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Author Title Type [ Year(Desc)]
Filters: Keyword is Aged, 80 and over  [Clear All Filters]
2015
Barral S, Cheng R, Reitz C, Vardarajan B, Lee J, Kunkle B, Beecham G, Cantwell LS, Pericak-Vance MA, Farrer LA et al..  2015.  Linkage analyses in Caribbean Hispanic families identify novel loci associated with familial late-onset Alzheimer's disease.. Alzheimers Dement. 11(12):1397-1406.
2016
Kunkle BW, Jaworski J, Barral S, Vardarajan B, Beecham GW, Martin ER, Cantwell LS, Partch A, Bird TD, Raskind WH et al..  2016.  Genome-wide linkage analyses of non-Hispanic white families identify novel loci for familial late-onset Alzheimer's disease.. Alzheimers Dement. 12(1):2-10.
2017
Crane PK, Foroud T, Montine TJ, Larson EB.  2017.  Alzheimer's Disease Sequencing Project discovery and replication criteria for cases and controls: Data from a community-based prospective cohort study with autopsy follow-up.. Alzheimers Dement. 13(12):1410-1413.
Fernández MVictoria, Kim JHun, Budde JP, Black K, Medvedeva A, Saef B, Deming Y, Del-Aguila J, Ibañez L, Dube U et al..  2017.  Analysis of neurodegenerative Mendelian genes in clinically diagnosed Alzheimer Disease.. PLoS Genet. 13(11):e1007045.
Adams SL, Benayoun L, Tilton K, Chavez OR, Himali JJ, Blusztajn JKrzysztof, Seshadri S, Delalle I.  2017.  Methionine Sulfoxide Reductase-B3 (MsrB3) Protein Associates with Synaptic Vesicles and its Expression Changes in the Hippocampi of Alzheimer's Disease Patients.. J Alzheimers Dis. 60(1):43-56.
2018
Rajabli F, Feliciano BE, Celis K, Hamilton-Nelson KL, Whitehead PL, Adams LD, Bussies PL, Manrique CP, Rodriguez A, Rodriguez V et al..  2018.  Ancestral origin of ApoE ε4 Alzheimer disease risk in Puerto Rican and African American populations.. PLoS Genet. 14(12):e1007791.
Blue EE, Bis JC, Dorschner MO, Tsuang DW, Barral SM, Beecham G, Below JE, Bush WS, Butkiewicz M, Cruchaga C et al..  2018.  Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer's Disease Sequencing Project.. Dement Geriatr Cogn Disord. 45(1-2):1-17.
Jiang S, Wen N, Li Z, Dube U, Del Aguila J, Budde J, Martinez R, Hsu S, Fernández MV, Cairns NJ et al..  2018.  Integrative system biology analyses of CRISPR-edited iPSC-derived neurons and human brains reveal deficiencies of presynaptic signaling in FTLD and PSP.. Transl Psychiatry. 8(1):265.
Deming Y, Dumitrescu L, Barnes LL, Thambisetty M, Kunkle B, Gifford KA, Bush WS, Chibnik LB, Mukherjee S, De Jager PL et al..  2018.  Sex-specific genetic predictors of Alzheimer's disease biomarkers.. Acta Neuropathol. 136(6):857-872.
Blue EE, Yu C-E, Thornton TA, Chapman NH, Kernfeld E, Jiang N, Shively KM, Buckingham KJ, Marvin CT, Bamshad MJ et al..  2018.  Variants regulating ZBTB4 are associated with age-at-onset of Alzheimer's disease.. Genes Brain Behav. 17(6):e12429.
2019
Mishra A, Chauhan G, Violleau M-H, Vojinovic D, Jian X, Bis JC, Li S, Saba Y, Grenier-Boley B, Yang Q et al..  2019.  Association of variants in HTRA1 and NOTCH3 with MRI-defined extremes of cerebral small vessel disease in older subjects.. Brain. 142(4):1009-1023.
Bentley AR, Sung YJ, Brown MR, Winkler TW, Kraja AT, Ntalla I, Schwander K, Chasman DI, Lim E, Deng X et al..  2019.  Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.. Nat Genet. 51(4):636-648.
Tan CHong, Bonham LW, Fan CChieh, Mormino EC, Sugrue LP, Broce IJ, Hess CP, Yokoyama JS, Rabinovici GD, Miller BL et al..  2019.  Polygenic hazard score, amyloid deposition and Alzheimer's neurodegeneration.. Brain. 142(2):460-470.
Del-Aguila JL, Li Z, Dube U, Mihindukulasuriya KA, Budde JP, Fernández MVictoria, Ibañez L, Bradley J, Wang F, Bergmann K et al..  2019.  A single-nuclei RNA sequencing study of Mendelian and sporadic AD in the human brain.. Alzheimers Res Ther. 11(1):71.
Katsumata Y, Nelson PT, Estus S, Fardo DW.  2019.  Translating Alzheimer's disease-associated polymorphisms into functional candidates: a survey of IGAP genes and SNPs.. Neurobiol Aging. 74:135-146.
2020
Raghavan NS, Dumitrescu L, Mormino E, Mahoney ER, Lee AJ, Gao Y, Bilgel M, Goldstein D, Harrison T, Engelman CD et al..  2020.  Association Between Common Variants in RBFOX1, an RNA-Binding Protein, and Brain Amyloidosis in Early and Preclinical Alzheimer Disease.. JAMA Neurol. 77(10):1288-1298.
Belloy ME, Napolioni V, Han SS, Le Guen Y, Greicius MD.  2020.  Association of Klotho-VS Heterozygosity With Risk of Alzheimer Disease in Individuals Who Carry APOE4.. JAMA Neurol. 77(7):849-862.
Blue EE, Cheng A, Chen S, Yu C-E.  2020.  Association of Uncommon, Noncoding Variants in the APOE Region With Risk of Alzheimer Disease in Adults of European Ancestry.. JAMA Netw Open. 3(10):e2017666.
Friedberg JS, Aytan N, Cherry JD, Xia W, Standring OJ, Alvarez VE, Nicks R, Svirsky S, Meng G, Jun G et al..  2020.  Associations between brain inflammatory profiles and human neuropathology are altered based on apolipoprotein E ε4 genotype.. Sci Rep. 10(1):2924.
Wang L, Qiao Y, Zhang H, Zhang Y, Hua J, Jin S, Liu G.  2020.  Circulating Vitamin D Levels and Alzheimer's Disease: A Mendelian Randomization Study in the IGAP and UK Biobank.. J Alzheimers Dis. 73(2):609-618.
Olive C, Ibañez L, Farias FHGeraldo, Wang F, Budde JP, Norton JB, Gentsch J, Morris JC, Li Z, Dube U et al..  2020.  Examination of the Effect of Rare Variants in TREM2, ABI3, and PLCG2 in LOAD Through Multiple Phenotypes.. J Alzheimers Dis. 77(4):1469-1482.
Reiman EM, Arboleda-Velasquez JF, Quiroz YT, Huentelman MJ, Beach TG, Caselli RJ, Chen Y, Su Y, Myers AJ, Hardy J et al..  2020.  Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study.. Nat Commun. 11(1):667.
Ibañez L, Bahena JA, Yang C, Dube U, Farias FHG, Budde JP, Bergmann K, Brenner-Webster C, Morris JC, Perrin RJ et al..  2020.  Functional genomic analyses uncover APOE-mediated regulation of brain and cerebrospinal fluid beta-amyloid levels in Parkinson disease.. Acta Neuropathol Commun. 8(1):196.
Hofer E, Roshchupkin GV, Adams HHH, Knol MJ, Lin H, Li S, Zare H, Ahmad S, Armstrong NJ, Satizabal CL et al..  2020.  Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults.. Nat Commun. 11(1):4796.
Mukherjee S, Mez J, Trittschuh EH, Saykin AJ, Gibbons LE, Fardo DW, Wessels M, Bauman J, Moore M, Choi S-E et al..  2020.  Genetic data and cognitively defined late-onset Alzheimer's disease subgroups.. Mol Psychiatry. 25(11):2942-2951.

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