictoria
. 2021.
Lack of evidence supporting a role for DPP6 sequence variants in Alzheimer's disease in the European American population.
.
Acta Neuropathol. 141(4):623-624.
PubMed
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