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Apolipoprotein E4
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2021
Granot-Hershkovitz E
,
Tarraf W
,
Kurniansyah N
,
Daviglus M
,
Isasi CR
,
Kaplan R
,
Lamar M
,
Perreira KM
,
Wassertheil-Smoller S
,
Stickel A
et al.
. 2021.
APOE alleles' association with cognitive function differs across Hispanic/Latino groups and genetic ancestry in the study of Latinos-investigation of neurocognitive aging (HCHS/SOL).
.
Alzheimers Dement. 17(3):466-474.
PubMed
Marca-Ysabel MVictoria
,
Rajabli F
,
Cornejo-Olivas M
,
Whitehead PG
,
Hofmann NK
,
Manrique MZaida Illa
,
Otani DMartin Vel
,
Neyra AKarina Mil
,
Suarez SCastro
,
Vega MMeza
et al.
. 2021.
Dissecting the role of Amerindian genetic ancestry and the ApoE ε4 allele on Alzheimer disease in an admixed Peruvian population.
.
Neurobiol Aging. 101:298.e11-298.e15.
PubMed
Yan Q
,
Nho K
,
Del-Aguila JL
,
Wang X
,
Risacher SL
,
Fan K-H
,
Snitz BE
,
Aizenstein HJ
,
Mathis CA
,
Lopez OL
et al.
. 2021.
Genome-wide association study of brain amyloid deposition as measured by Pittsburgh Compound-B (PiB)-PET imaging.
.
Mol Psychiatry. 26(1):309-321.
PubMed
Fulton-Howard B
,
Goate AM
,
Adelson RP
,
Koppel J
,
Gordon ML
,
Barzilai N
,
Atzmon G
,
Davies P
,
Freudenberg-Hua Y
. 2021.
Greater effect of polygenic risk score for Alzheimer's disease among younger cases who are apolipoprotein E-ε4 carriers.
.
Neurobiol Aging. 99:101.e1-101.e9.
PubMed
Griswold AJ
,
Celis K
,
Bussies PL
,
Rajabli F
,
Whitehead PL
,
Hamilton-Nelson KL
,
Beecham GW
,
Dykxhoorn DM
,
Nuytemans K
,
Wang L
et al.
. 2021.
Increased APOE ε4 expression is associated with the difference in Alzheimer's disease risk from diverse ancestral backgrounds.
.
Alzheimers Dement. 17(7):1179-1188.
PubMed
2020
Davis AA
,
Inman CE
,
Wargel ZM
,
Dube U
,
Freeberg BM
,
Galluppi A
,
Haines JN
,
Dhavale DD
,
Miller R
,
Choudhury FA
et al.
. 2020.
APOE genotype regulates pathology and disease progression in synucleinopathy.
.
Sci Transl Med. 12(529)
PubMed
Belloy ME
,
Napolioni V
,
Han SS
,
Le Guen Y
,
Greicius MD
. 2020.
Association of Klotho-VS Heterozygosity With Risk of Alzheimer Disease in Individuals Who Carry APOE4.
.
JAMA Neurol. 77(7):849-862.
PubMed
Friedberg JS
,
Aytan N
,
Cherry JD
,
Xia W
,
Standring OJ
,
Alvarez VE
,
Nicks R
,
Svirsky S
,
Meng G
,
Jun G
et al.
. 2020.
Associations between brain inflammatory profiles and human neuropathology are altered based on apolipoprotein E ε4 genotype.
.
Sci Rep. 10(1):2924.
PubMed
Reiman EM
,
Arboleda-Velasquez JF
,
Quiroz YT
,
Huentelman MJ
,
Beach TG
,
Caselli RJ
,
Chen Y
,
Su Y
,
Myers AJ
,
Hardy J
et al.
. 2020.
Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study.
.
Nat Commun. 11(1):667.
PubMed
Ibañez L
,
Bahena JA
,
Yang C
,
Dube U
,
Farias FHG
,
Budde JP
,
Bergmann K
,
Brenner-Webster C
,
Morris JC
,
Perrin RJ
et al.
. 2020.
Functional genomic analyses uncover APOE-mediated regulation of brain and cerebrospinal fluid beta-amyloid levels in Parkinson disease.
.
Acta Neuropathol Commun. 8(1):196.
PubMed
Ajnakina O
,
Cadar D
,
Steptoe A
. 2020.
Interplay between Socioeconomic Markers and Polygenic Predisposition on Timing of Dementia Diagnosis.
.
J Am Geriatr Soc. 68(7):1529-1536.
PubMed
Kulick ER
,
Elkind MSV
,
Boehme AK
,
Joyce NR
,
Schupf N
,
Kaufman JD
,
Mayeux R
,
Manly JJ
,
Wellenius GA
. 2020.
Long-term exposure to ambient air pollution, APOE-ε4 status, and cognitive decline in a cohort of older adults in northern Manhattan.
.
Environ Int. 136:105440.
PubMed
2018
Rajabli F
,
Feliciano BE
,
Celis K
,
Hamilton-Nelson KL
,
Whitehead PL
,
Adams LD
,
Bussies PL
,
Manrique CP
,
Rodriguez A
,
Rodriguez V
et al.
. 2018.
Ancestral origin of ApoE ε4 Alzheimer disease risk in Puerto Rican and African American populations.
.
PLoS Genet. 14(12):e1007791.
PubMed
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