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Quantitative Trait Loci
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A
Saad M
,
Wijsman EM
. 2019.
Association score testing for rare variants and binary traits in family data with shared controls.
.
Brief Bioinform. 20(1):245-253.
PubMed
C
Patel D
,
Zhang X
,
Farrell JJ
,
Chung J
,
Stein TD
,
Lunetta KL
,
Farrer LA
. 2021.
Cell-type-specific expression quantitative trait loci associated with Alzheimer disease in blood and brain tissue.
.
Transl Psychiatry. 11(1):250.
PubMed
Keys KL
,
C Y Mak A
,
White MJ
,
Eckalbar WL
,
Dahl AW
,
Mefford J
,
Mikhaylova AV
,
Contreras MG
,
Elhawary JR
,
Eng C
et al.
. 2020.
On the cross-population generalizability of gene expression prediction models.
.
PLoS Genet. 16(8):e1008927.
PubMed
G
Robins C
,
Liu Y
,
Fan W
,
Duong DM
,
Meigs J
,
Harerimana NV
,
Gerasimov ES
,
Dammer EB
,
Cutler DJ
,
Beach TG
et al.
. 2021.
Genetic control of the human brain proteome.
.
Am J Hum Genet. 108(3):400-410.
PubMed
Huan T
,
Joehanes R
,
Song C
,
Peng F
,
Guo Y
,
Mendelson M
,
Yao C
,
Liu C
,
Ma J
,
Richard M
et al.
. 2019.
Genome-wide identification of DNA methylation QTLs in whole blood highlights pathways for cardiovascular disease.
.
Nat Commun. 10(1):4267.
PubMed
I
Baird DA
,
Liu JZ
,
Zheng J
,
Sieberts SK
,
Perumal T
,
Elsworth B
,
Richardson TG
,
Chen C-Y
,
Carrasquillo MM
,
Allen M
et al.
. 2021.
Identifying drug targets for neurological and psychiatric disease via genetics and the brain transcriptome.
.
PLoS Genet. 17(1):e1009224.
PubMed
Amlie-Wolf A
,
Tang M
,
Mlynarski EE
,
Kuksa PP
,
Valladares O
,
Katanić Ž
,
Tsuang D
,
Brown CD
,
Schellenberg GD
,
San Wang L-
. 2018.
INFERNO: inferring the molecular mechanisms of noncoding genetic variants.
.
Nucleic Acids Res. 46(17):8740-8753.
PubMed
Wingo AP
,
Liu Y
,
Gerasimov ES
,
Gockley J
,
Logsdon BA
,
Duong DM
,
Dammer EB
,
Robins C
,
Beach TG
,
Reiman EM
et al.
. 2021.
Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer's disease pathogenesis.
.
Nat Genet. 53(2):143-146.
PubMed
Q
Zhao L
,
Zhang Z
,
Rodriguez SMBarral
,
Vardarajan BN
,
Renton AE
,
Goate AM
,
Mayeux R
,
Wang GT
,
Leal SM
. 2020.
A quantitative trait rare variant nonparametric linkage method with application to age-at-onset of Alzheimer's disease.
.
Eur J Hum Genet. 28(12):1734-1742.
PubMed
S
Patel D
,
Zhang X
,
Farrell JJ
,
Lunetta KL
,
Farrer LA
. 2021.
Set-Based Rare Variant Expression Quantitative Trait Loci in Blood and Brain from Alzheimer Disease Study Participants.
.
Genes (Basel). 12(3)
PubMed
Kuksa PP
,
Lee C-Y
,
Amlie-Wolf A
,
Gangadharan P
,
Mlynarski EE
,
Chou Y-F
,
Lin H-J
,
Issen H
,
Greenfest-Allen E
,
Valladares O
et al.
. 2020.
SparkINFERNO: a scalable high-throughput pipeline for inferring molecular mechanisms of non-coding genetic variants.
.
Bioinformatics. 36(12):3879-3881.
PubMed
T
Ramdhani S
,
Navarro E
,
Udine E
,
Efthymiou AG
,
Schilder BM
,
Parks M
,
Goate A
,
Raj T
. 2020.
Tensor decomposition of stimulated monocyte and macrophage gene expression profiles identifies neurodegenerative disease-specific trans-eQTLs.
.
PLoS Genet. 16(2):e1008549.
PubMed
Katsumata Y
,
Nelson PT
,
Estus S
,
Fardo DW
. 2019.
Translating Alzheimer's disease-associated polymorphisms into functional candidates: a survey of IGAP genes and SNPs.
.
Neurobiol Aging. 74:135-146.
PubMed
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