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2021
Deters KD
,
Napolioni V
,
Sperling RA
,
Greicius MD
,
Mayeux R
,
Hohman T
,
Mormino EC
. 2021.
Amyloid PET Imaging in Self-Identified Non-Hispanic Black Participants of the Anti-Amyloid in Asymptomatic Alzheimer's Disease (A4) Study.
.
Neurology. 96(11):e1491-e1500.
PubMed
Rizvi B
,
Lao PJ
,
Chesebro AG
,
Dworkin JD
,
Amarante E
,
Beato JM
,
Gutierrez J
,
Zahodne LB
,
Schupf N
,
Manly JJ
et al.
. 2021.
Association of Regional White Matter Hyperintensities With Longitudinal Alzheimer-Like Pattern of Neurodegeneration in Older Adults.
.
JAMA Netw Open. 4(10):e2125166.
PubMed
Andrews SJ
,
Fulton-Howard B
,
O'Reilly P
,
Marcora E
,
Goate AM
. 2021.
Causal Associations Between Modifiable Risk Factors and the Alzheimer's Phenome.
.
Ann Neurol. 89(1):54-65.
PubMed
Patel D
,
Zhang X
,
Farrell JJ
,
Chung J
,
Stein TD
,
Lunetta KL
,
Farrer LA
. 2021.
Cell-type-specific expression quantitative trait loci associated with Alzheimer disease in blood and brain tissue.
.
Transl Psychiatry. 11(1):250.
PubMed
de Erausquin GA
,
Snyder H
,
Carrillo M
,
Hosseini AA
,
Brugha TS
,
Seshadri S
. 2021.
The chronic neuropsychiatric sequelae of COVID-19: The need for a prospective study of viral impact on brain functioning.
.
Alzheimers Dement. 17(6):1056-1065.
PubMed
Patrick E
,
Olah M
,
Taga M
,
Klein H-U
,
Xu J
,
White CC
,
Felsky D
,
Agrawal S
,
Gaiteri C
,
Chibnik LB
et al.
. 2021.
A cortical immune network map identifies distinct microglial transcriptional programs associated with β-amyloid and Tau pathologies.
.
Transl Psychiatry. 11(1):50.
PubMed
Avila JF
,
Rentería MArce
,
Jones RN
,
Vonk JMJ
,
Turney I
,
Sol K
,
Seblova D
,
Arias F
,
Hill-Jarrett T
,
Levy S-A
et al.
. 2021.
Education differentially contributes to cognitive reserve across racial/ethnic groups.
.
Alzheimers Dement. 17(1):70-80.
PubMed
Robins C
,
Liu Y
,
Fan W
,
Duong DM
,
Meigs J
,
Harerimana NV
,
Gerasimov ES
,
Dammer EB
,
Cutler DJ
,
Beach TG
et al.
. 2021.
Genetic control of the human brain proteome.
.
Am J Hum Genet. 108(3):400-410.
PubMed
Yan Q
,
Nho K
,
Del-Aguila JL
,
Wang X
,
Risacher SL
,
Fan K-H
,
Snitz BE
,
Aizenstein HJ
,
Mathis CA
,
Lopez OL
et al.
. 2021.
Genome-wide association study of brain amyloid deposition as measured by Pittsburgh Compound-B (PiB)-PET imaging.
.
Mol Psychiatry. 26(1):309-321.
PubMed
Baird DA
,
Liu JZ
,
Zheng J
,
Sieberts SK
,
Perumal T
,
Elsworth B
,
Richardson TG
,
Chen C-Y
,
Carrasquillo MM
,
Allen M
et al.
. 2021.
Identifying drug targets for neurological and psychiatric disease via genetics and the brain transcriptome.
.
PLoS Genet. 17(1):e1009224.
PubMed
Xu H
,
O'Reilly M
,
Gibbons GS
,
Changolkar L
,
McBride JD
,
Riddle DM
,
Zhang B
,
Stieber A
,
Nirschl J
,
Kim S-J
et al.
. 2021.
In vitro amplification of pathogenic tau conserves disease-specific bioactive characteristics.
.
Acta Neuropathol. 141(2):193-215.
PubMed
Wingo AP
,
Liu Y
,
Gerasimov ES
,
Gockley J
,
Logsdon BA
,
Duong DM
,
Dammer EB
,
Robins C
,
Beach TG
,
Reiman EM
et al.
. 2021.
Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer's disease pathogenesis.
.
Nat Genet. 53(2):143-146.
PubMed
Damotte V
,
van der Lee SJ
,
Chouraki V
,
Grenier-Boley B
,
Simino J
,
Adams H
,
Tosto G
,
White C
,
Terzikhan N
,
Cruchaga C
et al.
. 2021.
Plasma amyloid β levels are driven by genetic variants near APOE, BACE1, APP, PSEN2: A genome-wide association study in over 12,000 non-demented participants.
.
Alzheimers Dement. 17(10):1663-1674.
PubMed
Ramos-Miguel A
,
Jones AA
,
Petyuk VA
,
Barakauskas VE
,
Barr AM
,
Leurgans SE
,
De Jager PL
,
Casaletto KB
,
Schneider JA
,
Bennett DA
et al.
. 2021.
Proteomic identification of select protein variants of the SNARE interactome associated with cognitive reserve in a large community sample.
.
Acta Neuropathol. 141(5):755-770.
PubMed
Patel D
,
Zhang X
,
Farrell JJ
,
Lunetta KL
,
Farrer LA
. 2021.
Set-Based Rare Variant Expression Quantitative Trait Loci in Blood and Brain from Alzheimer Disease Study Participants.
.
Genes (Basel). 12(3)
PubMed
Kim M
,
Bao J
,
Liu K
,
Park B-Y
,
Park H
,
Baik JYoung
,
Shen L
. 2021.
A structural enriched functional network: An application to predict brain cognitive performance.
.
Med Image Anal. 71:102026.
PubMed
Wang M
,
Li A
,
Sekiya M
,
Beckmann ND
,
Quan X
,
Schrode N
,
Fernando MB
,
Yu A
,
Zhu L
,
Cao J
et al.
. 2021.
Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer's Disease.
.
Neuron. 109(2):257-272.e14.
PubMed
2020
Lancour D
,
Dupuis J
,
Mayeux R
,
Haines JL
,
Pericak-Vance MA
,
Schellenberg GC
,
Crovella M
,
Farrer LA
,
Kasif S
. 2020.
Analysis of brain region-specific co-expression networks reveals clustering of established and novel genes associated with Alzheimer disease.
.
Alzheimers Res Ther. 12(1):103.
PubMed
Du L
,
Liu F
,
Liu K
,
Yao X
,
Risacher SL
,
Han J
,
Saykin AJ
,
Shen L
. 2020.
Associating Multi-Modal Brain Imaging Phenotypes and Genetic Risk Factors via a Dirty Multi-Task Learning Method.
.
IEEE Trans Med Imaging. 39(11):3416-3428.
PubMed
Raghavan NS
,
Dumitrescu L
,
Mormino E
,
Mahoney ER
,
Lee AJ
,
Gao Y
,
Bilgel M
,
Goldstein D
,
Harrison T
,
Engelman CD
et al.
. 2020.
Association Between Common Variants in RBFOX1, an RNA-Binding Protein, and Brain Amyloidosis in Early and Preclinical Alzheimer Disease.
.
JAMA Neurol. 77(10):1288-1298.
PubMed
Belloy ME
,
Napolioni V
,
Han SS
,
Le Guen Y
,
Greicius MD
. 2020.
Association of Klotho-VS Heterozygosity With Risk of Alzheimer Disease in Individuals Who Carry APOE4.
.
JAMA Neurol. 77(7):849-862.
PubMed
Friedberg JS
,
Aytan N
,
Cherry JD
,
Xia W
,
Standring OJ
,
Alvarez VE
,
Nicks R
,
Svirsky S
,
Meng G
,
Jun G
et al.
. 2020.
Associations between brain inflammatory profiles and human neuropathology are altered based on apolipoprotein E ε4 genotype.
.
Sci Rep. 10(1):2924.
PubMed
Peng B
,
Yao X
,
Risacher SL
,
Saykin AJ
,
Shen L
,
Ning X
. 2020.
Cognitive biomarker prioritization in Alzheimer's Disease using brain morphometric data.
.
BMC Med Inform Decis Mak. 20(1):319.
PubMed
Armstrong NJ
,
Mather KA
,
Sargurupremraj M
,
Knol MJ
,
Malik R
,
Satizabal CL
,
Yanek LR
,
Wen W
,
Gudnason VG
,
Dueker ND
et al.
. 2020.
Common Genetic Variation Indicates Separate Causes for Periventricular and Deep White Matter Hyperintensities.
.
Stroke. 51(7):2111-2121.
PubMed
Srinivasan D
,
Erus G
,
Doshi J
,
Wolk DA
,
Shou H
,
Habes M
,
Davatzikos C
. 2020.
A comparison of Freesurfer and multi-atlas MUSE for brain anatomy segmentation: Findings about size and age bias, and inter-scanner stability in multi-site aging studies.
.
Neuroimage. 223:117248.
PubMed
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