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2023

2023,  
Neurobiology of Aging

Amyloid and tau pathology are associated with cerebral blood flow in a mixed sample of nondemented older adults with and without vascular risk factors for Alzheimer's disease

Swinford, CG., et al.
2023,  
Statistics in Medicine

Deep causal feature extraction and inference with neuroimaging genetic data

Yao, Y., et al.
2023,  
JAMA neurology

Associations of Sex, Race, and Apolipoprotein E Alleles With Multiple Domains of Cognition Among Older Adults

Walters, S., et al.
2023,  
Alzheimer Disease and Associated Disorders

Visuospatial and Verbal Memory Differences in Amish Individuals With Alzheimer Disease and Related Dementias

Prough, MB., et al.
2023,  
Journal of the American Geriatrics Society

Can virtual reality travel help nursing home patients fulfill their bucket list?

Rodriguez, DK.
2023,  
Nature Reviews. Cardiology

The bidirectional association between atrial fibrillation and myocardial infarction

Frederiksen, TC., et al.
2023,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

The Early-Onset Alzheimer's Disease Whole-Genome Sequencing Project: Study design and methodology

Ray, NR., et al.
2023,  
International Journal of Geriatric Psychiatry

Neuropsychiatric features in a multi-ethnic population with Alzheimer disease and mild cognitive impairment

Celis, K., et al.
2023,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Ancestry-related differences in chromatin accessibility and gene expression of APOE ε4 are associated with Alzheimer's disease risk

Celis, K., et al.
2023,  
Cell Reports

Cell-type-specific regulation of APOE and CLU levels in human neurons by the Alzheimer's disease risk gene SORL1

Lee, H., et al.
2023,  
Cell Reports

Poly(GR) interacts with key stress granule factors promoting its assembly into cytoplasmic inclusions

Park, J., et al.
2023,  
Human Molecular Genetics

Integrating GWAS summary statistics, individual-level genotypic and omic data to enhance the performance for large-scale trait imputation

Ren, J., et al.
2023,  
Journal of Neuropathology and Experimental Neurology

LATE-NC risk alleles (in TMEM106B, GRN, and ABCC9 genes) among persons with African ancestry

Katsumata, Y., et al.
2023,  
Nature Communications

Whole genome deconvolution unveils Alzheimer's resilient epigenetic signature

Berson, E., et al.
2023,  
Proceedings of the National Academy of Sciences of the United States of America

The liquid-to-solid transition of FUS is promoted by the condensate surface

Shen, Y., et al.
2023,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

DNA from multiple viral species is associated with Alzheimer's disease risk

Tejeda, M., et al.
2023,  
Genetic Epidemiology

Inference of causal metabolite networks in the presence of invalid instrumental variables with GWAS summary data

Chen, S., et al.
2023,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Transcriptional risk scores in Alzheimer's disease: From pathology to cognition

Pyun, J., et al.
2023,  
Journal of Clinical Medicine

Genetics of Alzheimer's Disease in the African American Population

Logue, MW., et al.
2023,  
Cell Genomics

Multiset correlation and factor analysis enables exploration of multi-omics data

Brown, BC., et al.
2023,  
Biology of Sex Differences

Sex differences in metabolic phenotype and hypothalamic inflammation in the 3xTg-AD mouse model of Alzheimer's disease

Robison, LS., et al.
2023,  
BMJ open

Using community-based geographical information system (GIS) to recruit older Asian Americans in an Alzheimer's disease study

Lee, H., et al.
2023,  
Neuron

An astrocyte BMAL1-BAG3 axis protects against alpha-synuclein and tau pathology

Sheehan, PW., et al.
2023,  
Bioinformatics (Oxford, England)

ShinyBioHEAT: an interactive shiny app to identify phenotype driver genes in E.coli and B.subtilis

Wang, C., et al.
2023,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Genome-wide methylomic regulation of multiscale gene networks in Alzheimer's disease

Wang, E., et al.
2023,  
Journal of the American Geriatrics Society

Nursing home infection control strategies during the COVID-19 pandemic

Festa, N., et al.
2023,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Identification of circRNAs linked to Alzheimer's disease and related dementias

Puri, S., et al.
2023,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Obesity impacts the expression of Alzheimer's disease-related genes: The Framingham Heart Study

Charisis, S., et al.
2023,  
International Journal of Stroke: Official Journal of the International Stroke Society

Pleiotropy analysis between lobar intracerebral hemorrhage and CSF β-amyloid highlights new and established associations

Marini, S., et al.
2023,  
Human Molecular Genetics

Human herpesvirus 8 ORF57 protein is able to reduce TDP-43 pathology: network analysis identifies interacting pathways

Webber, CJ., et al.
2023,  
Proceedings of the National Academy of Sciences of the United States of America

Slingshot homolog-1-mediated Nrf2 sequestration tips the balance from neuroprotection to neurodegeneration in Alzheimer's disease

Cazzaro, S., et al.
2023,  
medRxiv: The Preprint Server for Health Sciences

APOE loss-of-function variants: Compatible with longevity and associated with resistance to Alzheimer's Disease pathology

Chemparathy, A., et al.
2023,  
Journal of Neuropathology and Experimental Neurology

The frequency and distribution of TDP-43 pathology in argyrophilic grain disease

Koga, S., et al.
2023,  
Human Molecular Genetics

Genetic architecture of plasma Alzheimer disease biomarkers

Bradley, J., et al.
2023,  
Science Translational Medicine

Proteomics analysis of plasma from middle-aged adults identifies protein markers of dementia risk in later life

Walker, KA., et al.
2023,  
HGG advances

Using GWAS summary data to impute traits for genotyped individuals

Ren, J., et al.
2023,  
HGG advances

Admixture mapping implicates 13q33.3 as ancestry-of-origin locus for Alzheimer disease in Hispanic and Latino populations

Horimoto, ARVR., et al.
2023,  
Cell Metabolism

When a calorie is not just a calorie: Diet quality and timing as mediators of metabolism and healthy aging

Mihaylova, MM., et al.
2023,  
NPJ Regenerative medicine

Nerve growth factor receptor (Ngfr) induces neurogenic plasticity by suppressing reactive astroglial Lcn2/Slc22a17 signaling in Alzheimer's disease

Siddiqui, T., et al.
2023,  
NPJ Parkinson's disease

Proteome wide association studies of LRRK2 variants identify novel causal and druggable proteins for Parkinson's disease

Phillips, B., et al.
2023,  
Acta Neuropathologica Communications

Diffuse argyrophilic grain disease with TDP-43 proteinopathy and neuronal intermediate filament inclusion disease: FTLD with mixed tau, TDP-43 and FUS pathologies

Koga, S., et al.
2023,  
Science Translational Medicine

Proteomics of brain, CSF, and plasma identifies molecular signatures for distinguishing sporadic and genetic Alzheimer's disease

Sung, YJ., et al.
2023,  
Brain: A Journal of Neurology

Reduced endothelial caveolin-1 underlies deficits in brain insulin signalling in type 2 diabetes

Shetti, AU., et al.
2023,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Long-term blood pressure patterns in midlife and dementia in later life: Findings from the Framingham Heart Study

Kim, H., et al.
2023,  
International Journal of Molecular Sciences

Stealth Liposomes Encapsulating a Potent ACAT1/SOAT1 Inhibitor F12511: Pharmacokinetic, Biodistribution, and Toxicity Studies in Wild-Type Mice and Efficacy Studies in Triple Transgenic Alzheimer's Disease Mice

De La Torre, AL., et al.
2023,  
NeuroImage

Image harmonization: A review of statistical and deep learning methods for removing batch effects and evaluation metrics for effective harmonization

Hu, F., et al.
2023,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Examination of potentially modifiable dementia risk factors across the adult life course: The Framingham Heart Study

Hwang, PH., et al.
2023,  
Behavior Genetics

A Varying Coefficient Model to Jointly Test Genetic and Gene-Environment Interaction Effects

Zhou, Z., et al.
2023,  
Acta Neuropathologica

Brain DNA methylomic analysis of frontotemporal lobar degeneration reveals OTUD4 in shared dysregulated signatures across pathological subtypes

Fodder, K., et al.
2023,  
Circulation. Cardiovascular Quality and Outcomes

Association Between Electrocardiographic Age and Cardiovascular Events in Community Settings: The Framingham Heart Study

Brant, LCC., et al.
2023,  
Nature Human Behaviour

Identifying modifiable factors and their joint effect on dementia risk in the UK Biobank

Zhang, Y., et al.
2023,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Identification of novel genes for age-at-onset of Alzheimer's disease by combining quantitative and survival trait analyses

Li, Y., et al.
2023,  
Otolaryngology--Head and Neck Surgery: Official Journal of American Academy of Otolaryngology-Head and Neck Surgery

Association of Central Auditory Processing Dysfunction With Preclinical Alzheimer's Disease

Byun, MS., et al.
2023,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Prevalence of dementia in India: National and state estimates from a nationwide study

Lee, J., et al.
2023,  
Nature Medicine

Clonal hematopoiesis is associated with protection from Alzheimer's disease

Bouzid, H., et al.
2023,  
Scientific Reports

Modeling of mitochondrial genetic polymorphisms reveals induction of heteroplasmy by pleiotropic disease locus 10398A>G

Smullen, M., et al.
2023,  
Molecular Neurodegeneration

A genome-wide search for pleiotropy in more than 100,000 harmonized longitudinal cognitive domain scores

Kang, M., et al.
2023,  
International Journal of Molecular Sciences

Cholesterol, Amyloid Beta, Fructose, and LPS Influence ROS and ATP Concentrations and the Phagocytic Capacity of HMC3 Human Microglia Cell Line

Muñoz Herrera, OM., et al.
2023,  
Nature Communications

Leveraging football accelerometer data to quantify associations between repetitive head impacts and chronic traumatic encephalopathy in males

Daneshvar, DH., et al.
2023,  
British Journal of Pharmacology

Hydrogen sulfide signalling in neurodegenerative diseases

Tripathi, SJ., et al.
2023,  
The Journal of Clinical Investigation

Complement C3aR depletion reverses HIF-1α-induced metabolic impairment and enhances microglial response to Aβ pathology

Gedam, M., et al.
2023,  
Alzheimer's Research & Therapy

Body mass index and two-year change of in vivo Alzheimer's disease pathologies in cognitively normal older adults

Lee, S., et al.
2023,  
GeroScience

Sexual dimorphic metabolic and cognitive responses of C57BL/6 mice to Fisetin or Dasatinib and quercetin cocktail oral treatment

Fang, Y., et al.
2023,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Profiling and predicting distinct tau progression patterns: An unsupervised data-driven approach to flortaucipir positron emission tomography

Tosun, D., et al.
2023,  
Neurology

The Importance of Understanding Neighborhood Environments in Neurology Care

Kobau, R.
2023,  
Angewandte Chemie (International Ed. in English)

Apolipoprotein E Recognizes Alzheimer's Disease Associated 3-O Sulfation of Heparan Sulfate

Mah, D., et al.
2023,  
The Journal of Cell Biology

Autolysosomal exocytosis of lipids protect neurons from ferroptosis

Ralhan, I., et al.
2023,  
Neurobiology of Disease

Amyloid beta peptides (Aβ) from Alzheimer's disease neuronal secretome induce endothelial activation in a human cerebral microvessel model

Shin, YJ., et al.
2023,  
The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences

Chronic, Mild Hypothermic Environmental Temperature Does Not Ameliorate Cognitive Deficits in an Alzheimer's Disease Mouse

McFadden, S., et al.
2023,  
Brain: A Journal of Neurology

The pathotome and precision health

Younes, K.
2023,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Novel loci for Alzheimer's disease identified by a genome-wide association study in Ashkenazi Jews

Li, D., et al.
2023,  
Aging and Disease

Serum Adiponectin and In Vivo Brain Amyloid Deposition in Cognitively Normal Older Adults: A Cohort Study

Kim, JW., et al.
2023,  
Telemedicine Journal and E-Health: The Official Journal of the American Telemedicine Association

Decreasing Racial Disparities in Preventable Emergency Department Visits Through Hospital Health Information Technology Patient Engagement Functionalities

Wang, N.
2023,  
Nature Neuroscience

Single-nucleus multiregion transcriptomic analysis of brain vasculature in Alzheimer's disease

Sun, N., et al.
2023,  
GeroScience

Geroprotective interventions in the 3xTg mouse model of Alzheimer's disease

Sonsalla, MM.
2023,  
Journal of the American Geriatrics Society

Factors affecting the recruitment of Hispanic/Latinx American older adults in clinical trials in the United States: A scoping review

Rodriguez, DK., et al.
2023,  
Nature Aging

Targeting the biology of aging with mTOR inhibitors

Mannick, JB.
2023,  
Neurobiology of Aging

Characterization of apathy-like behaviors in the 5xFAD mouse model of Alzheimer's disease

Keszycki, R., et al.
2023,  
The Journal of Physiology

Regulation of metabolic health by dietary histidine in mice

Flores, V., et al.
2023,  
British Journal of Cancer

Evolution of cisplatin resistance through coordinated metabolic reprogramming of the cellular reductive state

Yu, W., et al.
2023,  
Journal of Biomedical Informatics

HLA amino acid Mismatch-Based risk stratification of kidney allograft failure using a novel Machine learning algorithm

Dasariraju, S., et al.
2023,  
Acta Neuropathologica

Defects in lysosomal function and lipid metabolism in human microglia harboring a TREM2 loss of function mutation

Filipello, F., et al.
2023,  
Trends in Neurosciences

Moving beyond amyloid and tau to capture the biological heterogeneity of Alzheimer's disease

Young-Pearse, TL., et al.
2023,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

APOE and immunity: Research highlights

Kloske, CM., et al.
2023,  
Neurobiology of Aging

Multi-omic characterization of brain changes in the vascular endothelial growth factor family during aging and Alzheimer's disease

Seto, M., et al.
2023,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Social enrichment on the job: Complex work with people improves episodic memory, promotes brain reserve, and reduces the risk of dementia

Coleman, ME., et al.
2023,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Admixture mapping identifies novel Alzheimer's disease risk regions in African Americans

Rajabli, F., et al.
2023,  
Journal of Racial and Ethnic Health Disparities

Multiple Chronic Conditions and Disability among Vietnamese Older Adults: Results from the Vietnamese Aging and Care Survey (VACS)

Miyawaki, CE., et al.
2023,  
Science Advances

Increased 3-O-sulfated heparan sulfate in Alzheimer's disease brain is associated with genetic risk gene HS3ST1

Wang, Z., et al.
2023,  
Translational Psychiatry

Circulating S100B levels at birth and risk of six major neuropsychiatric or neurological disorders: a two-sample Mendelian Randomization Study

Pan, M., et al.
2023,  
Cancers

Genetic Variants Associated with Longitudinal Cognitive Performance in Older Breast Cancer Patients and Controls

Nudelman, K., et al.
2023,  
Biology of Sex Differences

Menopause causes metabolic and cognitive impairments in a chronic cerebral hypoperfusion model of vascular contributions to cognitive impairment and dementia

Gannon, OJ., et al.
2023,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Large-scale proteome and metabolome analysis of CSF implicates altered glucose and carbon metabolism and succinylcarnitine in Alzheimer's disease

Panyard, DJ., et al.
2023,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Leveraging African American family connectors for Alzheimer's disease genomic studies

Byfield, G., et al.
2023,  
Biology of Sex Differences

Sex differences in the effects of high fat diet on underlying neuropathology in a mouse model of VCID

Abi-Ghanem, C., et al.
2023,  
Neuropathology: Official Journal of the Japanese Society of Neuropathology

Comments on an autopsy case of progressive supranuclear palsy treated with monoclonal antibody against tau

Koga, S., et al.
2023,  
Scientific Reports

Transcriptomic and glycomic analyses highlight pathway-specific glycosylation alterations unique to Alzheimer's disease

Tang, X., et al.
2023,  
Antioxidants (Basel, Switzerland)

Protective Roles of Hydrogen Sulfide in Alzheimer's Disease and Traumatic Brain Injury

Paul, BD.
2023,  
Nature Communications

Functional variants identify sex-specific genes and pathways in Alzheimer's Disease

Bourquard, T., et al.
2023,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Alzheimer's disease heterogeneity explained by polygenic risk scores derived from brain transcriptomic profiles

Chung, J., et al.

2022

2022,  
EClinicalMedicine

Different loneliness types, cognitive function, and brain structure in midlife: Findings from the Framingham Heart Study

Tao, Q., et al.
2022,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Metabolomic and lipidomic signatures in autosomal dominant and late-onset Alzheimer's disease brains

Novotny, BC., et al.
2022,  
Human Genetics

Genome interpretation using in silico predictors of variant impact

Katsonis, P., et al.
2022,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

The National Institute on Aging Late-Onset Alzheimer's Disease Family Based Study: A resource for genetic discovery

Reyes-Dumeyer, D., et al.
2022,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Identifying differential regulatory control of APOE ɛ4 on African versus European haplotypes as potential therapeutic targets

Nuytemans, K., et al.
2022,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Integration of GWAS and brain transcriptomic analyses in a multiethnic sample of 35,245 older adults identifies DCDC2 gene as predictor of episodic memory maintenance

Gao, Y., et al.
2022,  
Neurology. Genetics

A Fast and Robust Strategy to Remove Variant-Level Artifacts in Alzheimer Disease Sequencing Project Data

Belloy, ME., et al.
2022,  
Nature

Stroke genetics informs drug discovery and risk prediction across ancestries

Mishra, A., et al.
2022,  
BMC bioinformatics

Deep multiview learning to identify imaging-driven subtypes in mild cognitive impairment

Feng, Y., et al.
2022,  
Human Molecular Genetics

Genotype-phenotype correlation of T-cell subtypes reveals senescent and cytotoxic genes in Alzheimer's disease

Dressman, D., et al.
2022,  
BMC bioinformatics

Identifying genes associated with brain volumetric differences through tissue specific transcriptomic inference from GWAS summary data

Mai, H., et al.
2022,  
Neurogenetics

Whole-exome sequencing reveals PSEN1 and ATP7B combined variants as a possible cause of early-onset Lewy body dementia: a case study of genotype-phenotype correlation

Tábuas-Pereira, M., et al.
2022,  
Alzheimer's Research & Therapy

Distinct sex-specific DNA methylation differences in Alzheimer's disease

C Silva, T., et al.
2022,  
Human Genetics

The promise of automated machine learning for the genetic analysis of complex traits

Manduchi, E., et al.
2022,  
The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences

Association Between Mediterranean Diet and Functional Status in Older Adults: A Longitudinal Study Based on the Washington Heights-Inwood Columbia Aging Project

Guo, J., et al.
2022,  
Trends in genetics: TIG

'Fly-ing' from rare to common neurodegenerative disease mechanisms

Ma, M., et al.
2022,  
Neurobiology of Aging

Amyloid, cerebrovascular disease, and neurodegeneration biomarkers are associated with cognitive trajectories in a racially and ethnically diverse, community-based sample

Lao, PJ., et al.
2022,  
Human Molecular Genetics

Genetic architecture of RNA editing regulation in Alzheimer's disease across diverse ancestral populations

Gardner, OK., et al.
2022,  
Genes

Mining High-Level Imaging Genetic Associations via Clustering AD Candidate Variants with Similar Brain Association Patterns

Wu, R., et al.
2022,  
Proceedings of the National Academy of Sciences of the United States of America

Astrocyte-secreted glypican-4 drives APOE4-dependent tau hyperphosphorylation

Saroja, SR., et al.
2022,  
Science (New York, N.Y.)

Functional regulatory variants implicate distinct transcriptional networks in dementia

Cooper, YA., et al.
2022,  
Bioinformatics (Oxford, England)

Omnibus and Robust Deconvolution Scheme for Bulk RNA Sequencing Data Integrating Multiple Single-Cell Reference Sets and Prior Biological Knowledge

Chen, C., et al.
2022,  
Nature Communications

Cross-tissue analysis of blood and brain epigenome-wide association studies in Alzheimer's disease

C Silva, T., et al.
2022,  
Molecular Psychiatry

Genome-wide meta-analyses reveal novel loci for verbal short-term memory and learning

Lahti, J., et al.
2022,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Differential diagnosis of amnestic dementia patients based on an FDG-PET signature of autopsy-confirmed LATE-NC

Grothe, MJ., et al.
2022,  
Human Molecular Genetics

Scalable approaches for functional analyses of whole-genome sequencing non-coding variants

Kuksa, PP., et al.
2022,  
Brain: A Journal of Neurology

Epigenetic and integrative cross-omics analyses of cerebral white matter hyperintensities on MRI

Yang, Y., et al.
2022,  
Neuropsychology

Cognitive domain harmonization and cocalibration in studies of older adults

Mukherjee, S., et al.
2022,  
BMC medical genomics

Identifying genetic markers enriched by brain imaging endophenotypes in Alzheimer's disease

Kim, M., et al.
2022,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Plasma p-tau181 shows stronger network association to Alzheimer's disease dementia than neurofilament light and total tau

Frank, B., et al.
2022,  
Journal of Cerebral Blood Flow and Metabolism: Official Journal of the International Society of Cerebral Blood Flow and Metabolism

Genome-wide association study of brain arteriolosclerosis

Shade, LM., et al.
2022,  
Journal of Alzheimer's disease: JAD

The Advisory Group on Risk Evidence Education for Dementia: Multidisciplinary and Open to All

Rosen, AC., et al.
2022,  
Brain: A Journal of Neurology

Sex differences in the genetic architecture of cognitive resilience to Alzheimer's disease

Eissman, JM., et al.
2022,  
Translational Psychiatry

Polygenic resilience scores capture protective genetic effects for Alzheimer's disease

Hou, J., et al.
2022,  
Human Molecular Genetics

Accounting for nonlinear effects of gene expression identifies additional associated genes in transcriptome-wide association studies

Lin, Z., et al.
2022,  
Cells

A Method for Bridging Population-Specific Genotypes to Detect Gene Modules Associated with Alzheimer's Disease

Dai, Y., et al.
2022,  
HGG advances

The genetic architecture of Alzheimer disease risk in the Ohio and Indiana Amish

Osterman, MD., et al.
2022,  
Nucleic Acids Research

EPIMUTESTR: a nearest neighbor machine learning approach to predict cancer driver genes from the evolutionary action of coding variants

Parvandeh, S., et al.
2022,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Contribution of Alzheimer's biomarkers and risk factors to cognitive impairment and decline across the Alzheimer's disease continuum

Tosun, D., et al.
2022,  
JAMA neurology

Association of Rare APOE Missense Variants V236E and R251G With Risk of Alzheimer Disease

Le Guen, Y., et al.
2022,  
Acta Neuropathologica

FMNL2 regulates gliovascular interactions and is associated with vascular risk factors and cerebrovascular pathology in Alzheimer's disease

Lee, AJ., et al.
2022,  
Stem Cell Research

Generation of two iPSC lines (UMi038-A & UMi039-A) from siblings bearing an Alzheimer's disease-associated variant in SORL1

DeRosa, BA., et al.
2022,  
Annals of Neurology

Association of Apolipoprotein E ɛ4 Allele with Enlarged Perivascular Spaces

Pinheiro, A., et al.
2022,  
Brain: A Journal of Neurology

Gene-mapping study of extremes of cerebral small vessel disease reveals TRIM47 as a strong candidate

Mishra, A., et al.
2022,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Genome-wide association and multi-omics studies identify MGMT as a novel risk gene for Alzheimer's disease among women

Chung, J., et al.
2022,  
Genetic Epidemiology

Statistical power of transcriptome-wide association studies

He, R., et al.
2022,  
Biological Psychiatry

Integrative Co-methylation Network Analysis Identifies Novel DNA Methylation Signatures and Their Target Genes in Alzheimer's Disease

Kim, JP., et al.
2022,  
Cell

Cholesterol and matrisome pathways dysregulated in astrocytes and microglia

Tcw, J., et al.
2022,  
BMC genomics

Integrative analysis of summary data from GWAS and eQTL studies implicates genes differentially expressed in Alzheimer's disease

Lee, B., et al.
2022,  
American Journal of Human Genetics

Integration of rare expression outlier-associated variants improves polygenic risk prediction

Smail, C., et al.
2022,  
Molecular Psychiatry

Admixture Mapping of Alzheimer's disease in Caribbean Hispanics identifies a new locus on 22q13.1

Kizil, C., et al.
2022,  
Nature Protocols

Chromatin accessibility profiling by ATAC-seq

Grandi, FC., et al.
2022,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Integrative metabolomics-genomics approach reveals key metabolic pathways and regulators of Alzheimer's disease

Horgusluoglu, E., et al.
2022,  
Biological Psychiatry. Cognitive Neuroscience and Neuroimaging

Genomic Studies Across the Lifespan Point to Early Mechanisms Determining Subcortical Volumes

Le Grand, Q., et al.
2022,  
Aging Cell

Alzheimer's disease associated AKAP9 I2558M mutation alters posttranslational modification and interactome of tau and cellular functions in CRISPR-edited human neuronal cells

You, Y., et al.
2022,  
Cells

Single Cell/Nucleus Transcriptomics Comparison in Zebrafish and Humans Reveals Common and Distinct Molecular Responses to Alzheimer's Disease

Cosacak, MI., et al.
2022,  
Neurology

Genetic Risk, Midlife Life's Simple 7, and Incident Dementia in the Atherosclerosis Risk in Communities Study

Tin, A., et al.
2022,  
Nucleic Acids Research

MethReg: estimating the regulatory potential of DNA methylation in gene transcription

Silva, TC., et al.
2022,  
Scientific Reports

Genome-wide association of polygenic risk extremes for Alzheimer's disease in the UK Biobank

Gouveia, C., et al.
2022,  
Journal of Neuroinflammation

High-fat diet exacerbates cognitive decline in mouse models of Alzheimer's disease and mixed dementia in a sex-dependent manner

Gannon, OJ., et al.
2022,  
Brain: A Journal of Neurology

Antemortem plasma phosphorylated tau (181) predicts Alzheimer's disease neuropathology and regional tau at autopsy

Morrison, MS., et al.
2022,  
JAMA psychiatry

Characterizing Heterogeneity in Neuroimaging, Cognition, Clinical Symptoms, and Genetics Among Patients With Late-Life Depression

Wen, J., et al.
2022,  
Genome Research

A general calculus of fitness landscapes finds genes under selection in cancers

Hsu, T., et al.
2022,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Genetic variants in the SHISA6 gene are associated with delayed cognitive impairment in two family datasets

Ramos, J., et al.
2022,  
European Journal of Neurology

Rare variants in TP73 in a frontotemporal dementia cohort link this gene with primary progressive aphasia phenotypes

Tábuas-Pereira, M., et al.
2022,  
Current Protocols

Molecular Quantitative Trait Locus Mapping in Human Complex Diseases

Olayinka, OA., et al.
2022,  
Current Protocols

Molecular Quantitative Trait Locus Mapping in Human Complex Diseases

Olayinka, OA., et al.
2022,  
Annals of Clinical and Translational Neurology

Correlation of plasma and neuroimaging biomarkers in Alzheimer's disease

Brickman, AM., et al.
2022,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Current directions in tau research: Highlights from Tau 2020

Sexton, C., et al.
2022,  
Cells

Identifying Blood Biomarkers for Dementia Using Machine Learning Methods in the Framingham Heart Study

Lin, H., et al.
2022,  
Neurology

Multiple Cortical to Striatal Accumulation Trajectories of β-Amyloid: Do All Roads Lead to Rome?

Vogel, JW.
2022,  
Neuron

ApoE Cascade Hypothesis in the pathogenesis of Alzheimer's disease and related dementias

Martens, YA., et al.
2022,  
Journal of Medical Internet Research

Associations Between the Digital Clock Drawing Test and Brain Volume: Large Community-Based Prospective Cohort (Framingham Heart Study)

Yuan, J., et al.
2022,  
Scientific Reports

Manifestations of Alzheimer's disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90

Heath, L., et al.
2022,  
Med (New York, N.Y.)

Integrating functional genomics with genetics to understand the biology of ALS and FTD

Cruchaga, C.
2022,  
Communications Biology

Meta-analysis of genome-wide association studies identifies ancestry-specific associations underlying circulating total tau levels

Sarnowski, C., et al.
2022,  
American Journal of Human Genetics

Family history aggregation unit-based tests to detect rare genetic variant associations with application to the Framingham Heart Study

Wang, Y., et al.
2022,  
Circulation

Circulating Metabolome and White Matter Hyperintensities in Women and Men

Sliz, E., et al.
2022,  
Neurobiology of Disease

Soluble TREM2: Innocent bystander or active player in neurological diseases?

Filipello, F., et al.
2022,  
Journal of the International Neuropsychological Society: JINS

Midlife Vascular Factors and Prevalence of Mild Cognitive Impairment in Late-Life in Mexico

Arce Rentería, M., et al.
2022,  
Nature Genetics

New insights into the genetic etiology of Alzheimer's disease and related dementias

Bellenguez, C., et al.
2022,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Replication study of AD-associated rare variants

Neupane, A., et al.
2022,  
Genome Research

An association test of the spatial distribution of rare missense variants within protein structures identifies Alzheimer's disease-related patterns

Jin, B., et al.
2022,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Midlife lipid and glucose levels are associated with Alzheimer's disease

Zhang, X., et al.
2022,  
Briefings in Bioinformatics

Deep learning-based identification of genetic variants: application to Alzheimer's disease classification

Jo, T., et al.
2022,  
Acta Neuropathologica Communications

Circular RNA detection identifies circPSEN1 alterations in brain specific to autosomal dominant Alzheimer's disease

Chen, H., et al.
2022,  
NeuroImage

Deep learning for Alzheimer's disease: Mapping large-scale histological tau protein for neuroimaging biomarker validation

Ushizima, D., et al.
2022,  
NAR genomics and bioinformatics

FILER: a framework for harmonizing and querying large-scale functional genomics knowledge

Kuksa, PP., et al.
2022,  
Journal of magnetic resonance imaging: JMRI

Deep Generative Medical Image Harmonization for Improving Cross-Site Generalization in Deep Learning Predictors

Bashyam, VM., et al.
2022,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Progranulin mutations in clinical and neuropathological Alzheimer's disease

Vardarajan, BN., et al.
2022,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Neuropathological lesions and their contribution to dementia and cognitive impairment in a heterogeneous clinical population

Godrich, D., et al.
2022,  
Alzheimer's Research & Therapy

Blood and brain transcriptome analysis reveals APOE genotype-mediated and immune-related pathways involved in Alzheimer disease

Panitch, R., et al.
2022,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Protein phosphatase 2A and complement component 4 are linked to the protective effect of APOE ɛ2 for Alzheimer's disease

Jun, GR., et al.
2022,  
Social Science & Medicine (1982)

Longitudinal associations between racial discrimination and hippocampal and white matter hyperintensity volumes among older Black adults

Zahodne, LB., et al.
2022,  
Alzheimer's Research & Therapy

Challenges at the APOE locus: a robust quality control approach for accurate APOE genotyping

Belloy, ME., et al.
2022,  
Medical Image Analysis

Embracing the disharmony in medical imaging: A Simple and effective framework for domain adaptation

Wang, R., et al.
2022,  
Aging Cell

Aging-related cell type-specific pathophysiologic immune responses that exacerbate disease severity in aged COVID-19 patients

Hou, Y., et al.
2022,  
Current Opinion in Structural Biology

Interpretable artificial intelligence and exascale molecular dynamics simulations to reveal kinetics: Applications to Alzheimer's disease

Martin, W., et al.
2022,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Association of mitochondrial variants and haplogroups identified by whole exome sequencing with Alzheimer's disease

Zhang, X., et al.
2022,  
Neurology. Genetics

Confirming Pathogenicity of the F386L PSEN1 Variant in a South Asian Family With Early-Onset Alzheimer Disease

Eger, SJ., et al.
2022,  
Genetic Epidemiology

Precisely modeling zero-inflated count phenotype for rare variants

Fan, Q., et al.
2022,  
Neurobiology of Aging

Cognitive reserve proxies, Alzheimer pathologies, and cognition

Ko, K., et al.
2022,  
Molecular Neurodegeneration

Murine roseolovirus does not accelerate amyloid-β pathology and human roseoloviruses are not over-represented in Alzheimer disease brains

Bigley, TM., et al.
2022,  
Biomedicines

Phenotypic Heterogeneity among GBA p.R202X Carriers in Lewy Body Spectrum Disorders

Napolioni, V., et al.
2022,  
Molecular Neurodegeneration

Challenge accepted: uncovering the role of rare genetic variants in Alzheimer's disease

Khani, M., et al.
2022,  
Neurology

Predictors of Incident Mild Cognitive Impairment and Its Course in a Diverse Community-Based Population

Angevaare, MJ., et al.
2022,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

The National Institute on Aging Late-Onset Alzheimer's Disease Family Based Study: A resource for genetic discovery

Reyes-Dumeyer, D., et al.
2022,  
Human Brain Mapping

Subcortical volumes across the lifespan: Data from 18,605 healthy individuals aged 3-90 years

Dima, D., et al.
2022,  
Nature Genetics

Genetic analysis of the human microglial transcriptome across brain regions, aging and disease pathologies

Lopes, KdP., et al.
2022,  
Human Brain Mapping

Cortical thickness across the lifespan: Data from 17,075 healthy individuals aged 3-90 years

Frangou, S., et al.
2022,  
Acta Neuropathologica

Genome-wide association study and functional validation implicates JADE1 in tauopathy

Farrell, K., et al.
2022,  
Frontiers in Neurology

Exome Sequencing of a Portuguese Cohort of Frontotemporal Dementia Patients: Looking Into the ALS-FTD Continuum

Tábuas-Pereira, M., et al.
2022,  
Brain Communications

Disentangling Alzheimer's disease neurodegeneration from typical brain ageing using machine learning

Hwang, G., et al.
2022,  
Frontiers in Psychiatry

Associations of digital neuro-signatures with molecular and neuroimaging measures of brain resilience: The altoida large cohort study

Seixas, AA., et al.
2022,  
Journal of Alzheimer's disease: JAD

Measuring Subjective Cognitive Decline in Older Adults: Harmonization Between the Cognitive Change Index and the Measurement of Everyday Cognition Instruments

Wells, LF., et al.
2022,  
Journal of Alzheimer's disease: JAD

Late-Life Physical Activities Moderate the Relationship of Amyloid-β Pathology with Neurodegeneration in Individuals Without Dementia

Sohn, BK., et al.
2022,  
Journal of Alzheimer's disease: JAD

Functional Neural Correlates of Semantic Fluency Task Performance in Mild Cognitive Impairment and Alzheimer's Disease: An FDG-PET Study

Ahn, H., et al.

2021

2021,  
Proceedings of the National Academy of Sciences of the United States of America

Neuronal ROS-induced glial lipid droplet formation is altered by loss of Alzheimer's disease-associated genes

Moulton, MJ., et al.
2021,  
Translational Psychiatry

Genetically regulated expression in late-onset Alzheimer's disease implicates risk genes within known and novel loci

Chen, H., et al.
2021,  
Translational Psychiatry

Association of low-frequency and rare coding variants with information processing speed

Bressler, J., et al.
2021,  
American Journal of Human Genetics

Genome-wide analysis of common and rare variants via multiple knockoffs at biobank scale, with an application to Alzheimer disease genetics

He, Z., et al.
2021,  
Alzheimer's Research & Therapy

Serum zinc levels and in vivo beta-amyloid deposition in the human brain

Kim, JW., et al.
2021,  
Translational Psychiatry

A missense variant in SHARPIN mediates Alzheimer's disease-specific brain damages

Park, JY., et al.
2021,  
Alzheimer's Research & Therapy

Dysregulated expression levels of APH1B in peripheral blood are associated with brain atrophy and amyloid-β deposition in Alzheimer's disease

Park, YH., et al.
2021,  
European journal of human genetics: EJHG

Exploiting family history in aggregation unit-based genetic association tests

Wang, Y., et al.
2021,  
Alzheimer's Research & Therapy

BMI1 is associated with CS8F amyloid-β and rates of cognitive decline in Alzheimer's disease

Kim, JP., et al.
2021,  
JAMA network open

Association of Regional White Matter Hyperintensities With Longitudinal Alzheimer-Like Pattern of Neurodegeneration in Older Adults

Rizvi, B., et al.
2021,  
Molecular Psychiatry

Genome-wide association identifies the first risk loci for psychosis in Alzheimer disease

DeMichele-Sweet, MAA., et al.
2021,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Plasma amyloid β levels are driven by genetic variants near APOE, BACE1, APP, PSEN2: A genome-wide association study in over 12,000 non-demented participants

Damotte, V., et al.
2021,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Dementia in Africa: Current evidence, knowledge gaps, and future directions

Akinyemi, RO., et al.
2021,  
Annals of Neurology

Polygenic Risk Score for Alzheimer's Disease in Caribbean Hispanics

Sariya, S., et al.
2021,  
PLoS genetics

Rare variants in the endocytic pathway are associated with Alzheimer's disease, its related phenotypes, and functional consequences

Zhan, L., et al.
2021,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Midlife vascular risk factors and risk of incident dementia: Longitudinal cohort and Mendelian randomization analyses in the UK Biobank

Malik, R., et al.
2021,  
Journal of the International Neuropsychological Society: JINS

Midlife Vascular Factors and Prevalence of Mild Cognitive Impairment in Late-Life in Mexico

Arce Rentería, M., et al.
2021,  
Neurobiology of Aging

Linkage of Alzheimer disease families with Puerto Rican ancestry identifies a chromosome 9 locus

Rajabli, F., et al.
2021,  
Translational Psychiatry

Heterogeneous effects of genetic risk for Alzheimer's disease on the phenome

Wu, HM., et al.
2021,  
Alzheimer's Research & Therapy

Admixture mapping reveals the association between Native American ancestry at 3q13.11 and reduced risk of Alzheimer's disease in Caribbean Hispanics

Horimoto, ARVR., et al.
2021,  
Medical Image Analysis

A structural enriched functional network: An application to predict brain cognitive performance

Kim, M., et al.
2021,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Increased APOE ε4 expression is associated with the difference in Alzheimer's disease risk from diverse ancestral backgrounds

Griswold, AJ., et al.
2021,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Association of mitochondrial variants and haplogroups identified by whole exome sequencing with Alzheimer's disease

Zhang, X., et al.
2021,  
Nature Communications

Common variants in Alzheimer's disease and risk stratification by polygenic risk scores

de Rojas, I., et al.
2021,  
Journal of Genetic Counseling

Genetic counseling for early onset and familial dementia: Patient perspectives on exome sequencing

Rolf, B., et al.
2021,  
Neurobiology of Disease

Deconstructing the epigenomic architecture of human neurodegeneration

De Jager, PL.
2021,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

The chronic neuropsychiatric sequelae of COVID-19: The need for a prospective study of viral impact on brain functioning

de Erausquin, GA., et al.
2021,  
Stroke

Autonomic Imbalance and Risk of Dementia and Stroke: The Framingham Study

Weinstein, G., et al.
2021,  
The European Journal of Neuroscience

Lifelong chronic psychosocial stress induces a proteomic signature of Alzheimer's disease in wildtype mice

Lyons, CE., et al.
2021,  
Nature Communications

Identification of putative causal loci in whole-genome sequencing data via knockoff statistics

He, Z., et al.
2021,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Social network characteristics moderate associations between cortical thickness and cognitive functioning in older adults

Sharifian, N., et al.
2021,  
Neurobiology of Aging

Dissecting the role of Amerindian genetic ancestry and the ApoE ε4 allele on Alzheimer disease in an admixed Peruvian population

Marca-Ysabel, MV., et al.
2021,  
Acta Neuropathologica

Proteomic identification of select protein variants of the SNARE interactome associated with cognitive reserve in a large community sample

Ramos-Miguel, A., et al.
2021,  
Translational Psychiatry

Cell-type-specific expression quantitative trait loci associated with Alzheimer disease in blood and brain tissue

Patel, D., et al.
2021,  
Acta Neuropathologica Communications

Sex-specific DNA methylation differences in Alzheimer's disease pathology

Zhang, L., et al.
2021,  
Journal of Neuropathology and Experimental Neurology

Asymmetry of Hippocampal Tau Pathology in Primary Age-Related Tauopathy and Alzheimer Disease

Walker, JM., et al.
2021,  
Aging

Multiomics integrative analysis identifies APOE allele-specific blood biomarkers associated to Alzheimer's disease etiopathogenesis

Madrid, L., et al.
2021,  
Genetic Epidemiology

An exploration of genetic association tests for disease risk and age at onset

Martin, ER., et al.
2021,  
Stem Cell Research

Derivation of stem cell line UMi028-A-2 containing a CRISPR/Cas9 induced Alzheimer's disease risk variant p.S1038C in the TTC3 gene

Laverde-Paz, MJ., et al.
2021,  
Acta Neuropathologica

Lack of evidence supporting a role for DPP6 sequence variants in Alzheimer's disease in the European American population

Kirola, L., et al.
2021,  
Neurology

Amyloid PET Imaging in Self-Identified Non-Hispanic Black Participants of the Anti-Amyloid in Asymptomatic Alzheimer's Disease (A4) Study

Deters, KD., et al.
2021,  
Genes

Set-Based Rare Variant Expression Quantitative Trait Loci in Blood and Brain from Alzheimer Disease Study Participants

Patel, D., et al.
2021,  
Nature Communications

Integration of Alzheimer's disease genetics and myeloid genomics identifies disease risk regulatory elements and genes

Novikova, G., et al.
2021,  
Alzheimer's Research & Therapy

Genome-wide epistasis analysis for Alzheimer's disease and implications for genetic risk prediction

Wang, H., et al.
2021,  
American Journal of Human Genetics

Genetic control of the human brain proteome

Robins, C., et al.
2021,  
Molecular Psychiatry

Brain expression of the vascular endothelial growth factor gene family in cognitive aging and alzheimer's disease

Mahoney, ER., et al.
2021,  
Neurobiology of Aging

Greater effect of polygenic risk score for Alzheimer's disease among younger cases who are apolipoprotein E-ε4 carriers

Fulton-Howard, B., et al.
2021,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

APOE alleles' association with cognitive function differs across Hispanic/Latino groups and genetic ancestry in the study of Latinos-investigation of neurocognitive aging (HCHS/SOL)

Granot-Hershkovitz, E., et al.
2021,  
Nature Genetics

Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture

Chia, R., et al.
2021,  
Translational Psychiatry

Long runs of homozygosity are associated with Alzheimer's disease

Moreno-Grau, S., et al.
2021,  
Neuron

Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis

Dewan, R., et al.
2021,  
Acta Neuropathologica

In vitro amplification of pathogenic tau conserves disease-specific bioactive characteristics

Xu, H., et al.
2021,  
Nature Genetics

Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer's disease pathogenesis

Wingo, AP., et al.
2021,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Non-coding variants in MYH11, FZD3, and SORCS3 are associated with dementia in women

Blue, EE., et al.
2021,  
Neuron

Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer's Disease

Wang, M., et al.
2021,  
Current Neurology and Neuroscience Reports

Early-Onset Alzheimer's Disease: What Is Missing in Research?

Ayodele, T., et al.
2021,  
Translational Psychiatry

A cortical immune network map identifies distinct microglial transcriptional programs associated with β-amyloid and Tau pathologies

Patrick, E., et al.
2021,  
Genome Biology

The variant call format provides efficient and robust storage of GWAS summary statistics

Lyon, MS., et al.
2021,  
JAMA neurology

Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis

Kunkle, BW., et al.
2021,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Education differentially contributes to cognitive reserve across racial/ethnic groups

Avila, JF., et al.
2021,  
Molecular Psychiatry

Genome-wide association study of brain amyloid deposition as measured by Pittsburgh Compound-B (PiB)-PET imaging

Yan, Q., et al.
2021,  
Journal of the American Geriatrics Society

A Systematic Review of Delirium Biomarkers and Their Alignment with the NIA-AA Research Framework

Wang, S., et al.
2021,  
Science Advances

Molecular subtyping of Alzheimer's disease using RNA sequencing data reveals novel mechanisms and targets

Neff, RA., et al.
2021,  
Annals of Neurology

Causal Associations Between Modifiable Risk Factors and the Alzheimer's Phenome

Andrews, SJ., et al.
2021,  
PLoS genetics

Identifying drug targets for neurological and psychiatric disease via genetics and the brain transcriptome

Baird, DA., et al.
2021,  
Frontiers in Neuroscience

Predicting Brain Amyloid Using Multivariate Morphometry Statistics, Sparse Coding, and Correntropy: Validation in 1,101 Individuals From the ADNI and OASIS Databases

Wu, J., et al.
2021,  
Methods in Molecular Biology (Clifton, N.J.)

Using INFERNO to Infer the Molecular Mechanisms Underlying Noncoding Genetic Associations

Amlie-Wolf, A., et al.
2021,  
Journal of Alzheimer's disease: JAD

Lower Levels of Education Are Associated with Cognitive Impairment in the Old Order Amish

Ramos, J., et al.
2021,  
Alzheimer's & Dementia (Amsterdam, Netherlands)

Large-scale sequencing studies expand the known genetic architecture of Alzheimer's disease

Xue, D., et al.

2020

2020,  
BMC bioinformatics

Deep learning detection of informative features in tau PET for Alzheimer's disease classification

Jo, T., et al.
2020,  
Science Translational Medicine

Chi3l1/YKL-40 is controlled by the astrocyte circadian clock and regulates neuroinflammation and Alzheimer's disease pathogenesis

Lananna, BV., et al.
2020,  
BMC medical informatics and decision making

Cognitive biomarker prioritization in Alzheimer's Disease using brain morphometric data

Peng, B., et al.
2020,  
European journal of human genetics: EJHG

A quantitative trait rare variant nonparametric linkage method with application to age-at-onset of Alzheimer's disease

Zhao, L., et al.
2020,  
NeuroImage

A comparison of Freesurfer and multi-atlas MUSE for brain anatomy segmentation: Findings about size and age bias, and inter-scanner stability in multi-site aging studies

Srinivasan, D., et al.
2020,  
Trends in Neurosciences

Microglial Phagocytosis: A Disease-Associated Process Emerging from Alzheimer's Disease Genetics

Podleśny-Drabiniok, A., et al.
2020,  
Acta Neuropathologica Communications

Functional genomic analyses uncover APOE-mediated regulation of brain and cerebrospinal fluid beta-amyloid levels in Parkinson disease

Ibanez, L., et al.
2020,  
IEEE transactions on medical imaging

Associating Multi-Modal Brain Imaging Phenotypes and Genetic Risk Factors via a Dirty Multi-Task Learning Method

Du, L., et al.
2020,  
Molecular Psychiatry

Genetic data and cognitively defined late-onset Alzheimer's disease subgroups

Mukherjee, S., et al.
2020,  
The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences

Parental History of Dementia Is Associated with Increased Small Vessel Cerebrovascular Disease

Stamm, BC., et al.
2020,  
NeuroImage

Longitudinal ComBat: A method for harmonizing longitudinal multi-scanner imaging data

Beer, JC., et al.
2020,  
JAMA neurology

Association Between Common Variants in RBFOX1, an RNA-Binding Protein, and Brain Amyloidosis in Early and Preclinical Alzheimer Disease

Raghavan, NS., et al.
2020,  
JAMA network open

Association of Uncommon, Noncoding Variants in the APOE Region With Risk of Alzheimer Disease in Adults of European Ancestry

Blue, EE., et al.
2020,  
Neurobiology of Aging

LRP10 variants in progressive supranuclear palsy

Vergouw, LJM., et al.
2020,  
Acta Neuropathologica

TREM2 activation on microglia promotes myelin debris clearance and remyelination in a model of multiple sclerosis

Cignarella, F., et al.
2020,  
Nature

Negative feedback control of neuronal activity by microglia

Badimon, A., et al.
2020,  
Nature Communications

Risk prediction of late-onset Alzheimer's disease implies an oligogenic architecture

Zhang, Q., et al.
2020,  
Nature Communications

Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults

Hofer, E., et al.
2020,  
Neurology

Cardiovascular health, genetic risk, and risk of dementia in the Framingham Heart Study

Peloso, GM., et al.
2020,  
EMBO molecular medicine

Higher CSF sTREM2 and microglia activation are associated with slower rates of beta-amyloid accumulation

Ewers, M., et al.
2020,  
Alzheimer's Research & Therapy

Analysis of brain region-specific co-expression networks reveals clustering of established and novel genes associated with Alzheimer disease

Lancour, D., et al.
2020,  
Journal of Neuropathology and Experimental Neurology

Insoluble Tau From Human FTDP-17 Cases Exhibit Unique Transmission Properties In Vivo

Weitzman, SA., et al.
2020,  
Cell Reports

Cross-Species Analyses Identify Dlgap2 as a Regulator of Age-Related Cognitive Decline and Alzheimer's Dementia

Ouellette, AR., et al.
2020,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Genome-wide transcriptome analysis identifies novel dysregulated genes implicated in Alzheimer's pathology

Nho, K., et al.
2020,  
Neurobiology of Disease

Genetic architecture of Alzheimer's disease

Neuner, SM., et al.
2020,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Circulating ethanolamine plasmalogen indices in Alzheimer's disease: Relation to diagnosis, cognition, and CSF tau

Kling, MA., et al.
2020,  
Genome Biology

PSCAN: Spatial scan tests guided by protein structures improve complex disease gene discovery and signal variant detection

Tang, Z., et al.
2020,  
Journal of the American Geriatrics Society

Measurement and Structure of Cognition in the Longitudinal Aging Study in India-Diagnostic Assessment of Dementia

Gross, AL., et al.
2020,  
Journal of the American Geriatrics Society

Introduction to LASI-DAD: The Longitudinal Aging Study in India-Diagnostic Assessment of Dementia

Lee, J.
2020,  
Journal of the American Geriatrics Society

Design and Methodology of the Longitudinal Aging Study in India-Diagnostic Assessment of Dementia (LASI-DAD)

Lee, J., et al.
2020,  
Journal of the American Geriatrics Society

Association Between Episodic Memory and Genetic Risk Factors for Alzheimer's Disease in South Asians from the Longitudinal Aging Study in India-Diagnostic Assessment of Dementia (LASI-DAD)

Smith, JA., et al.
2020,  
Neurology. Genetics

Synonymous variants associated with Alzheimer disease in multiplex families

Tang, M., et al.
2020,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Genome-wide association study of rate of cognitive decline in Alzheimer's disease patients identifies novel genes and pathways

Sherva, R., et al.
2020,  
Neurobiology of Disease

Genetic architecture of common non-Alzheimer's disease dementias

Guerreiro, R., et al.
2020,  
PLoS genetics

On the cross-population generalizability of gene expression prediction models

Keys, KL., et al.
2020,  
Brain: A Journal of Neurology

Genetic variants and functional pathways associated with resilience to Alzheimer's disease

Dumitrescu, L., et al.
2020,  
Molecular Psychiatry

Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation

Bis, JC., et al.
2020,  
Journal of the American Geriatrics Society

Hypertension and Cognitive Health Among Older Adults in India

Farron, MR., et al.
2020,  
Journal of the American Geriatrics Society

New Insights and Knowledge on Cognition and Dementia from Population-Based Cohort of Older Adults in India

Kenny, RA.
2020,  
Journal of the American Geriatrics Society

Online Clinical Consensus Diagnosis of Dementia: Development and Validation

Lee, J., et al.
2020,  
Journal of the American Geriatrics Society

Sex Differences in Cognitive Health Among Older Adults in India

Angrisani, M., et al.
2020,  
Brain: A Journal of Neurology

Sex-dependent autosomal effects on clinical progression of Alzheimer's disease

Fan, CC., et al.
2020,  
JAMA neurology

Association of Klotho-VS Heterozygosity With Risk of Alzheimer Disease in Individuals Who Carry APOE4

Belloy, ME., et al.
2020,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

MAPT haplotype-stratified GWAS reveals differential association for AD risk variants

Strickland, SL., et al.
2020,  
Stroke

Common Genetic Variation Indicates Separate Causes for Periventricular and Deep White Matter Hyperintensities

Armstrong, NJ., et al.
2020,  
Journal of the American Geriatrics Society

Interplay between Socioeconomic Markers and Polygenic Predisposition on Timing of Dementia Diagnosis

Ajnakina, O., et al.
2020,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Scientific Advising and Reviewing: On strengthening the bond between the Alzheimer's Association and the scientific community

Knopman, D., et al.
2020,  
Bioinformatics (Oxford, England)

SparkINFERNO: a scalable high-throughput pipeline for inferring molecular mechanisms of non-coding genetic variants

Kuksa, PP., et al.
2020,  
An International Journal on Information Fusion

Autosomal Dominantly Inherited Alzheimer Disease: Analysis of genetic subgroups by Machine Learning

Castillo-Barnes, D., et al.
2020,  
Neurobiology of Disease

Systematic validation of variants of unknown significance in APP, PSEN1 and PSEN2

Hsu, S., et al.
2020,  
NAR genomics and bioinformatics

HIPPIE2: a method for fine-scale identification of physically interacting chromatin regions

Kuksa, PP., et al.
2020,  
Alzheimer Disease and Associated Disorders

The Utility of the National Alzheimer's Coordinating Center's Database for the Rapid Assessment of Evolving Neuropathologic Conditions

Mock, C., et al.
2020,  
The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences

Time for Well-Powered Controlled Prospective Studies to Test a Causal Role for Herpes Viruses in Alzheimer's Disease Using Antiherpetic Drugs

Goldschmidt-Clermont, PJ., et al.
2020,  
Neurobiology of Aging

Failure to detect synergy between variants in transferrin and hemochromatosis and Alzheimer's disease in large cohort

Vance, E., et al.
2020,  
Neurology

Long-term exposure to air pollution and trajectories of cognitive decline among older adults

Kulick, ER., et al.
2020,  
JAMA psychiatry

Association of Copy Number Variation of the 15q11.2 BP1-BP2 Region With Cortical and Subcortical Morphology and Cognition

Writing Committee for the ENIGMA-CNV Working Group, ., et al.
2020,  
The Lancet. Neurology

Interpretation of risk loci from genome-wide association studies of Alzheimer's disease

Andrews, SJ., et al.
2020,  
Neurology. Genetics

Use of local genetic ancestry to assess TOMM40-523' and risk for Alzheimer disease

Bussies, PL., et al.
2020,  
Science (New York, N.Y.)

The genetic architecture of the human cerebral cortex

Grasby, KL., et al.
2020,  
Molecular Psychiatry

A rare loss-of-function variant of ADAM17 is associated with late-onset familial Alzheimer disease

Hartl, D., et al.
2020,  
Scientific Reports

Associations between brain inflammatory profiles and human neuropathology are altered based on apolipoprotein E ε4 genotype

Friedberg, JS., et al.
2020,  
The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences

Epigenetic Age Acceleration and Cognitive Function in African American Adults in Midlife: The Atherosclerosis Risk in Communities Study

Bressler, J., et al.
2020,  
Science Translational Medicine

APOE genotype regulates pathology and disease progression in synucleinopathy

Davis, AA., et al.
2020,  
Nature Communications

Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study

Reiman, EM., et al.
2020,  
Annals of Clinical and Translational Neurology

Circulating ceramide ratios and risk of vascular brain aging and dementia

McGrath, ER., et al.
2020,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Intact global cognitive and olfactory ability predicts lack of transition to dementia

Devanand, DP., et al.
2020,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Association between alcohol consumption and Alzheimer's disease: A Mendelian randomization study

Andrews, SJ., et al.
2020,  
PLoS genetics

Tensor decomposition of stimulated monocyte and macrophage gene expression profiles identifies neurodegenerative disease-specific trans-eQTLs

Ramdhani, S., et al.
2020,  
Current Opinion in Immunology

Innate sensing of mechanical properties of brain tissue by microglia

Ayata, P.
2020,  
Neurology

Association of CD14 with incident dementia and markers of brain aging and injury

Pase, MP., et al.
2020,  
Nature Communications

Transmission of tauopathy strains is independent of their isoform composition

He, Z., et al.
2020,  
The Lancet. Neurology

Antihypertensive medications and risk for incident dementia and Alzheimer's disease: a meta-analysis of individual participant data from prospective cohort studies

Ding, J., et al.
2020,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Two-stage Bayesian GWAS of 9576 individuals identifies SNP regions that are targeted by miRNAs inversely expressed in Alzheimer's and cancer

Pathak, GA., et al.
2020,  
Acta Neuropathologica

The TMEM106B FTLD-protective variant, rs1990621, is also associated with increased neuronal proportion

Li, Z., et al.
2020,  
Neuropsychology

Linking depressive symptoms and cognitive functioning: The mediating role of leisure activity

Sharifian, N., et al.
2020,  
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing

Packaging Biocomputing Software to Maximize Distribution and Reuse

Bush, WS., et al.
2020,  
Alzheimer's & Dementia (New York, N. Y.)

Development and validation of language and visuospatial composite scores in ADNI

Choi, S., et al.
2020,  
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing

Hadoop and PySpark for reproducibility and scalability of genomic sequencing studies

Wheeler, NR., et al.
2020,  
Journal of Alzheimer's disease: JAD

Circulating Vitamin D Levels and Alzheimer's Disease: A Mendelian Randomization Study in the IGAP and UK Biobank

Wang, L., et al.
2020,  
Alzheimer's & Dementia (New York, N. Y.)

Differences in plasma metabolites related to Alzheimer's disease, APOE ε4 status, and ethnicity

Vardarajan, B., et al.
2020,  
Journal of Alzheimer's disease: JAD

Immune and Inflammatory Pathways Implicated by Whole Blood Transcriptomic Analysis in a Diverse Ancestry Alzheimer's Disease Cohort

Griswold, AJ., et al.
2020,  
Journal of Alzheimer's disease: JAD

Examination of the Effect of Rare Variants in TREM2, ABI3, and PLCG2 in LOAD Through Multiple Phenotypes

Olive, C., et al.
2020,  
Journal of Alzheimer's disease: JAD

A Coordinated Approach by Public Domain Bioinformatics Resources to Aid the Fight Against Alzheimer's Disease Through Expert Curation of Key Protein Targets

Breuza, L., et al.
2020,  
Computational and Structural Biotechnology Journal

HiPR: High-throughput probabilistic RNA structure inference

Kuksa, PP., et al.

2019

2019,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

A research framework for cognitive aging and Alzheimer's disease among diverse US Latinos: Design and implementation of the Hispanic Community Health Study/Study of Latinos-Investigation of Neurocognitive Aging (SOL-INCA)

González, HM., et al.
2019,  
PLoS genetics

Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations

Kowalski, MH., et al.
2019,  
Alzheimer's & Dementia (Amsterdam, Netherlands)

Harmonizing brain magnetic resonance imaging methods for vascular contributions to neurodegeneration

Smith, EE., et al.
2019,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Local ancestry at APOE modifies Alzheimer's disease risk in Caribbean Hispanics

Blue, EE., et al.
2019,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Secular trends in cognitive trajectories of diverse older adults

Vonk, JMJ., et al.
2019,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Current and past leisure time physical activity in relation to risk of Alzheimer's disease in older adults

Ogino, E., et al.
2019,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Sex/gender differences in cognitive trajectories vary as a function of race/ethnicity

Avila, JF., et al.
2019,  
Brain: A Journal of Neurology

Genetic and epigenetic study of an Alzheimer's disease family with monozygotic triplets

Zhang, M., et al.
2019,  
Nature Neuroscience

An atlas of cortical circular RNA expression in Alzheimer disease brains demonstrates clinical and pathological associations

Dube, U., et al.
2019,  
Nature Genetics

Genetic architecture of subcortical brain structures in 38,851 individuals

Satizabal, CL., et al.
2019,  
Neuroscience Letters

Promoter DNA hypermethylation - Implications for Alzheimer's disease

Liu, Y., et al.
2019,  
American Journal of Human Genetics

A Rare Variant Nonparametric Linkage Method for Nuclear and Extended Pedigrees with Application to Late-Onset Alzheimer Disease via WGS Data

Zhao, L., et al.
2019,  
Circulation Research

Circulating Monocyte Chemoattractant Protein-1 and Risk of Stroke: Meta-Analysis of Population-Based Studies Involving 17 180 Individuals

Georgakis, MK., et al.
2019,  
Nature Communications

Genome-wide identification of DNA methylation QTLs in whole blood highlights pathways for cardiovascular disease

Huan, T., et al.
2019,  
Human Molecular Genetics

RNA editing alterations in a multi-ethnic Alzheimer disease cohort converge on immune and endocytic molecular pathways

Gardner, OK., et al.
2019,  
Brain: A Journal of Neurology

Sex differences in the genetic predictors of Alzheimer's pathology

Dumitrescu, L., et al.
2019,  
JAMA neurology

Analysis of Whole-Exome Sequencing Data for Alzheimer Disease Stratified by APOE Genotype

Ma, Y., et al.
2019,  
Liver International: Official Journal of the International Association for the Study of the Liver

Non-alcoholic fatty liver disease, liver fibrosis score and cognitive function in middle-aged adults: The Framingham Study

Weinstein, G., et al.
2019,  
Nature Genetics

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Kunkle, BW., et al.
2019,  
Science Translational Medicine

Increased soluble TREM2 in cerebrospinal fluid is associated with reduced cognitive and clinical decline in Alzheimer's disease

Ewers, M., et al.
2019,  
Journal of Clinical Medicine

APOE Promoter Polymorphism-219T/G is an Effect Modifier of the Influence of APOE ε4 on Alzheimer's Disease Risk in a Multiracial Sample

Choi, KY., et al.
2019,  
Science Translational Medicine

The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer's disease risk

Deming, Y., et al.
2019,  
Alzheimer's Research & Therapy

A single-nuclei RNA sequencing study of Mendelian and sporadic AD in the human brain

Del-Aguila, JL., et al.
2019,  
American Journal of Human Genetics

TIGAR: An Improved Bayesian Tool for Transcriptomic Data Imputation Enhances Gene Mapping of Complex Traits

Nagpal, S., et al.
2019,  
The American Journal of Clinical Nutrition

Association of dietary folate and vitamin B-12 intake with genome-wide DNA methylation in blood: a large-scale epigenome-wide association analysis in 5841 individuals

Mandaviya, PR., et al.
2019,  
JAMA neurology

Association of Variants in PINX1 and TREM2 With Late-Onset Alzheimer Disease

Tosto, G., et al.
2019,  
Aging Cell

CpG-related SNPs in the MS4A region have a dose-dependent effect on risk of late-onset Alzheimer disease

Ma, Y., et al.
2019,  
Cell Reports

Integrating Gene and Protein Expression Reveals Perturbed Functional Networks in Alzheimer's Disease

Canchi, S., et al.
2019,  
Genomics

Quality control and integration of genotypes from two calling pipelines for whole genome sequence data in the Alzheimer's disease sequencing project

Naj, AC., et al.
2019,  
Bioinformatics (Oxford, England)

VCPA: genomic variant calling pipeline and data management tool for Alzheimer's Disease Sequencing Project

Leung, YY., et al.
2019,  
Nature

Genetic analyses of diverse populations improves discovery for complex traits

Wojcik, GL., et al.
2019,  
Genome Biology

Systematic analysis of dark and camouflaged genes reveals disease-relevant genes hiding in plain sight

Ebbert, MTW., et al.
2019,  
Nature Communications

Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function

Davies, G., et al.
2019,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Brain arterial dilatation and the risk of Alzheimer's disease

Gutierrez, J., et al.
2019,  
Neurology

A prospective study of serum metabolites and risk of ischemic stroke

Sun, D., et al.
2019,  
JAMA network open

Association of Accelerometer-Measured Light-Intensity Physical Activity With Brain Volume: The Framingham Heart Study

Spartano, NL., et al.
2019,  
Brain: A Journal of Neurology

Association of variants in HTRA1 and NOTCH3 with MRI-defined extremes of cerebral small vessel disease in older subjects

Mishra, A., et al.
2019,  
Annals of Clinical and Translational Neurology

Alternative splicing in a presenilin 2 variant associated with Alzheimer disease

Braggin, JE., et al.
2019,  
Nature Genetics

Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids

Bentley, AR., et al.
2019,  
JAMA network open

Association of Rare Coding Mutations With Alzheimer Disease and Other Dementias Among Adults of European Ancestry

Patel, D., et al.
2019,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

A rare missense variant of CASP7 is associated with familial late-onset Alzheimer's disease

Zhang, X., et al.
2019,  
Nature Genetics

Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Kunkle, BW., et al.
2019,  
Blood

A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology

de Vries, PS., et al.
2019,  
Neurology

Serum magnesium and calcium levels in relation to ischemic stroke: Mendelian randomization study

Larsson, SC., et al.
2019,  
Neurology

The emerging genetic landscape of cerebral white matter hyperintensities

Fornage, M.
2019,  
Acta Neuropathologica

Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer's disease

Broce, IJ., et al.
2019,  
Briefings in Bioinformatics

Association score testing for rare variants and binary traits in family data with shared controls

Saad, M.
2019,  
Journal of Diabetes Research

Self-Reported Physical Activity and Relations to Growth and Neurotrophic Factors in Diabetes Mellitus: The Framingham Offspring Study

Spartano, NL., et al.
2019,  
Alzheimer's & Dementia (New York, N. Y.)

Accelerometer-determined physical activity and cognitive function in middle-aged and older adults from two generations of the Framingham Heart Study

Spartano, NL., et al.
2019,  
Communications Biology

A genome-wide association study identifies genetic loci associated with specific lobar brain volumes

van der Lee, SJ., et al.
2019,  
PloS One

Association of metformin, sulfonylurea and insulin use with brain structure and function and risk of dementia and Alzheimer's disease: Pooled analysis from 5 cohorts

Weinstein, G., et al.
2019,  
Journal of Alzheimer's disease: JAD

Education Moderates the Relation Between APOE ɛ4 and Memory in Nondemented Non-Hispanic Black Older Adults

Vonk, JMJ., et al.
2019,  
PloS One

Gene-based analysis in HRC imputed genome wide association data identifies three novel genes for Alzheimer's disease

Baker, E., et al.
2019,  
Frontiers in Genetics

Rare Variants Imputation in Admixed Populations: Comparison Across Reference Panels and Bioinformatics Tools

Sariya, S., et al.
2019,  
Frontiers in Genetics

The Puerto Rico Alzheimer Disease Initiative (PRADI): A Multisource Ascertainment Approach

Feliciano-Astacio, BE., et al.
2019,  
Journal of Alzheimer's disease: JAD

Inferring the Molecular Mechanisms of Noncoding Alzheimer's Disease-Associated Genetic Variants

Amlie-Wolf, A., et al.
2019,  
PloS One

The impact of APOE genotype on survival: Results of 38,537 participants from six population-based cohorts (E2-CHARGE)

Wolters, FJ., et al.
2019,  
Genome Research

Comparison and assessment of family- and population-based genotype imputation methods in large pedigrees

Ullah, E., et al.

2018

2018,  
Translational Psychiatry

Integrative system biology analyses of CRISPR-edited iPSC-derived neurons and human brains reveal deficiencies of presynaptic signaling in FTLD and PSP

Jiang, S., et al.
2018,  
PLoS genetics

Ancestral origin of ApoE ε4 Alzheimer disease risk in Puerto Rican and African American populations

Rajabli, F., et al.
2018,  
Neurobiology of Aging

Male-specific epistasis between WWC1 and TLN2 genes is associated with Alzheimer's disease

Gusareva, ES., et al.
2018,  
Acta Neuropathologica

Sex-specific genetic predictors of Alzheimer's disease biomarkers

Deming, Y., et al.
2018,  
Neurology. Genetics

Rare genetic variation implicated in non-Hispanic white families with Alzheimer disease

Beecham, GW., et al.
2018,  
Nucleic Acids Research

INFERNO: inferring the molecular mechanisms of noncoding genetic variants

Amlie-Wolf, A., et al.
2018,  
Stroke

Circulating Vascular Growth Factors and Magnetic Resonance Imaging Markers of Small Vessel Disease and Atrophy in Middle-Aged Adults

Raman, MR., et al.
2018,  
Genetic Epidemiology

Analysis of pedigree data in populations with multiple ancestries: Strategies for dealing with admixture in Caribbean Hispanic families from the ADSP

Nafikov, RA., et al.
2018,  
Bioinformatics (Oxford, England)

Functional annotation of genomic variants in studies of late-onset Alzheimer's disease

Butkiewicz, M., et al.
2018,  
Stroke

Exome Chip Analysis Identifies Low-Frequency and Rare Variants in MRPL38 for White Matter Hyperintensities on Brain Magnetic Resonance Imaging

Jian, X., et al.
2018,  
Bioinformatics (Oxford, England)

Integrative DNA copy number detection and genotyping from sequencing and array-based platforms

Zhou, Z., et al.
2018,  
Genes, Brain, and Behavior

Variants regulating ZBTB4 are associated with age-at-onset of Alzheimer's disease

Blue, EE., et al.
2018,  
Annals of Clinical and Translational Neurology

Whole-exome sequencing in 20,197 persons for rare variants in Alzheimer's disease

Raghavan, NS., et al.
2018,  
Preventive Medicine

Vascular risk factor burden and new-onset depression in the community

Adams, S., et al.
2018,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Association of branched-chain amino acids and other circulating metabolites with risk of incident dementia and Alzheimer's disease: A prospective study in eight cohorts

Tynkkynen, J., et al.
2018,  
Translational Psychiatry

GWAS on family history of Alzheimer's disease

Marioni, RE., et al.
2018,  
Bioinformatics (Oxford, England)

GIGI-Quick: a fast approach to impute missing genotypes in genome-wide association family data

Kunji, K., et al.
2018,  
Annals of Clinical and Translational Neurology

Whole genome sequencing of Caribbean Hispanic families with late-onset Alzheimer's disease

Vardarajan, BN., et al.
2018,  
PloS One

The APOE ε4 allele is associated with a reduction in FEV1/FVC in women: A cross-sectional analysis of the Long Life Family Study

Kulminski, AM., et al.
2018,  
Journal of Alzheimer's disease: JAD

Genetic Interaction with Plasma Lipids on Alzheimer's Disease in the Framingham Heart Study

Peloso, GM., et al.
2018,  
Dementia and Geriatric Cognitive Disorders

Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer's Disease Sequencing Project

Blue, EE., et al.

2017

2017,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Alzheimer's Disease Sequencing Project discovery and replication criteria for cases and controls: Data from a community-based prospective cohort study with autopsy follow-up

Crane, PK., et al.
2017,  
PLoS genetics

Analysis of neurodegenerative Mendelian genes in clinically diagnosed Alzheimer Disease

Fernández, MV., et al.
2017,  
Molecular Neurodegeneration

Whole blood gene expression and white matter Hyperintensities

Lin, H., et al.
2017,  
Bioinformatics (Oxford, England)

Introducing COCOS: codon consequence scanner for annotating reading frame changes induced by stop-lost and frame shift variants

Butkiewicz, M., et al.
2017,  
Journal of Alzheimer's disease: JAD

Methionine Sulfoxide Reductase-B3 (MsrB3) Protein Associates with Synaptic Vesicles and its Expression Changes in the Hippocampi of Alzheimer's Disease Patients

Adams, SL., et al.

2016

2016,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Genome-wide linkage analyses of non-Hispanic white families identify novel loci for familial late-onset Alzheimer's disease

Kunkle, BW., et al.

2015

2015,  
Alzheimer's & Dementia: The Journal of the Alzheimer's Association

Linkage analyses in Caribbean Hispanic families identify novel loci associated with familial late-onset Alzheimer's disease

Barral, S., et al.